prot_H-akashiwo_Contig94.14.1 (polypeptide) Heterosigma akashiwo CCMP452

You are viewing a polypeptide, more information available on the corresponding mRNA page

Overview
NamemRNA_H-akashiwo_Contig94.14.1
Unique Nameprot_H-akashiwo_Contig94.14.1
Typepolypeptide
OrganismHeterosigma akashiwo CCMP452 (Heterosigma akashiwo CCMP452)
Sequence length251
Homology
BLAST of mRNA_H-akashiwo_Contig94.14.1 vs. uniprot
Match: A0A6H5JQN7_9PHAE (Kin17_mid domain-containing protein n=2 Tax=Ectocarpus TaxID=2879 RepID=A0A6H5JQN7_9PHAE)

HSP 1 Score: 110 bits (275), Expect = 3.300e-24
Identity = 110/271 (40.59%), Postives = 140/271 (51.66%), Query Frame = 0
Query:    1 MNSTKWETLTVFIKYLGKKGAIVADQTERGWFIQWIDRDPETLRRQALAEKRQKADKEEADDVSQATASVHDQADDDDTTQAGEVLAVEGTSEEQRRSSPLPTKPA--------VDRGRTPPVATTTRPATELTGRSRPLVRTPGRTGGARAACCVAREARRGA-ERGRASSRFKAGAV---AHGAKMSALDQLMEQDKXXXXXXXXXXXXXXXXM--------ARKDYWLARGIIVKILNKKVGGGKYYKKKARVSKVIERYVGEVSKVD 251
            MNST WETLT F+ YLGK    V D+TE+GW+IQW+DRDP  L  Q  A +RQK+D ++ +  ++A       A   D  +A    A  G +E +R       +          V  G +    TT                     GG      + R    GA   G A      G V     GAK S ++ +M    XXXXXXXXXXXXXXXX         +RKDYWL +GI+VK++NK+VGGGKYYKKKAR+ KV+ERYVGEV  +D
Sbjct:  141 MNSTHWETLTSFVLYLGKVKKAVVDETEKGWYIQWVDRDPRLLAMQEAAARRQKSDLDDEEKQARAIEKQIQAAKARDEGRADTDAAAAGPTELRREEGQASLRIGLKSRAQTFVPGGGSGSDLTTAXXXXXXXXXXXXXXXXXXXXGG-----LLKRPKLSGAFGEGGAXXXXXXGPVKGKGKGAKRSVMEVMMXXXXXXXXXXXXXXXXXXXXXXEVKAKDSSRKDYWLRQGIVVKVMNKRVGGGKYYKKKARLRKVVERYVGEVKMID 406          
BLAST of mRNA_H-akashiwo_Contig94.14.1 vs. uniprot
Match: A0A1Y1ILP0_KLENI (Kin17_mid domain-containing protein n=1 Tax=Klebsormidium nitens TaxID=105231 RepID=A0A1Y1ILP0_KLENI)

HSP 1 Score: 107 bits (266), Expect = 3.000e-23
Identity = 89/256 (34.77%), Postives = 121/256 (47.27%), Query Frame = 0
Query:    1 MNSTKWETLTVFIKYLGKKGAIVADQTERGWFIQWIDRDPETLRRQALAEKRQKADKEEADDVSQ-ATASVHDQADDDDTTQAGEVLAVEGTSEEQRRSSPLPTKPAVDRGRTPPVATTTRPATELTGRSRPLVRTPG-RTGGARAACCVAREARRGAE---RGRASSRFKAGAVAHGAKMSALDQLMEQDKXXXXXXXXXXXXXXXXMARKDYWLARGIIVKILNKKVGGGKYYKKKARVSKVIERYVGEVSKVD 251
            MNSTKW TL+ F+KYLGK G +  + T +GWFI ++DR+PET+ R+A  EKR+KA+  E D   +   A V   A    T   G   A   T++E RR      K A   G +              G  RP  + P  +   +R A   A E  R  E   RGR     K G       +SA+ Q  E+ K                + RKDYWL  GI+VK++++ +    YYK K  V  VI +Y+GE+  VD
Sbjct:  106 MNSTKWLTLSDFVKYLGKTGQVKVEDTPKGWFITYVDREPETIMREASKEKRKKAELAEEDRHDRDLLAQVERAAKQQKTAPDGGEAAEAATAKELRRDEATGEKIAFAMGGS-------------NGTKRPAEKAPAEKASTSRPAIFAAEEESRAPETSGRGREGGAAKGGEKGREDTLSAMMQEQERAKER--------------LNRKDYWLTTGIVVKVMSRALKEKGYYKMKGVVKAVIAKYIGEIEMVD 334          
BLAST of mRNA_H-akashiwo_Contig94.14.1 vs. uniprot
Match: UPI000719E667 (DNA/RNA-binding protein KIN17-like n=1 Tax=Priapulus caudatus TaxID=37621 RepID=UPI000719E667)

HSP 1 Score: 103 bits (258), Expect = 3.840e-22
Identity = 88/256 (34.38%), Postives = 128/256 (50.00%), Query Frame = 0
Query:    1 MNSTKWETLTVFIKYLGKKGAIVADQTERGWFIQWIDRDPETLRRQALAEKRQKADKEEADDVSQATASVHDQADDDDTTQAGEVLA---VEGTSEEQRRSSPLPTK-PAVDRGRTPPVATTTRPATELTG-RSRPLVRTPGRTGGARAACCVAREARRGAERGRASSRFKAGAVAHGAKMSALDQLMEQDKXXXXXXXXXXXXXXXXMARKDYWLARGIIVKILNKKVGGGKYYKKKARVSKVIERYVGEVSKVD 251
            MNST+WETLT F+K+LG++G    D TE+GWFI WIDRDPET+RRQ     ++K D ++ + +S+      ++  +     A E +    ++  SEE++    LP       + R P    +  P   LT  R +PL                          G+A S+ K  A A   K SALD++ME ++                M RK YWL  GI+VKI+ +K+G  KYYKKKA V +V+E++   V  +D
Sbjct:  109 MNSTQWETLTDFVKWLGREGHCNVDHTEKGWFITWIDRDPETIRRQEQLAAKRKMDMDDEERMSRFIQKQVERVQEQKKHSAEEEVEHTELKRQSEEEKVVFKLPASLSGGGKPREPTDEPSLPPENPLTSTRQKPLT---------------------AESSGKARSKPKEAAAAQKRK-SALDEIMEFEEQSKEK-----------MNRKSYWLTEGIVVKIITRKLGE-KYYKKKAVVREVVEQFGAVVKMLD 330          
BLAST of mRNA_H-akashiwo_Contig94.14.1 vs. uniprot
Match: UPI00201F0909 (DNA/RNA-binding protein KIN17-like n=2 Tax=Haliotis TaxID=6452 RepID=UPI00201F0909)

HSP 1 Score: 103 bits (257), Expect = 4.980e-22
Identity = 84/253 (33.20%), Postives = 128/253 (50.59%), Query Frame = 0
Query:    1 MNSTKWETLTVFIKYLGKKGAIVADQTERGWFIQWIDRDPETLRRQALAEKRQKADKEEADDVSQATASVHDQADDDDTTQAG-EVLAVEGTSEEQRRSSPLPTKPAVDRGRTPPVATTTRPATELTGRSRPLVRTPGRTGGARAACCVAREARRGAERGRASSRFKAGAVAHGAKM-SALDQLMEQDKXXXXXXXXXXXXXXXXMARKDYWLARGIIVKILNKKVGGGKYYKKKARVSKVIERYVGEVSKVD 251
            MNST WETLT F+K+LGK+G  V D TE+GWF+Q+IDRDPET+RRQ   + ++K D ++ +  ++       +A   DT     E   ++   EE++ +  L      D G      TT +  T       PL +   ++   +             E  R   + + GA   G K  SAL ++ME ++                + RKDYWL +GI++KI++KK+G  K+YKKKA V +V + Y G +  +D
Sbjct:  109 MNSTMWETLTEFVKWLGKEGECVVDYTEKGWFVQYIDRDPETIRRQEATKAKEKMDMDDEERTAKFIKQQISRASQSDTKSHNPEFTELKREDEEEKVTFSL------DSGAKKTEDTTFKKPT-----GNPLKKVDSKSVFGKG------------ESSRQEGKMETGAEMRGQKRKSALGEIMEFEEKKREK-----------VNRKDYWLQKGIVIKIVSKKLGD-KFYKKKAYVKEVKDLYTGIIKTLD 326          
BLAST of mRNA_H-akashiwo_Contig94.14.1 vs. uniprot
Match: A0A210PJB4_MIZYE (DNA/RNA-binding protein KIN17 n=3 Tax=Pectinidae TaxID=6566 RepID=A0A210PJB4_MIZYE)

HSP 1 Score: 103 bits (257), Expect = 5.080e-22
Identity = 81/252 (32.14%), Postives = 133/252 (52.78%), Query Frame = 0
Query:    1 MNSTKWETLTVFIKYLGKKGAIVADQTERGWFIQWIDRDPETLRRQALAEKRQKADKEEADDVSQ-ATASVHDQADDDDTTQAGEVLAVEGTSEEQRRSSPLPTKPAVDRGRTPPVATTTRPATELTGRSRPLVRTPGRTGGARAACCVAREARRGAERGRASSRFKAGAVAHGAKMSALDQLMEQDKXXXXXXXXXXXXXXXXMARKDYWLARGIIVKILNKKVGGGKYYKKKARVSKVIERYVGEVSKVD 251
            MNST+WETLT F+K+LG++G  V D+TE+GWF+ +IDR+PE +RRQ   + ++K D  + +  S+     +   A+ D T++A E    +  +EE++ +  L    ++ + +   V  +T     +          P  +G ++     + + R   + G A  + K          SALD++ME ++                M RKDYWL +GI+VK++ KK+G  KYYKKKA V +VI+ Y G +  +D
Sbjct:  109 MNSTQWETLTEFVKWLGREGKCVVDETEKGWFVAYIDRNPEAIRRQEQVKAKEKMDLTDEERTSKFIQQQIVRAAEKDTTSKAAEFTEFKRENEEEKVTMSLS---SLVKKKEEKVKISTDNLFTIP---------PDSSGSSKGESSTSSQKREATKPGLAGQKRK----------SALDEIMEFEEKKKEK-----------MNRKDYWLHKGIVVKVVTKKLGE-KYYKKKAFVKEVIDLYKGVIKVID 326          
BLAST of mRNA_H-akashiwo_Contig94.14.1 vs. uniprot
Match: A0A662WSG2_9STRA (Kin17_mid domain-containing protein n=1 Tax=Nothophytophthora sp. Chile5 TaxID=2483409 RepID=A0A662WSG2_9STRA)

HSP 1 Score: 104 bits (260), Expect = 6.820e-22
Identity = 97/251 (38.65%), Postives = 139/251 (55.38%), Query Frame = 0
Query:    1 MNSTKWETLTVFIKYLGKKGAIVADQTERGWFIQWIDRDPETLRRQALAEKRQKADKEEADDVSQATASVHDQADDDDTTQAGEVLAVEGTSEEQRRSSPLPTKPAVDRGRTPPVATTTRPATELTGRSRPLVRTPGRTGGARAACCVAREARRGAERGRASSRFKAGAVAHGAKMSALDQLMEQDKXXXXXXXXXXXXXXXXMARKDYWLARGIIVKILNKKVGGGKYYKKKARVSKVIERYVGEVSKVD 251
            MN+T+WETL  F++YLG+ G  V D+TE+GW IQ+IDRDP  + RQ   EK++KA   E D   +  A +          Q     +V G  EE+    P   +   D G    ++  T+PA +    +  + R    +  A  +     +    +  GRA  R  A +V    K +A+D +M ++ XXXXXXXXXXXXXXXX  RK+ W+A+GI+VK+ NKKVGGG YYK+K  VS V +++   V  +D
Sbjct:  557 MNATQWETLGTFVQYLGRTGKCVVDETEKGWHIQYIDRDPRAIARQEELEKKKKA---ELDHEERNDAFIK--------RQLKIAQSVAGQQEEEEAQRPTKLR-RTDSGAKITISLATKPAAKENNSASSIARAAAFS--AAGSNVFEGDGDSASSYGRAEKRNVAESVGQRRKRNAVDAIMAEEXXXXXXXXXXXXXXXXXX-RKENWIAKGIVVKVTNKKVGGGSYYKQKGVVSAVEDKFCATVKLLD 792          
BLAST of mRNA_H-akashiwo_Contig94.14.1 vs. uniprot
Match: A0A1S3H5D1_LINUN (DNA/RNA-binding protein KIN17 n=1 Tax=Lingula unguis TaxID=7574 RepID=A0A1S3H5D1_LINUN)

HSP 1 Score: 102 bits (255), Expect = 9.090e-22
Identity = 79/252 (31.35%), Postives = 132/252 (52.38%), Query Frame = 0
Query:    1 MNSTKWETLTVFIKYLGKKGAIVADQTERGWFIQWIDRDPETLRRQALAEKRQKADKEEADDVSQATASVHDQADDDDTTQA-GEVLAVEGTSEEQRRSSPLPTKPAVDRGRTPPVATTTRPATELTGRSRPLVRTPGRTGGARAACCVAREARRGAERGRASSRFKAGAVAHGAKMSALDQLMEQDKXXXXXXXXXXXXXXXXMARKDYWLARGIIVKILNKKVGGGKYYKKKARVSKVIERYVGEVSKVD 251
            MNST+WETLT F+K+LGK G+ V D+TE+GWF+Q+IDRDPET+RRQ   + ++K + ++ + V++      ++A + +  Q   E   ++  SEE++ +  L              A   +   +   +S P +               A E +      + S   K+ + A   + +ALD++ME ++                M RKDYWL +GI+VK++ KK+G  K+YKKK  V +V+++Y G +  +D
Sbjct:  108 MNSTQWETLTEFVKHLGKDGSCVVDETEKGWFVQYIDRDPETIRRQEALKSKEKMELDDEEKVARFIQKQIERAAETEKEQPKSEYTELKRESEEEKVAFNL--------------AAMKKSEGKSAVKSLPSMN-----------ALKAEEKKHAPTTSKDS--LKSTSTAGQKRKNALDEIMEFEEQKKEK-----------MNRKDYWLHKGIVVKVVTKKLGD-KFYKKKGVVKEVVDQYAGVIKMLD 320          
BLAST of mRNA_H-akashiwo_Contig94.14.1 vs. uniprot
Match: A0A1B0CZ67_PHLPP (Kin17_mid domain-containing protein n=1 Tax=Phlebotomus papatasi TaxID=29031 RepID=A0A1B0CZ67_PHLPP)

HSP 1 Score: 99.4 bits (246), Expect = 8.240e-21
Identity = 81/256 (31.64%), Postives = 126/256 (49.22%), Query Frame = 0
Query:    1 MNSTKWETLTVFIKYLGKKGAIVADQTERGWFIQWIDRDPETLRRQALAEKRQKADKEEADDVSQATASVHDQADDDDTTQAGEVLAVEGTSEEQRRSSP---------LPTKPAVDRGRTPPVATTTRPATELTGRSRPLVRTPGRTGGARAACCVAREARRGAERGRASSRFKAGAVAHGAKMSALDQLMEQDKXXXXXXXXXXXXXXXXMARKDYWLARGIIVKILNKKVGGGKYYKKKARVSKVIERYVGEV 247
            MN+TKW +LT F+ +LGK G  V D+TE+GW+I +IDRDPET+ RQ    K+QK DK   DD  +    +  Q +       G   A E   +E  R S          L TK   +       A   +P+++       L + P  + G+              + G+   +     +A G ++SALD++++ ++                  RKDYWLA GI+VKI+++ +  GKYYK+KA V+K+I++Y  +V
Sbjct:   50 MNATKWLSLTGFVLWLGKTGQCVVDETEKGWYITYIDRDPETVARQEKMAKKQKMDK---DDEERLQEFIEKQVERGKKDSPGHSSAAEDRVQEFVRESEDEKIKLNINLATKKKSE-------AVFKKPSSDF------LSKRPSSSSGS--------------DNGKKQKKD----IADGRRVSALDEIIKIEESKKERSN-----------RKDYWLAEGIVVKIVSQSLSEGKYYKQKAHVTKIIDKYEAKV 260          
BLAST of mRNA_H-akashiwo_Contig94.14.1 vs. uniprot
Match: A0A182GPQ7_AEDAL (Kin17_mid domain-containing protein n=4 Tax=Stegomyia TaxID=53541 RepID=A0A182GPQ7_AEDAL)

HSP 1 Score: 99.0 bits (245), Expect = 2.170e-20
Identity = 83/251 (33.07%), Postives = 124/251 (49.40%), Query Frame = 0
Query:    1 MNSTKWETLTVFIKYLGKKGAIVADQTERGWFIQWIDRDPETLRRQALAEKRQKADKEEADDVSQATASVHDQADDDDTTQAGEVLAVEGTSEEQRRSSPLPTKPAVDRGRTPPVATTTRPATELTGRSRP--LVRTPGRTGGARAACCVAREARRGAERGRASSRFKAGAVAHGA--KMSALDQLMEQDKXXXXXXXXXXXXXXXXMARKDYWLARGIIVKILNKKVGGGKYYKKKARVSKVIERYVGEV 247
            MNSTKW +L+ F+K+LG+ G  VAD+TE+GWFI +IDRDPETL  Q    K+QK DK++ + +++                  E     G  EE+  SS   T+   D      +    +  T +   S+P  L + P  T                A+  R   +FK G+ + G   K SALD+L+ +++                  RKDYWLA GI+VK+++K +G  K+YK+K  V  VI+RY  ++
Sbjct:  109 MNSTKWHSLSEFVKFLGRNGHCVADETEKGWFITYIDRDPETLAMQEKMAKKQKMDKDDEERLAEFI----------------EEQVRRGHKEEEPSSSTSYTELKRD-NEEETIKLNLKLGTTIKVESKPIKLEKRPFETA---------------ADEDRKEKKFKPGSSSSGVFKKPSALDELIREEEIKKEKTN-----------RKDYWLAEGIVVKLVSKSLGE-KFYKEKGVVLDVIDRYRAKI 315          
BLAST of mRNA_H-akashiwo_Contig94.14.1 vs. uniprot
Match: KIN17_ARATH (KIN17-like protein n=10 Tax=Camelineae TaxID=980083 RepID=KIN17_ARATH)

HSP 1 Score: 99.0 bits (245), Expect = 2.590e-20
Identity = 84/259 (32.43%), Postives = 125/259 (48.26%), Query Frame = 0
Query:    1 MNSTKWETLTVFIKYLGKKGAIVADQTERGWFIQWIDRDPETLRRQALAEKRQKADKEEAD--------DVSQATASVHDQADDDDTTQAGEVLAVEGTSEEQRRSSPLPTKPAVDRGRTPPVATTTRPATELTGRSRPLVRTPGRTGGARAACCVAREARRGAERGRASSRFKAGAVAHGAKMSALDQLMEQDKXXXXXXXXXXXXXXXXMARKDYWLARGIIVKILNKKVGGGKYYKKKARVSKVIERYVGEVSKVD 251
            MNST+W TLT FIK+LGK G    ++T +GWFI +IDRD ETL ++ L  KR K+D  E +         + +A   ++    + +T+   EV  V+   +E+++   L  K  V  G              L G  + +    G+  G  +      E     ERG    R      +   + SALD+LM++++                M RKDYWL  GIIVK+++K +    YYK+K  V KVI+ YVGE+  +D
Sbjct:  107 MNSTEWATLTEFIKHLGKTGKCKVEETPKGWFITYIDRDSETLFKERLKNKRVKSDLAEEEKQEREIQRQIERAAEKLNGGGGEGETSGNDEV--VDDGDDERKKDEDLRLKSGVKVG------------FALGGGVKQVA--TGKERGESSKLLFGDEENDKVERGEKRKRSGDSGRSEKERRSALDELMKEEEKKKER-----------MNRKDYWLFEGIIVKVMSKALAEKGYYKQKGVVKKVIDNYVGEIKMLD 338          
The following BLAST results are available for this feature:
BLAST of mRNA_H-akashiwo_Contig94.14.1 vs. uniprot
Analysis Date: 2022-09-16 (Diamond blastp: OGS1.0 vs UniRef90)
Total hits: 25
Match NameE-valueIdentityDescription
A0A6H5JQN7_9PHAE3.300e-2440.59Kin17_mid domain-containing protein n=2 Tax=Ectoca... [more]
A0A1Y1ILP0_KLENI3.000e-2334.77Kin17_mid domain-containing protein n=1 Tax=Klebso... [more]
UPI000719E6673.840e-2234.38DNA/RNA-binding protein KIN17-like n=1 Tax=Priapul... [more]
UPI00201F09094.980e-2233.20DNA/RNA-binding protein KIN17-like n=2 Tax=Halioti... [more]
A0A210PJB4_MIZYE5.080e-2232.14DNA/RNA-binding protein KIN17 n=3 Tax=Pectinidae T... [more]
A0A662WSG2_9STRA6.820e-2238.65Kin17_mid domain-containing protein n=1 Tax=Nothop... [more]
A0A1S3H5D1_LINUN9.090e-2231.35DNA/RNA-binding protein KIN17 n=1 Tax=Lingula ungu... [more]
A0A1B0CZ67_PHLPP8.240e-2131.64Kin17_mid domain-containing protein n=1 Tax=Phlebo... [more]
A0A182GPQ7_AEDAL2.170e-2033.07Kin17_mid domain-containing protein n=4 Tax=Stegom... [more]
KIN17_ARATH2.590e-2032.43KIN17-like protein n=10 Tax=Camelineae TaxID=98008... [more]

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InterPro
Analysis Name: InterProScan on OGS1.0
Date Performed: 2022-09-29
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR019447DNA/RNA-binding protein Kin17, WH-like domainSMARTSM01253Kin17_mid_2coord: 1..65
e-value: 2.8E-9
score: 25.9
IPR019447DNA/RNA-binding protein Kin17, WH-like domainPFAMPF10357Kin17_midcoord: 1..61
e-value: 8.3E-19
score: 67.7
IPR038254DNA/RNA-binding protein KIN17, WH-like domain superfamilyGENE3D1.10.10.2030coord: 1..54
e-value: 1.8E-17
score: 65.0
IPR041330KN17, SH3-like C-terminal domainPFAMPF18131KN17_SH3coord: 206..248
e-value: 3.9E-15
score: 55.6
NoneNo IPR availableGENE3D2.30.30.140coord: 214..251
e-value: 2.2E-8
score: 36.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 46..138
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 46..78
IPR037321KIN17-like proteinPANTHERPTHR12805KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOGcoord: 1..250

Alignments
The following features are aligned
Aligned FeatureFeature TypeAlignment Location
H-akashiwo_Contig94contigH-akashiwo_Contig94:658096..695336 +
Analyses
This polypeptide is derived from or has results from the following analyses
Analysis NameDate Performed
InterProScan on OGS1.02022-09-29
Diamond blastp: OGS1.0 vs UniRef902022-09-16
Heterosigma akashiwo CCMP452 OGS1.02022-07-08
Relationships

This polypeptide derives from the following mRNA feature(s):

Feature NameUnique NameSpeciesTypePosition
mRNA_H-akashiwo_Contig94.14.1mRNA_H-akashiwo_Contig94.14.1Heterosigma akashiwo CCMP452mRNAH-akashiwo_Contig94 637083..695336 +


Sequences
The following sequences are available for this feature:

polypeptide sequence

>prot_H-akashiwo_Contig94.14.1 ID=prot_H-akashiwo_Contig94.14.1|Name=mRNA_H-akashiwo_Contig94.14.1|organism=Heterosigma akashiwo CCMP452|type=polypeptide|length=251bp
MNSTKWETLTVFIKYLGKKGAIVADQTERGWFIQWIDRDPETLRRQALAE
KRQKADKEEADDVSQATASVHDQADDDDTTQAGEVLAVEGTSEEQRRSSP
LPTKPAVDRGRTPPVATTTRPATELTGRSRPLVRTPGRTGGARAACCVAR
EARRGAERGRASSRFKAGAVAHGAKMSALDQLMEQDKKRKAAAAAAEQVY
EEEMARKDYWLARGIIVKILNKKVGGGKYYKKKARVSKVIERYVGEVSKV
D
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Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR019447DNA/RNA-bd_Kin17_WH-like_dom
IPR038254KIN17_WH-like_sf
IPR041330KN17_SH3
IPR037321KIN17-like