prot_H-akashiwo_Contig94.22.1 (polypeptide) Heterosigma akashiwo CCMP452

BLAST of mRNA_H-akashiwo_Contig94.22.1 vs. uniprot
Match: A0A7S3Y3M6_HETAK (Hypothetical protein (Fragment) n=1 Tax=Heterosigma akashiwo TaxID=2829 RepID=A0A7S3Y3M6_HETAK)

HSP 1 Score: 810 bits (2091), Expect = 9.300e-292
Identity = 405/417 (97.12%), Postives = 411/417 (98.56%), Query Frame = 0

Query:    1 GVSDYNAYVSAVTELWLMRKSMPKDGMSEGFAAMQKKYCSTKPRDEAIKALLQKLQERTSQRRLDSKEDRGRGTVDDTYTVEQKKSVIPKLVGDKSSLMKVQALSTFNSSSGNFLRCASSRAQNISGLSMVDLNEGVSQSFALVFHADADKITVNGHKSSTAIMRHKDPTQCGIGSITLALMYRWNVLGEKFPNFGVPDEWLTIKLLRSQADNTKPMAYPTVYAHLKTAFLASGILCRNKTHSMRGHAAQKADLEGCSEHHIGRAGKWAPLPQQTAMVKSYLYNLPRPVLRALAGFDPHRATYWLPRADIEPSEELLQLIPQYGLAQEWLQFHTPSEGDTQERRAQMRMDANATIQVIIWFCKVLLQDAVFWMELLPNFELWDRMDVFKSDLFSAYAAAQKTAAVESQDPDLRSLER 417
            GVSDYNAYVSAVTELWLMRKSMPKDGMSEGFAAMQKKYCSTKPRDEAIKALLQKLQERTSQRRLDSKEDRGRGTVDDTYTVEQKKSVIPKLVGDKSSLMK+Q+LS FNSSSGNFLRCASSRAQN+SGLS VDLNEGVSQS+ALVFH+DADKITVNGHKSSTAIMRHKDPTQCGIGSITLALMYRWNVLGEKFPNFGVPDEWLTIKLLRSQADNTKPMAYPTVY H+K AFL SGILCRNKTHSMRGHAAQKADLEGCSEHHIGRAGKWAPLPQQTAMVKSYLYNLPRPVLRALAGFDPHRATYWLPRADIEPSEELLQLIPQY LAQEWLQFHTPSEGDTQERRAQMRMDANATIQVIIWFCKVLLQDAVFWMELLPNFELWDRMDVFKSDLFSAYAAAQKTAAVESQDPDLRSLER
Sbjct:  107 GVSDYNAYVSAVTELWLMRKSMPKDGMSEGFAAMQKKYCSTKPRDEAIKALLQKLQERTSQRRLDSKEDRGRGTVDDTYTVEQKKSVIPKLVGDKSSLMKIQSLSIFNSSSGNFLRCASSRAQNMSGLSKVDLNEGVSQSWALVFHSDADKITVNGHKSSTAIMRHKDPTQCGIGSITLALMYRWNVLGEKFPNFGVPDEWLTIKLLRSQADNTKPMAYPTVYTHIKAAFLGSGILCRNKTHSMRGHAAQKADLEGCSEHHIGRAGKWAPLPQQTAMVKSYLYNLPRPVLRALAGFDPHRATYWLPRADIEPSEELLQLIPQYRLAQEWLQFHTPSEGDTQERRAQMRMDANATIQVIIWFCKVLLQDAVFWMELLPNFELWDRMDVFKSDLFSAYAAAQKTAAVESQDPDLRSLER 523          

BLAST of mRNA_H-akashiwo_Contig94.22.1 vs. uniprot
Match: A0A8H7RTZ3_9FUNG (Uncharacterized protein n=1 Tax=Mucor circinatus TaxID=2054153 RepID=A0A8H7RTZ3_9FUNG)

HSP 1 Score: 125 bits (313), Expect = 3.000e-27
Identity = 112/393 (28.50%), Postives = 175/393 (44.53%), Query Frame = 0

Query:    1 GVSDYNAYVSAVTELWLMRKSMPKDGMSEGFAAMQKKYCSTKPRDEAIKALLQKLQERTSQRRLDSKEDRGRGTVDDTYTVEQKKSVIPKLVGDKSSLMKVQALSTFNSSSGNFLRCASSRAQNISGLSMVDLN------EGVS---QSFALVFHADADKITVNGHKSSTAIMRHKDPTQCGIGSITLALMYRWNVLGEKFPNFGVPDEWLTIKLLRSQ-ADNTKPMAYPTVYAHLKTAFLASGILCRNKTHSMRGHAAQKADLEGCSEHHIGRAGKWAPLPQQTAMVKSYLYNLPRPVLRALAGFDPHRATYWLPRADIEPSEELLQLIPQYGLAQEWLQFHTPSEGDTQERRAQMRMDANATIQVIIWFCKVLLQDAVFWMELLPNFELWD 383
            G S  + YVSA+T L+        + ++ G   M+      +PR  A+K LL+  +    Q+R D+ EDR  GT+ D Y+  +K + +         L K ++    N+     +     R +N+  L + D        EGV+   +  ALV   +  K    G     + +R+ D   C   ++ L L +RW V+ E FPN   P+ W  IKL +    DNTK M     Y  ++  F A  I    KTH+ R   A+ AD+ G  E  I RAG+W       A+  +YL NLPR +LR +AGF      ++L RA  +P  EL   +  + + + W +                 + A+  +Q++     V LQD+V   EL P   +W+
Sbjct:  163 GFSTIDQYVSAITALY-------NEQLTAGVNVME-----NQPRINAVKNLLKNARILDRQKRRDNYEDRAAGTIFDGYSTTEKLAQVVDYF-----LRKDRSEHYRNAMMLLLVHHCLLRGENVRSLDLPDAQTLSLEGEGVTPDIECHALVILINHGKTNKFGKPQYGSCIRNDDIKTCPWMTLALYLFHRWIVVQEPFPNMTKPESWYNIKLCKGDNVDNTKEMQPKAHYDAIEKGFKACHIHSMAKTHAGRQSGAKMADIRGAGESDIRRAGRWT----NDALESAYLTNLPRALLRVMAGFHKDGGRFYLRRAIEKPDPELCHKV--FPMVEVWQERINRGR-----EHGDQSIAADGFLQMLRQLSVVFLQDSVPLQELYPCLSIWN 527          

BLAST of mRNA_H-akashiwo_Contig94.22.1 vs. uniprot
Match: A0A8H7S453_9FUNG (NDC10_II domain-containing protein n=1 Tax=Mucor circinatus TaxID=2054153 RepID=A0A8H7S453_9FUNG)

HSP 1 Score: 115 bits (287), Expect = 3.290e-24
Identity = 107/386 (27.72%), Postives = 169/386 (43.78%), Query Frame = 0

Query:    1 GVSDYNAYVSAVTELWLMRKSMPKDGMSEGFAAMQKKYCSTKPRDEAIKALLQKLQERTSQRRLDSKEDRGRGTVDDTYTVEQKKSVIPKLVGDKSSLMKVQALSTFNSSSGNFLRCASSRAQNISGLSMVDLN-EGVSQSF---ALVFHADADKITVNGHKSSTAIMRHKDPTQCGIGSITLALMYRWNVLGEKFPNFGVPDEWLTIKLLRSQ-ADNTKPMAYPTVYAHLKTAFLASGILCRNKTHSMRGHAAQKADLEGCSEHHIGRAGKWAPLPQQTAMVKSYLYNLPRPVLRALAGFDPHRATYWLPRADIEPSEELLQLIPQYGLAQEWLQFHTPSEGDTQERRAQMRMDANATIQVIIWFCKVLLQDAVFWMELLPNFEL 381
            G S  + YVSA+T L+        + ++ G   M+      +PR  A+K LL+  +    Q+R D+ EDR  GT+ D Y+  +K + +      K      +       S    LR  + R+ ++     + L  EGV+      ALV   D  K    G     + +++ D   C    + L L +RW V+ E F N   P+ W  IKL +    DNTK M     Y  ++  F A  I    KTH+ +   A+ AD+ G  E  I RAG+W       A+  +YL NLPR +LR +AGF      ++L RA  +P  +L + +  + + + W +                 + A+  +Q++     V LQD+V   EL P   +
Sbjct:  163 GFSTIDQYVSAITALY-------NEQLTAGVNVME-----NQPRINAVKNLLKNARILDRQKRCDNYEDRAAGTIFDGYSTTEKLAQVVDYFLRKDRSEHYRNAMMLLLSHHCLLRGENVRSLDLPDAQTLSLEGEGVTPDIECQALVILIDHGKTNKFGKPQYGSCIQNDDIKTCPWMMLALYLFHRWIVVQEPFLNMTKPESWYNIKLYKGDNVDNTKEMQPKAHYDAIEKGFKACHIRSMAKTHAGQQSGAKMADIRGAGESDIRRAGRWT----NDALESAYLTNLPRALLRVMAGFHKDGGRFYLRRAIEKPDPKLCRKV--FPMVEVWQERINRGR-----EHGDQSITADGFLQMLRQLSVVFLQDSVPLQELYPRLSI 525          

BLAST of mRNA_H-akashiwo_Contig94.22.1 vs. uniprot
Match: A0A068REX3_9FUNG (Short-chain dehydrogenase putative n=1 Tax=Lichtheimia corymbifera JMRC:FSU:9682 TaxID=1263082 RepID=A0A068REX3_9FUNG)

HSP 1 Score: 111 bits (277), Expect = 1.230e-22
Identity = 104/381 (27.30%), Postives = 168/381 (44.09%), Query Frame = 0

Query:   43 PRDEAIKALLQKLQERTSQRRLDSKEDRGRGTVDDTYTVEQKKSVIPKLVGDKSSLMKVQALSTFNSSSGNFLRCASSRAQNISGLSMVDLNEGVSQSFALVFHADADKITVNGHKSSTAIMRHKDPTQCGIGSITLALMYRWNVL----GEKFPNFGVPDEWLTIKLLRSQADNTKPMAYPTVYAHLKTAFLASGILCRNKTHSMRGHAAQKADLEGCSEHHIGRAGKWAPLPQQTAMVKSYLYNLPRPVLRALAGFDPHRATYWLPRADIEPSEELLQLIPQYGLAQEWLQFHTPSEGDTQERRAQMRMDANATIQVIIWFCKVLLQDAVFWMEL--LPNFELWDRMDVFKSDLFSAYAAAQKTAAVESQDPDLRSLER 417
            PRD A KA +        QR  D   DRG G++ D YT+++   V      +     + + + TF       LR   +R+  ++ + +    EG ++   LV   D+ K      K   A +RHKD   C +G++ +   YRW +L     E FP F   + W   K+ +     TK + Y T Y  +  AF A  I  ++KTH+ RG  A++A+  G SE ++ R G+W    +  +M   YL N P   +R+L+GF      ++L RA + PSE L Q +  +   + WL        D  +      + A   + +I     V LQD V   +L  L   +L++   +F+   F  +     TA+    +P    L +
Sbjct:  161 PRDAAYKAWIHSFHYEERQRSRDMYIDRGIGSIQDGYTMDEMVKVSEYFFINGQEPHQRERM-TFLLEHVMLLRGDDTRSLELADIFVQFAEEGPTKCPVLVVMLDSGKTNQRHEKQYVAGIRHKDVRICALGAMAIYFFYRWQLLQGKDSENFPTFD-SNRWFDTKVCKG-FHKTKKIHYVTQYRMITKAFNACNIHSKHKTHAGRGSGARQAEAAGVSEDNLKRHGRW----ETGSMGTHYLKNFPFRAIRSLSGFPIDGGQFFLERAVVTPSESLQQKV--FPSVEHWLS----RVQDDDDNDCPQTICAQGFLNLIKELRVVFLQDVVMLRDLPHLSTSKLFNHA-LFEDPEFLQFEQQLLTASRTESNPQQTHLHQ 527          

BLAST of mRNA_H-akashiwo_Contig94.22.1 vs. uniprot
Match: A0A7S3UU98_HETAK (Hypothetical protein n=1 Tax=Heterosigma akashiwo TaxID=2829 RepID=A0A7S3UU98_HETAK)

HSP 1 Score: 110 bits (275), Expect = 2.200e-22
Identity = 83/261 (31.80%), Postives = 130/261 (49.81%), Query Frame = 0

Query:  161 TAIMRHKDPTQCGIGSITLALMYRWNVLGEKFPNFGVPDEWLTIKLLRSQADNTKPMAYPTVYAHLKTAFLASGILCRNKTHSMRGHAAQKADLEGCSEHHIGRAGKWAPLPQQTAMVKSYLYNLPRPVLRALAGFDPHRATYWLPRADIEPSEELLQLIPQYGLAQEWLQFHTPSEGDTQERRAQMRMDANATIQVIIWFCK-------VLLQDAVFWMELLPNFELWDRMDVFKSDLFSAYAAAQKTAAVESQDPDLRS 414
            + ++RH++P  CG G   L    ++++LGE FP       WL   +     DN + ++Y  +Y      +    +  + KTH +R  AA+ A++ GCSE  + RAG W        + +SYL NLP   L+ALAGF      ++LPR  IEP +EL  L+  +  A  WL+ H   EG         +++    +   I FCK       +LLQDA   ME  P  E+W    +F+   FS++AA Q+  A+ ++ P++ S
Sbjct:    4 SGMLRHRNPELCGWGGFALHEFEKYHILGEPFPLMDKKQGWLQKPVY--SGDNGERISYFQMYNGASKCWEKVELTSQKKTH-VRAAAARMANMLGCSEEALERAGNWGT----DVLEQSYLTNLPLEALKALAGFAKDE-DHFLPRDLIEPPKELAALL--WPEADRWLKKH--QEG---------KVEGGKPVMAAIGFCKLMIKTRKILLQDAAILMERYPLLEIWQH-PIFQCASFSSFAAQQR--AIIARTPEVYS 240          

BLAST of mRNA_H-akashiwo_Contig94.22.1 vs. uniprot
Match: A0A8H7VP47_9FUNG (Uncharacterized protein n=1 Tax=Mucor circinatus TaxID=2054153 RepID=A0A8H7VP47_9FUNG)

HSP 1 Score: 109 bits (273), Expect = 2.400e-22
Identity = 108/378 (28.57%), Postives = 164/378 (43.39%), Query Frame = 0

Query:    1 GVSDYNAYVSAVTELWLMRKSMPKDGMSEGFAAMQKKYCSTKPRDEAIKALLQKLQERTSQRRLDSKEDRGRGTVDDTY-TVEQKKSVIPKLVGDKSSLMKVQALSTFNSSSGNFLRCASSRAQNISGLSMVDLNEGVSQSFALVFHADADKITVNGHKSSTAIMRHKDPTQCGIGSITLALMYRWNVLGEKFPNFGVPDEWLTIKLLRSQ-ADNTKPMAYPTVYAHLKTAFLASGILCRNKTHSMRGHAAQKADLEGCSEHHIGRAGKWAPLPQQTAMVKSYLYNLPRPVLRALAGFDPHRATYWLPRADIEPSEELLQLIPQYGLAQEWLQFHTPSEGDTQERRAQMR------MDANATIQVIIWFCKVLLQDAV 370
            G S  + YVSA+T L+        + ++ G   M+      +PR  A+K LL+  +    Q+R D+ EDR  GT+ D Y T+E+   V+   +    S     A+    S       C S R +N+  L +                 DA  +++ G   +  I  H     C   ++ L L + W V+ E FPN   P+ W  IKL +    DNTK M     Y  ++  F A  I    KTH+ R   A+ AD+ G  E  I RAG W       A+  +YL NLPR +LR +AGF      ++L  A  +P  +L + +  + + + W           QER  Q R      + A+  +Q++     V LQD+V
Sbjct:  205 GFSTIDQYVSAITALY-------NEQLTAGVNVME-----NQPRINAVKKLLKNARVLDQQKRRDNYEDRAAGTIFDGYSTIEKLAQVVDYFLRKDQSEHYQNAMMLLLSH-----HCLS-RGKNLHSLDL----------------PDAQTLSLEGEGVTPNIECHALIKTCPWMTLALYLFHCWTVVQEPFPNMTKPESWYNIKLCKGDNVDNTKEMQPKAHYDAIEKGFKACHIHSMTKTHAGRQSGAKMADIRGAGESDIRRAGHWT----NDALESAYLTNLPRALLRVMAGFHKDGGRFYLRHAIEKPDPKLCRKV--FPMVKVW-----------QERINQGRDHGDQSIAADGFLQMLRQLSIVFLQDSV 531          

BLAST of mRNA_H-akashiwo_Contig94.22.1 vs. uniprot
Match: A0A8H7VLL9_9FUNG (NDC10_II domain-containing protein n=1 Tax=Mucor circinatus TaxID=2054153 RepID=A0A8H7VLL9_9FUNG)

HSP 1 Score: 104 bits (260), Expect = 9.380e-22
Identity = 69/208 (33.17%), Postives = 106/208 (50.96%), Query Frame = 0

Query:  114 FLRCASSRAQNISGL-SMVDLNEGVSQSFALVFHADADKITVNGHKSSTAIMRHKDPTQCGIGSITLALMYRWNVLGEKFPNFGVPDEWLTIKLLRSQADNTKPMAYPTVYAHLKTAFLASGILCRNKTHSMRGHAAQKADLEGCSEHHIGRAGKWAPLPQQTAMVKSYLYNLPRPVLRALAGFDPHRATYWLPRADIEPSEELLQLI 320
            FLR  S R    + L SM+   EG ++ +ALV      K    G     A +R+++   C   +++  L +RW++ GE F +     +W  +KL++S AD T  ++Y      + +AF   G+  + KTH+MRG  A+ A+  G SE  I R G+W       A+ K YL N+PR VLR LAGF      ++L  A + P  EL + +
Sbjct:   79 FLRGESIRMMEFADLQSMLLEREGATECYALVMVLLQGKTNQEGRVEFAACIRNRNVEICPQMTLSFYLFHRWHIQGEPFSSLNQNKDWYRLKLIKS-ADLTVELSYSQHLDAISSAFKEIGLHSKAKTHAMRGSGARMAEQLGTSESFIQRLGRW----NSNALSKKYLTNVPREVLRTLAGFTAEAGQFYLSCAAVIPPPELCRKV 281          

BLAST of mRNA_H-akashiwo_Contig94.22.1 vs. uniprot
Match: A0A177U7H3_9BASI (NDC10_II domain-containing protein n=1 Tax=Tilletia walkeri TaxID=117179 RepID=A0A177U7H3_9BASI)

HSP 1 Score: 91.7 bits (226), Expect = 3.980e-16
Identity = 79/258 (30.62%), Postives = 118/258 (45.74%), Query Frame = 0

Query:  165 RHKDPTQCGIGSITLALMYRWNVLGEKFPNFGVPDEWLTIKLLRSQA--DNTKPMAYPTVYAHLKTAFLASGILCRNKTHSMRGHAAQKADLEGCSEHHIGRAGKWAPLPQQTAMVKSYLYNLPRPVLRALAGFDPHRATYWLPRADIEPSEELLQLIPQYGLAQEWLQFHTPSEGDTQERRAQMRMDANATIQVI--IWFCKV-LLQDAVFWMELLPNFELWDRMDVFKSDLFSAYAAAQKTAAVESQDPDLRSLER 417
            RHKD   C +GS  + L  R++   E  PNF   + W   KLL ++   + T  + Y T  A LK AF +  I     TH+MR   ++ A   GC+E  + + G+W        M++ YL  +    +RAL+GF      YWLPRA +EP +EL Q I        W++   PS    Q R        +A ++ +  + F +V LLQDA    +  P+  L+     F +  FS Y  +  T    +  P    LE+
Sbjct:  278 RHKDVEVCSVGSFAIYLFARFHCEKEAPPNFAARETWYKTKLLVAEGCLEPTIAITYETQSALLKQAFSSCAITSSALTHAMRRGGSRVAYEAGCTEDDVRKHGRWCG----DRMMERYLTGVSIQPVRALSGFKIEGGDYWLPRALLEPPQELAQSIFP------WVE---PSYKQIQARVLVGGKSDSAALEFLTMLKFLRVVLLQDAAILQDQCPSPFLFSYAP-FNTKAFSNYQTSLLTKINSTPTPFDMQLEQ 521          

BLAST of mRNA_H-akashiwo_Contig94.22.1 vs. uniprot
Match: A0A177T8E9_9BASI (NDC10_II domain-containing protein n=1 Tax=Tilletia indica TaxID=43049 RepID=A0A177T8E9_9BASI)

HSP 1 Score: 90.5 bits (223), Expect = 1.020e-15
Identity = 74/256 (28.91%), Postives = 115/256 (44.92%), Query Frame = 0

Query:  165 RHKDPTQCGIGSITLALMYRWNVLGEKFPNFGVPDEWLTIKLLRSQA--DNTKPMAYPTVYAHLKTAFLASGILCRNKTHSMRGHAAQKADLEGCSEHHIGRAGKWAPLPQQTAMVKSYLYNLPRPVLRALAGFDPHRATYWLPRADIEPSEELLQLI-PQYGLAQEWLQFHTPSEGDTQERRAQMRMDANATIQVIIWFCKVLLQDAVFWMELLPNFELWDRMDVFKSDLFSAYAAAQKTAAVESQDPDLRSLER 417
            RHKD   C +GS  + L  R++   E  PNF   + W   KLL ++   + T  + Y T  A LK AF +  I     TH+MR   ++ A   GC+E  + + G+W        M++ YL  +    +RAL+GF      YWLPRA +EP +EL Q I P    + + +Q      G++     +        + ++ +   VLLQDA    +  P+  L+     F +  F  Y  +  T    +  P    LE+
Sbjct:  418 RHKDVEVCSVGSFAIYLFARFHCEKEAPPNFAARETWYKTKLLVAEGCLEPTIAITYETQSALLKQAFSSCAITSSALTHAMRRGGSRVAYEAGCTEDGVRKHGRWCG----DRMMERYLTGVSIQPVRALSGFKIEGGDYWLPRALLEPPQELAQSIFPWVEPSYKQIQARVLVGGESDSAALEF-------LTMLKFLRVVLLQDAAILQDQYPSLFLFSYAP-FNTKAFFNYQTSLLTKINSTPTPFDMQLEQ 661          

BLAST of mRNA_H-akashiwo_Contig94.22.1 vs. uniprot
Match: J8TRY1_TRIAS (Transposable element-crypton-Cn1 n=1 Tax=Trichosporon asahii var. asahii (strain ATCC 90039 / CBS 2479 / JCM 2466 / KCTC 7840 / NBRC 103889/ NCYC 2677 / UAMH 7654) TaxID=1186058 RepID=J8TRY1_TRIAS)

HSP 1 Score: 88.6 bits (218), Expect = 4.070e-15
Identity = 79/328 (24.09%), Postives = 144/328 (43.90%), Query Frame = 0

Query:    6 NAYVSAVTELWLMRKSMPKDGMSEGFAAMQKKYCSTKPRDEAIKALLQKLQERTSQRRLDSKEDRGRGTVDDTYTVEQK-KSVIPKLVGDKSSLMKVQALSTFNSSSGNFLRCASSRAQNISGLSMVDLNEGVSQSFALVFHADADKITVN--GHKSSTAIMRHKDPTQCGIGSITLALMYRWNVLGE-------KFPNFGVPDEWLTIKLLRSQADNTKPMAYPTVYAHLKTAFLASGILCRNKTHSMRGHAAQKADLEGCSEHHIGRAGKWAPLPQQTAMVKSYLYNLPRPVLRALAGFDPHRAT-YWLPRADIEPSEELLQLIPQ 322
            + ++ A+ +LW ++ +    G++           +  PR   +KAL   +      R +    D GRG + D +T  Q+ +      + + +S   ++     +++    +RC       +    M ++    S +   VF+A  +    N  G     +++RH+D + C +  + L L  R++ +GE        FP+    + W    +  S  ++ +P+ Y T       A   + +    KTH MR   A++A+  GC+E  I + G+W    Q   M   YL ++ RPVL A+AGF+P   T Y+LPRA   P     ++ PQ
Sbjct:  194 DTWICAIVDLWSIQSNK---GINR----------NAHPRMGPVKALTFAITRLQRARDIYYSVDPGRGGIMDGFTTHQQLRDFFDYFMYESNSPEGIRDAFLCSTAIAGMMRCDEYAKTRLMDWGMYEMENDTSATPFRVFYATLNHGKNNQFGKTEYASMLRHRDVSMCPVAFLALHLYVRFHHMGETFEHSDDNFPSMAKREHWYKEYMAPSPRNSQEPLPYQTHLDAFGKALAYAKVATAQKTHLMRKTGARRAEAAGCTEAQICKHGRWKNGTQ--VMENVYLTHMSRPVLHAMAGFNPELHTDYYLPRAVPVPDNLQRKVFPQ 506