prot_M-pyrifera_M_contig102364.506.1 (polypeptide) Macrocystis pyrifera P11B4 male

You are viewing a polypeptide, more information available on the corresponding mRNA page

Overview
NamemRNA_M-pyrifera_M_contig102364.506.1
Unique Nameprot_M-pyrifera_M_contig102364.506.1
Typepolypeptide
OrganismMacrocystis pyrifera P11B4 male (Macrocystis pyrifera P11B4 male (Giant kelp))
Sequence length219
Homology
BLAST of mRNA_M-pyrifera_M_contig102364.506.1 vs. uniprot
Match: A0A1S9D2W6_9GAMM (Pyruvate kinase n=1 Tax=Chromatiales bacterium USCg_Taylor TaxID=1934255 RepID=A0A1S9D2W6_9GAMM)

HSP 1 Score: 291 bits (744), Expect = 6.680e-94
Identity = 152/216 (70.37%), Postives = 172/216 (79.63%), Query Frame = 0
Query:    3 KRLIKKARAMNRGIITATQMMESMIENHIPTRAEVFDVANAVIDGTDAVMLSAETSIGKYPEKVVEAMARICTETEKARGSVGADYRIGQEFADIDETIAMSTMYAANHLNVKAIVALTETGSTTKWMSRTRSSIPIFAFTRTAKTCRRVTLFRGVYPFLYDITHSDYLEANKEMIDVLKAHNAVKDGDIVIITKGDLKGHQGGTNNMKIVKVGEL 218
            KRLI +AR  NR +ITATQMMESMI N IPTRAEVFDVANAV+DGTDAVMLSAETS+GKYP K VEAM RIC ETE   G  GADYRI   F  IDE IAMST+YAANH+  KAI+ALTETG+T  WMSR  + IPIFAFTR   T RRVTL+RGVYP  +D+TH+D+L  N+EMID+L    AV + DIV+ITKGDL+G QGGTN MKIV+VGEL
Sbjct:  237 KRLILQARNANRLVITATQMMESMIANQIPTRAEVFDVANAVLDGTDAVMLSAETSVGKYPRKAVEAMDRICLETETQWGLRGADYRIDSLFDRIDEAIAMSTVYAANHIGAKAILALTETGATGIWMSRVLTGIPIFAFTRHPMTLRRVTLYRGVYPINFDVTHTDFLRVNREMIDILLERGAVHEEDIVVITKGDLRGKQGGTNGMKIVRVGEL 452          
BLAST of mRNA_M-pyrifera_M_contig102364.506.1 vs. uniprot
Match: A0A849MIF2_9PROT (Pyruvate kinase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A849MIF2_9PROT)

HSP 1 Score: 290 bits (743), Expect = 1.780e-93
Identity = 151/219 (68.95%), Postives = 175/219 (79.91%), Query Frame = 0
Query:    1 VQKRLIKKARAMNRGIITATQMMESMIENHIPTRAEVFDVANAVIDGTDAVMLSAETSIGKYPEKVVEAMARICTETEKARGSVGADYRIGQEFADIDETIAMSTMYAANHLNVKAIVALTETGSTTKWMSRTRSSIPIFAFTRTAKTCRRVTLFRGVYPFLYDITHSDYLEANKEMIDVLKAHNAVKDGDIVIITKGDLKGHQGGTNNMKIVKVGELV 219
            VQK LIK AR M+R +ITATQMMESMIE+ IPTRAEVFDVANAVIDGTDAVMLS ETSIG YP+KVVEAM+R+C E EK R    +D+RI Q F  I E +AMS+MYAANH+  KAI ALTETG T  WMSR  S +PIFAFTR   T RRV L+RGVYP  +DITH+D LEANK+MI+ L    AV+DGDIVIITKGDL+G +GGTNNMKI++VG+ +
Sbjct:  258 VQKSLIKMARDMDRAVITATQMMESMIEHKIPTRAEVFDVANAVIDGTDAVMLSGETSIGHYPDKVVEAMSRVCEEAEKQRSVRISDHRINQRFETISEAVAMSSMYAANHIGAKAICALTETGGTCLWMSRISSGLPIFAFTRNTSTRRRVGLYRGVYPMKFDITHTDPLEANKQMINQLIEFGAVEDGDIVIITKGDLRGKRGGTNNMKIIQVGQAL 476          
BLAST of mRNA_M-pyrifera_M_contig102364.506.1 vs. uniprot
Match: A0A1G0JQ64_9GAMM (Pyruvate kinase n=1 Tax=Gammaproteobacteria bacterium RIFCSPLOWO2_12_47_11 TaxID=1798301 RepID=A0A1G0JQ64_9GAMM)

HSP 1 Score: 290 bits (743), Expect = 1.780e-93
Identity = 148/219 (67.58%), Postives = 177/219 (80.82%), Query Frame = 0
Query:    1 VQKRLIKKARAMNRGIITATQMMESMIENHIPTRAEVFDVANAVIDGTDAVMLSAETSIGKYPEKVVEAMARICTETEKARGSVGADYRIGQEFADIDETIAMSTMYAANHLNVKAIVALTETGSTTKWMSRTRSSIPIFAFTRTAKTCRRVTLFRGVYPFLYDITHSDYLEANKEMIDVLKAHNAVKDGDIVIITKGDLKGHQGGTNNMKIVKVGELV 219
            VQKRLIK AR M+R +ITATQMMESMI++ +PTRAEVFDVANAV+DG DAVMLSAETS+G YP+K V AM+R+C E EK R +  +D+RI Q F  IDE IAM+TMY+ANH++ KAI ALTETGST  WMSR  S IPIFAFTR + T R+V+L+RGVYP  +DITH+D L ANKE+ID L A N V +GD V+ITKGDL G +GGTNNMKI+KVGE +
Sbjct:  258 VQKRLIKMARDMDRAVITATQMMESMIDHQMPTRAEVFDVANAVLDGADAVMLSAETSVGNYPDKAVAAMSRVCAEAEKQRVTQVSDHRINQRFEAIDEAIAMATMYSANHIDAKAIAALTETGSTCMWMSRISSGIPIFAFTRHSSTRRQVSLYRGVYPVKFDITHTDPLMANKEIIDELLARNVVSNGDYVVITKGDLLGRRGGTNNMKIIKVGESI 476          
BLAST of mRNA_M-pyrifera_M_contig102364.506.1 vs. uniprot
Match: A0A2E0PV68_9GAMM (Pyruvate kinase n=1 Tax=Legionellales bacterium TaxID=2026754 RepID=A0A2E0PV68_9GAMM)

HSP 1 Score: 288 bits (737), Expect = 1.420e-92
Identity = 150/219 (68.49%), Postives = 172/219 (78.54%), Query Frame = 0
Query:    1 VQKRLIKKARAMNRGIITATQMMESMIENHIPTRAEVFDVANAVIDGTDAVMLSAETSIGKYPEKVVEAMARICTETEKARGSVGADYRIGQEFADIDETIAMSTMYAANHLNVKAIVALTETGSTTKWMSRTRSSIPIFAFTRTAKTCRRVTLFRGVYPFLYDITHSDYLEANKEMIDVLKAHNAVKDGDIVIITKGDLKGHQGGTNNMKIVKVGELV 219
            VQK LIK AR M+R +ITATQMMESM+EN IPTRAEVFDVANAVIDGTDAVMLS ETS+G YP+KVVEAM+ IC E EK R    +D+RI Q F  I E IAMS+MY+ANH+N KAI +LTETGST  WMSR  S IPIFAF R   T RRV L+RGVYP  +DITH+D LEANK+MID L     VK+GD VIITKGDL G +GGTNNMKI++VG+ +
Sbjct:  258 VQKSLIKMARKMDRAVITATQMMESMVENKIPTRAEVFDVANAVIDGTDAVMLSGETSVGCYPDKVVEAMSSICEEAEKQRSVRISDHRINQSFETISEAIAMSSMYSANHINAKAICSLTETGSTCLWMSRISSVIPIFAFARHTSTRRRVALYRGVYPMKFDITHTDPLEANKQMIDQLITEGVVKEGDFVIITKGDLHGRRGGTNNMKIIQVGQAL 476          
BLAST of mRNA_M-pyrifera_M_contig102364.506.1 vs. uniprot
Match: A0A1G0K6Z2_9GAMM (Pyruvate kinase n=1 Tax=Gammaproteobacteria bacterium RIFCSPLOWO2_02_FULL_61_13 TaxID=1798300 RepID=A0A1G0K6Z2_9GAMM)

HSP 1 Score: 286 bits (733), Expect = 5.540e-92
Identity = 146/217 (67.28%), Postives = 171/217 (78.80%), Query Frame = 0
Query:    1 VQKRLIKKARAMNRGIITATQMMESMIENHIPTRAEVFDVANAVIDGTDAVMLSAETSIGKYPEKVVEAMARICTETEKARGSVGADYRIGQEFADIDETIAMSTMYAANHLNVKAIVALTETGSTTKWMSRTRSSIPIFAFTRTAKTCRRVTLFRGVYPFLYDITHSDYLEANKEMIDVLKAHNAVKDGDIVIITKGDLKGHQGGTNNMKIVKVGE 217
            VQK LIK AR M+R +ITATQMMESMIEN +P RAEVFDVANAV DGTDAVMLS ETS+GKYP+KVV+AMARIC ETEK R +  +D+RI Q F  IDE +AM+ MYAANH+  KAI ALTETGSTT WMSR  S IP+FAFTR  +  RRV L+RGVYP  +DITH+D L+AN E+++ L     V D D V+ITKGDL GH+GGTNNMKIV+ G+
Sbjct:  257 VQKHLIKLARDMDRAVITATQMMESMIENQVPLRAEVFDVANAVFDGTDAVMLSGETSVGKYPDKVVQAMARICAETEKQRVTRVSDHRINQRFERIDEAVAMAAMYAANHIGAKAIAALTETGSTTLWMSRISSGIPVFAFTRHIECRRRVRLYRGVYPIHFDITHTDPLQANAEIVEELMRRRMVFDNDFVVITKGDLSGHRGGTNNMKIVRAGQ 473          
BLAST of mRNA_M-pyrifera_M_contig102364.506.1 vs. uniprot
Match: A0A1G0FXK3_9GAMM (Pyruvate kinase n=1 Tax=Gammaproteobacteria bacterium RBG_16_51_14 TaxID=1798265 RepID=A0A1G0FXK3_9GAMM)

HSP 1 Score: 286 bits (733), Expect = 5.700e-92
Identity = 149/217 (68.66%), Postives = 172/217 (79.26%), Query Frame = 0
Query:    1 VQKRLIKKARAMNRGIITATQMMESMIENHIPTRAEVFDVANAVIDGTDAVMLSAETSIGKYPEKVVEAMARICTETEKARGSVGADYRIGQEFADIDETIAMSTMYAANHLNVKAIVALTETGSTTKWMSRTRSSIPIFAFTRTAKTCRRVTLFRGVYPFLYDITHSDYLEANKEMIDVLKAHNAVKDGDIVIITKGDLKGHQGGTNNMKIVKVGE 217
            VQKRLI+ AR+ +R +ITATQMM+SMIE+ +PTRAEVFDVANAV+DGTDAVMLS ETSIGKYPE  V AM+RIC ETEK R    +D+RI Q F +IDE IAMSTMYAANH+  KAI ALTETGST  WMSR  S IPIFAFTR   T RRV+L+RGVYP  +DITH+D L  N+E+ID L A   V  GD VIITKGDL+G +GGTNNMKI++ GE
Sbjct:  258 VQKRLIQLARSRDRAVITATQMMQSMIEHQMPTRAEVFDVANAVLDGTDAVMLSGETSIGKYPEMAVLAMSRICEETEKQRSIRVSDHRINQRFEEIDEAIAMSTMYAANHIGAKAIAALTETGSTCLWMSRISSGIPIFAFTRHETTRRRVSLYRGVYPIKFDITHTDPLAVNREIIDELMARKIVNKGDYVIITKGDLRGRKGGTNNMKIIRAGE 474          
BLAST of mRNA_M-pyrifera_M_contig102364.506.1 vs. uniprot
Match: A0A2N2ADD0_9GAMM (Pyruvate kinase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A2N2ADD0_9GAMM)

HSP 1 Score: 286 bits (732), Expect = 7.400e-92
Identity = 149/219 (68.04%), Postives = 174/219 (79.45%), Query Frame = 0
Query:    1 VQKRLIKKARAMNRGIITATQMMESMIENHIPTRAEVFDVANAVIDGTDAVMLSAETSIGKYPEKVVEAMARICTETEKARGSVGADYRIGQEFADIDETIAMSTMYAANHLNVKAIVALTETGSTTKWMSRTRSSIPIFAFTRTAKTCRRVTLFRGVYPFLYDITHSDYLEANKEMIDVLKAHNAVKDGDIVIITKGDLKGHQGGTNNMKIVKVGELV 219
            VQK LI+ AR MNR +ITATQMMESMIEN IPTRAEVFDVANAV+DGTDAVMLSAET+ GKYP+K ++AM R+C E EK R ++ +D+RI  +F  IDE IAMSTMY ANHLNVKAI ALTE+GST  WMSR  S IPI+A TR  +T R+VTL+RGVYP  +D+  +D+ E N+E ID L    AV+DGD+VIITKGDL G  GGTN MKIVKVGELV
Sbjct:  259 VQKHLIQLARKMNRVVITATQMMESMIENPIPTRAEVFDVANAVLDGTDAVMLSAETASGKYPDKAIQAMDRVCVEAEKQRIAIQSDHRIHTQFTYIDEAIAMSTMYTANHLNVKAIAALTESGSTPLWMSRISSGIPIYAMTRHVETRRKVTLYRGVYPVSFDVQTTDHAEVNREAIDELLRRGAVRDGDLVIITKGDLMGMHGGTNAMKIVKVGELV 477          
BLAST of mRNA_M-pyrifera_M_contig102364.506.1 vs. uniprot
Match: A0A1G5QJN9_9GAMM (Pyruvate kinase n=1 Tax=Thiohalomonas denitrificans TaxID=415747 RepID=A0A1G5QJN9_9GAMM)

HSP 1 Score: 282 bits (722), Expect = 2.370e-90
Identity = 146/219 (66.67%), Postives = 173/219 (79.00%), Query Frame = 0
Query:    1 VQKRLIKKARAMNRGIITATQMMESMIENHIPTRAEVFDVANAVIDGTDAVMLSAETSIGKYPEKVVEAMARICTETEKARGSVGADYRIGQEFADIDETIAMSTMYAANHLNVKAIVALTETGSTTKWMSRTRSSIPIFAFTRTAKTCRRVTLFRGVYPFLYDITHSDYLEANKEMIDVLKAHNAVKDGDIVIITKGDLKGHQGGTNNMKIVKVGELV 219
            VQKRLI +AR MNR +ITATQMMESMIEN IPTRAEVFDVAN+V+DGTDAVMLSAET+ GKYP+K + AM R+C E EK R +  + +RI  EF  IDE IAM++MY ANHLNVKAI +LTE+GST  WMSR  S IPI+A TR   T R+VTLFRGVYP  +D+T +D+++ N+E ID L    AV+DGD+VIITKGDL G  GGTN +KIVKVGELV
Sbjct:  259 VQKRLITRARDMNRVVITATQMMESMIENQIPTRAEVFDVANSVLDGTDAVMLSAETAAGKYPDKAIAAMDRVCREAEKQREATTSAHRIHSEFTHIDEAIAMASMYTANHLNVKAIASLTESGSTPLWMSRISSGIPIYAMTRHVDTRRKVTLFRGVYPVSFDVTTADHVQVNREAIDELLRRGAVRDGDLVIITKGDLMGVHGGTNAIKIVKVGELV 477          
BLAST of mRNA_M-pyrifera_M_contig102364.506.1 vs. uniprot
Match: A0A661BV09_9GAMM (Pyruvate kinase n=2 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A661BV09_9GAMM)

HSP 1 Score: 282 bits (722), Expect = 2.580e-90
Identity = 145/217 (66.82%), Postives = 172/217 (79.26%), Query Frame = 0
Query:    1 VQKRLIKKARAMNRGIITATQMMESMIENHIPTRAEVFDVANAVIDGTDAVMLSAETSIGKYPEKVVEAMARICTETEKARGSVGADYRIGQEFADIDETIAMSTMYAANHLNVKAIVALTETGSTTKWMSRTRSSIPIFAFTRTAKTCRRVTLFRGVYPFLYDITHSDYLEANKEMIDVLKAHNAVKDGDIVIITKGDLKGHQGGTNNMKIVKVGE 217
            VQKRL K AR M+R +I ATQMMESMIE+ IPTRAEVFDVANAVIDG DAVMLSAETS+G +P K V +M+ IC E EK +    +D+RI + F  I+E IAMSTMYAANH+  KAI ALTETG T  WMSR +S IPIFAFTR + T RRV+L+RGVYP  +DITH+D LEANKE++D L   N V+DGD VIITKGDL+G +GGTNNMK+++VGE
Sbjct:  258 VQKRLTKMARGMDRAVIIATQMMESMIEHQIPTRAEVFDVANAVIDGADAVMLSAETSVGHFPVKAVTSMSGICEEAEKQKSVTVSDHRINRRFESINEAIAMSTMYAANHIGAKAIAALTETGGTCLWMSRIKSGIPIFAFTRHSSTRRRVSLYRGVYPMKFDITHTDPLEANKEILDELLDKNIVEDGDYVIITKGDLRGARGGTNNMKLIRVGE 474          
BLAST of mRNA_M-pyrifera_M_contig102364.506.1 vs. uniprot
Match: UPI0018DCB5A9 (pyruvate kinase n=1 Tax=sulfur-oxidizing endosymbiont of Gigantopelta aegis TaxID=2794934 RepID=UPI0018DCB5A9)

HSP 1 Score: 282 bits (722), Expect = 2.800e-90
Identity = 148/219 (67.58%), Postives = 172/219 (78.54%), Query Frame = 0
Query:    1 VQKRLIKKARAMNRGIITATQMMESMIENHIPTRAEVFDVANAVIDGTDAVMLSAETSIGKYPEKVVEAMARICTETEKARGSVGADYRIGQEFADIDETIAMSTMYAANHLNVKAIVALTETGSTTKWMSRTRSSIPIFAFTRTAKTCRRVTLFRGVYPFLYDITHSDYLEANKEMIDVLKAHNAVKDGDIVIITKGDLKGHQGGTNNMKIVKVGELV 219
            +QKRLI   R MNR +ITATQMMESMIEN IPTRAEVFDVANAV+DGTDAVMLSAET+ GK+P K + AM RIC E EK R +  +D+RI  EF  IDE IAMSTMY ANHL VKAIVALTE+GSTT WMSR  S IPIFAFT    T R+VTL+RGV P  +DIT +D+ E N+E++D LK   +V+DGD+V+ITKGDL G  GGTN MKIVKVG+L+
Sbjct:  259 IQKRLISLGRTMNRVVITATQMMESMIENQIPTRAEVFDVANAVLDGTDAVMLSAETAAGKFPAKAIIAMDRICREAEKQRQASQSDHRIHTEFKYIDEAIAMSTMYTANHLKVKAIVALTESGSTTLWMSRIGSGIPIFAFTGHVDTRRKVTLYRGVVPVSFDITTTDHAELNREVVDELKRRGSVRDGDLVVITKGDLAGVMGGTNAMKIVKVGDLI 477          
The following BLAST results are available for this feature:
BLAST of mRNA_M-pyrifera_M_contig102364.506.1 vs. uniprot
Analysis Date: 2022-09-16 (Diamond blastp: OGS1.0 of Macrocystis pyrifera male vs UniRef90)
Total hits: 25
Match NameE-valueIdentityDescription
A0A1S9D2W6_9GAMM6.680e-9470.37Pyruvate kinase n=1 Tax=Chromatiales bacterium USC... [more]
A0A849MIF2_9PROT1.780e-9368.95Pyruvate kinase n=2 Tax=Proteobacteria TaxID=1224 ... [more]
A0A1G0JQ64_9GAMM1.780e-9367.58Pyruvate kinase n=1 Tax=Gammaproteobacteria bacter... [more]
A0A2E0PV68_9GAMM1.420e-9268.49Pyruvate kinase n=1 Tax=Legionellales bacterium Ta... [more]
A0A1G0K6Z2_9GAMM5.540e-9267.28Pyruvate kinase n=1 Tax=Gammaproteobacteria bacter... [more]
A0A1G0FXK3_9GAMM5.700e-9268.66Pyruvate kinase n=1 Tax=Gammaproteobacteria bacter... [more]
A0A2N2ADD0_9GAMM7.400e-9268.04Pyruvate kinase n=2 Tax=Gammaproteobacteria TaxID=... [more]
A0A1G5QJN9_9GAMM2.370e-9066.67Pyruvate kinase n=1 Tax=Thiohalomonas denitrifican... [more]
A0A661BV09_9GAMM2.580e-9066.82Pyruvate kinase n=2 Tax=Gammaproteobacteria bacter... [more]
UPI0018DCB5A92.800e-9067.58pyruvate kinase n=1 Tax=sulfur-oxidizing endosymbi... [more]

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InterPro
Analysis Name: InterProScan on OGS1.0 of Macrocystis pyrifera male
Date Performed: 2022-09-29
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001697Pyruvate kinasePRINTSPR01050PYRUVTKNASEcoord: 55..71
score: 41.81
coord: 11..35
score: 52.43
coord: 36..54
score: 73.04
IPR001697Pyruvate kinasePANTHERPTHR11817PYRUVATE KINASEcoord: 1..215
IPR015795Pyruvate kinase, C-terminalPFAMPF02887PK_Ccoord: 99..213
e-value: 3.5E-34
score: 117.5
IPR015793Pyruvate kinase, barrelPFAMPF00224PKcoord: 1..80
e-value: 5.5E-33
score: 114.3
IPR036918Pyruvate kinase, C-terminal domain superfamilyGENE3D3.40.1380.20coord: 78..212
e-value: 1.7E-70
score: 240.1
IPR036918Pyruvate kinase, C-terminal domain superfamilySUPERFAMILY52935PK C-terminal domain-likecoord: 66..216
IPR040442Pyruvate kinase-like domain superfamilyGENE3D3.20.20.60coord: 1..77
e-value: 1.7E-70
score: 240.1
NoneNo IPR availablePANTHERPTHR11817:SF17PYRUVATE KINASE IIcoord: 1..215
IPR015813Pyruvate/Phosphoenolpyruvate kinase-like domain superfamilySUPERFAMILY51621Phosphoenolpyruvate/pyruvate domaincoord: 1..80

Alignments
The following features are aligned
Aligned FeatureFeature TypeAlignment Location
M-pyrifera_M_contig102364contigM-pyrifera_M_contig102364:6..662 +
Analyses
This polypeptide is derived from or has results from the following analyses
Analysis NameDate Performed
InterProScan on OGS1.0 of Macrocystis pyrifera male2022-09-29
Diamond blastp: OGS1.0 of Macrocystis pyrifera male vs UniRef902022-09-16
OGS1.0 of Macrocystis pyrifera P11B4 male2021-02-24
Relationships

This polypeptide derives from the following mRNA feature(s):

Feature NameUnique NameSpeciesTypePosition
mRNA_M-pyrifera_M_contig102364.506.1mRNA_M-pyrifera_M_contig102364.506.1Macrocystis pyrifera P11B4 malemRNAM-pyrifera_M_contig102364 6..662 +


Sequences
The following sequences are available for this feature:

polypeptide sequence

>prot_M-pyrifera_M_contig102364.506.1 ID=prot_M-pyrifera_M_contig102364.506.1|Name=mRNA_M-pyrifera_M_contig102364.506.1|organism=Macrocystis pyrifera P11B4 male|type=polypeptide|length=219bp
VQKRLIKKARAMNRGIITATQMMESMIENHIPTRAEVFDVANAVIDGTDA
VMLSAETSIGKYPEKVVEAMARICTETEKARGSVGADYRIGQEFADIDET
IAMSTMYAANHLNVKAIVALTETGSTTKWMSRTRSSIPIFAFTRTAKTCR
RVTLFRGVYPFLYDITHSDYLEANKEMIDVLKAHNAVKDGDIVIITKGDL
KGHQGGTNNMKIVKVGELV
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Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001697Pyr_Knase
IPR015795Pyrv_Knase_C
IPR015793Pyrv_Knase_brl
IPR036918Pyrv_Knase_C_sf
IPR040442Pyrv_Kinase-like_dom_sf
IPR015813Pyrv/PenolPyrv_Kinase-like_dom