EsuBft1350_5 (polypeptide) Ectocarpus subulatus male Bft15b

Query:    1 MPNPLQKHDMFSATRRAHLEELERRESHEEWEGFVKGWHKLEQLETEWGRVRSTFVDDTLTLNVGGSNVDVSRADLHRLPALSEVWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDALGGALPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVMLGVGDLLYRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTERKSSPGGFVFILTDGSRSFGPTKLELDPRNARRGCGVVVLGEDRMPSFHDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVWSAEVERGDDVHRFAQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCPYLVARLDQSKWTENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGEAKARVAVQATDREAIE 476
            MPNPLQKHDMFSATRRAHLEELERRESHEEWEGFVKGWHKLEQLETEWGRVRSTFVDDTLTLNVGGSNVDVSRADLHRLPALSEVWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDALGGALPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVMLGVGDLLYRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTERKSSPGGFVFILTDGSRSFGPTKLELDPRNARRGCGVVVLGEDRMPSFHDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVWSAEVERGDDVHRFAQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCPYLVARLDQSKWTENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGEAKARVAVQATDREAIE
Sbjct:    1 MPNPLQKHDMFSATRRAHLEELERRESHEEWEGFVKGWHKLEQLETEWGRVRSTFVDDTLTLNVGGSNVDVSRADLHRLPALSEVWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDALGGALPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVMLGVGDLLYRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTERKSSPGGFVFILTDGSRSFGPTKLELDPRNARRGCGVVVLGEDRMPSFHDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVWSAEVERGDDVHRFAQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCPYLVARLDQSKWTENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGEAKARVAVQATDREAIE 476          

Query:   30 EWEGFVKGWHKLEQLETEWGRVRSTFVDDTLTLNVGGSNVDVSRADLHRLPALSEVWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDALGGALPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVMLGVG---------------------DLLYRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTERKSSPGGFVFILTDGSRSFGPTKLELDPRNARRGCGVVVLGEDRMPSFHDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVWSAEVERGDDVHRF-----------------AQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCPYLVARLDQSKWTENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGEAKARVAVQATDREAIE 476
            EWE   +G  KLEQLETE G +RSTF DDTLTLNVGGSNVD+SRADL RLPALSE WKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDALGG LPTDEQAYLPYVSNALGVPSP RVPRRRVDSEGS MLG+G                     DLLYRASRDGWDT+HFH RCGDDSPMTVTLYRLNDASNRKGL CSVLGCFSSVP TPP DG T+ KSSPGGFVFILTDGSRSF PTKL++ P  A+RGCG+VVLGE  MPSFH DL + H +ERHRS TS TNAKYRLWTDS AFYVPEGCSFL+YDGID+AE + YRVWSAE ER DD+HRF                 AQSKLVEATEKG ASASAL AVYGPGVA N+RDPVVDFSV GSRTTTRITTL STLQLCPYLVARLDQSKWTENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRA WIGGE KA V V+ATDREA E
Sbjct:    4 EWEEVAEGRQKLEQLETESGMLRSTFEDDTLTLNVGGSNVDISRADLQRLPALSEAWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDALGGVLPTDEQAYLPYVSNALGVPSPARVPRRRVDSEGSAMLGIGGELDRLARTVLDWCPGNPERLDLLYRASRDGWDTRHFHARCGDDSPMTVTLYRLNDASNRKGLNCSVLGCFSSVPWTPPSDGYTKLKSSPGGFVFILTDGSRSFRPTKLKVHPHYAKRGCGLVVLGEGSMPSFHVDLEVFHGKERHRSCTSGTNAKYRLWTDSGAFYVPEGCSFLKYDGIDVAEIEVYRVWSAEEERSDDIHRFGGSIAASFEEEHKALHKAQSKLVEATEKGAASASALAAVYGPGVASNSRDPVVDFSVRGSRTTTRITTLRSTLQLCPYLVARLDQSKWTENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAGWIGGEVKAHVVVKATDREAFE 488          

Query:   24 RRESHEEWEGFVKGWHKLEQLETEWGRVR-STFVDDTLTLNVGGSNVDVSRADLHRLPALSEVWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDAL-------------GGALPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVM----LGVGDL-----------------LYRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTERKSSPGGFVFILTD----GSRSFGPTKLELDPRNARRGCGVVVLGEDRMPSF-HDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVWSA-----------EVERGDDVH-------------------------------------RFAQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLC--PYLVARLDQSKWT---ENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGEAK-ARVAVQATDREAIE 476
            R+E  + WE   +GWH+L Q   + G  + S      L LNVGGS+++  R  L      S  W L NLF+S WD+RLPRD++G +VLDESP C KHL+ +L             G  L  DE  YLPYV+ ALG+ +   +PR+ ++  G         VG+L                 LYRASRDGW    FH  CG++SP T+TL R+       G   S++G FSSVP +P   G     SS G F+F+L D    G  SF P K     R+   GC VVV G  R P F   DL +            +      L     ++ VP G +F   +G  + E + ++V+SA           +++  +D H                                       A+++L +A  K  AS  AL AVYGP VA    D VV+ SV G    TR+TTL STLQ C    L A  ++ KW    ++ D+ GR LI +CSPAVF KVLDVLRM+KRA W   + + A V V A DR A +
Sbjct:    9 RKEMSQAWEDVDRGWHELNQCRIDAGITKPSGSQQGMLRLNVGGSHLNFRRCILAGRKEPSATWALGNLFESVWDDRLPRDSDGRIVLDESPACVKHLIHSLIESSGAAPGSLPRGDTLALDEMVYLPYVARALGLSA--YIPRQGMEVVGGTTSLSHCEVGELTATLQGWCPGNPNTMRLLYRASRDGWSPYPFHASCGNNSPNTITLLRV-------GASQSIVGGFSSVPWSPHAYGGDSIMSSLGAFIFMLKDSDMGGPNSFQPVKW--GKRDNNGGCDVVV-GASRGPYFGRTDLVV----------NFNNYFPVTLQAQPYSYDVPSGSTFPNLNGQTITEIEVFQVYSAAATTSSPSKRLKIQGPEDTHGAVSTSSTNTASREANSDAETFGNAIAGALMEERIALHQAEAELEQAHSKAAASGDALAAVYGPEVARGAIDTVVELSVRG----TRMTTLRSTLQACRESALAALFNEDKWPPTDKDVDEQGRRLI-NCSPAVFQKVLDVLRMRKRAAWAASDRELAHVRVDAADRPAFD 528          

Query:   30 EWEGFVKGWHKLEQLETEWGRVRSTFVDDTLT-LNVGGSNVDVSRADLHRL-PALSEVWKLANLFDSD-WDERLPRDANGLMVLDESPVCFKHLV-DALG-----GALPTDEQAYLPYVSNALG------VPS-PTRVPRRRVDSEGSVMLGVG-------DLLYRASRDGWDTKHFHTRCGDDSPMTVTLYRLN--DASNRKGLGCSVLGCFSSVPGT--PPRDGSTERKSSPGGFVFILTDG---SRSFGPTKLELDPRNARRGCGV------VVLGEDRMPSFHDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRV----------------------------WSAEVERGDDVHRF-----------------AQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCPY--LVARLDQSKWT---ENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGEAKARVAV 467
            EW+    GW  LE    E G    + +  ++  LNVGG +V+++R+ L +   + S  W L +LF+   WD+RLPR  +G +VLDESPVC + L+ DA          P DE+ Y+  V++ALG      VP   T +P    +   + +LG         +LLYRASRDGW     H RCGDDSP T++L+R+   DA+       S++G FSSVP T  PP +   +       F+FIL DG   S +F P    L  RN +           ++ G  R+     DL ++         T+ T     L   +  + VP G  F+   G  +A+ + +RV                             SAE E  +DV+RF                 AQ +LV+A     AS  AL AVYGP  A   +DP+V+ SV GSRTT R+TTL STLQ CP   L AR D++KW    ++KD HGR ++KDCSP+VFSKVLDVLRMKKR  W G + K   AV
Sbjct:    4 EWDKLDSGWEALESKMNETGMSMVSSIQPSIVRLNVGGLDVNIARSVLRKAGESSSSTWTLGDLFEGCVWDKRLPRCEDGRIVLDESPVCVEELLCDASSKRPGNSNFPDDEKPYIGGVASALGLDLGMTVPGGSTTLPHDEAERLTATILGWCPGRPEGLELLYRASRDGWSGDALHARCGDDSPSTISLFRVKTQDANTSD----SIVGGFSSVPWTALPPENRGLDS------FLFILKDGIEESHNFQPAIWGLRIRNPKPSGAYDMEKFGLIFGRGRI----FDLSVVW--------TNQT-----LVAGNQVYAVPPGFQFIRLGGRAIADVEVFRVRQTMGTLPTTPPTVTGLIDCAAYFEASAMSAE-EHENDVYRFGTSIAGSLKDERAALHTAQRELVQANTMAAASLKALAAVYGPHTAAGVKDPIVELSVRGSRTTERMTTLLSTLQACPESALAARFDEAKWPVTEKDKDAHGRRVMKDCSPSVFSKVLDVLRMKKREAWAGDDGKMGAAV 499          

Query:    9 DMFSATRRAHLEELE------RRESHEEWEGFVKGWHKLEQLETEWGRVRSTFVDD-TLTLNVGGSNVDVSRADLHRLPALSEVWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDAL-------------GGALPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVML----GVGDL-----------------LYRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTERKSSPGGFVFILTD----GSRSFGPTKLELDPRNARRGCGVVVLGEDRMPSF-HDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVWSAEVERGDDVHRF-----AQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLC--PYLVARLDQSKWT---ENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGEAK-ARVAVQATDREAIE 476
            D FSAT  A+ +E+E      R+   + WE   +GWH+L Q   + G  +     +  L LNVGGS++   R  L      S  W L NLF+S WD+RLPRD++G +VLD+SP C K L+ +L             G  L  DE AYLP+V+ ALG+ +   +P + ++  G   +     VG+L                 LYRASRD W    FH  CG++SP T+TL R+       G   S++G FSSVP +P   G     SS G F+F+L D    G  SF P K      N   G   VV+G  R P F   DL +           + T     L     ++ VP   +F   +G  + E + ++V       G  +        A+++L  A  K   S  AL AVYGP VA    D VV+ SV G    TR+TTL STL+ C    L A  ++ KW    ++ D+ GR LI +CSPAVF KVLDVLRM+KRA W   + + A V V A DR A +
Sbjct:   10 DTFSATVTAYSKEMEAALGQRRKGMSQAWEDVERGWHELNQCRIDAGITKPFGSQEGMLRLNVGGSHLRFRRCVLDGKKEPSATWALGNLFESVWDDRLPRDSDGRIVLDKSPACVKDLIHSLIESSGAAPGSLPRGETLAPDEMAYLPHVARALGLSA--YIPLQGMEVVGGTTILSHCEVGELTATLQGWCPGNPNTMQLLYRASRDDWSPYPFHASCGNNSPNTITLLRV-------GASASIVGGFSSVPWSPHAYGGDSVMSSLGAFIFMLKDSDMGGPNSFQPVKWSKRDNN---GGYDVVVGASRGPFFGRTDLVV-----------NFTYVPVTLQAQPYSYDVPSVPAFPNLNGQTITEIEVFQVNICNAIAGALMEERIALYQAEAELEHAHSKAAVSGRALAAVYGPEVARGAIDTVVELSVRG----TRMTTLRSTLRACRESALAALFNEDKWPATDKDVDEQGRRLI-NCSPAVFQKVLDVLRMRKRAAWAASDRESAHVRVDAADRPAFD 506          

Query:    8 HDMFSATRRAHLEELER------RESHEEWEGFVKGWHKLEQLETEWGRVR-STFVDDTLTLNVGGSNVDVSRADLH-RLPALSEVWKLANLFDSD-WDERLPRDANGLMVLDESPVCFKHLVDALGGA-------LPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVMLGVGDLLYRASRDGWDTKHFHTRCGDDSPMTVTLY--RLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTERKSSPGGFVFILTDGSRSFGPTKLELDPRNARRG-CGVVVLGEDRMPSFHDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFY-VPEGCSFLEYDGIDMAETKGYRV---------------------WSAEVERGDDVHRF-----------------AQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCPY--LVARLDQSKWT---ENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGEAKAR----VAVQATDREAIE 476
            H+ F    + H +ELE       +E+ +EW+    GW  LE    E G    S+F    + L+VGG +V+++ + L  ++ A S  W L +LF    WD+RLP   +G +VLDESPVC + ++     +       LP DE+ Y+ YV++ALG+     +   + D              RASRD W    FH RCGDDSP T++L+      A+N      SV+G FS VP T   + S    S PG F+F+L DG+   G   ++      + G  G VV G    P   D +  LH                R++T     Y +P    FL + G ++ + + +RV                      SAE E  +DV+RF                 AQ +LV+A     AS  AL AVYGP +A    D VV+ SV G R T R+TTL STLQ CP   L AR D++KW    + KD HGR +IKDCSP VF+KVLDVLRMKKR  W   + K R    VA++A DR   E
Sbjct:    9 HECFLTATKTHAQELEELLEDRAKETKKEWDKLDSGWEALEFKMNETGMSTVSSFHPSIVRLDVGGLDVNIAWSVLREKVVASSSSWTLGDLFKGGVWDKRLPSPEDGRIVLDESPVCVEEILSDGASSKRSGSNNLPDDEKPYIGYVASALGLGLQPGMVSWQAD--------------RASRDSWSDHAFHARCGDDSPSTISLFCVEAQGANNSD----SVVGRFSVVPWTASPEFSPVLPS-PGSFLFMLKDGNE--GSDAVQPSKWGPKVGYTGQVVDGRTEGPV--DWVMCLH----------------RMFTVHCGIYDIPTEHPFLYHMGREVVDIEVFRVLPTSLTVTGLIDCAAYFKCSDMSAE-EHENDVYRFGMSIAGSLRDERAALHTAQRELVKANTIAAASVEALAAVYGPNIAAGVEDRVVELSVRGPRKTERMTTLLSTLQACPESALAARFDEAKWPVTDKEKDAHGRRVIKDCSPLVFAKVLDVLRMKKREAWADDDKKVRAAVLVAIKAADRAPFE 504          

Query:   24 RRESHEEWEGFVKGWHKLEQLETEWGRVRSTFVDDTLT-LNVGGSNVDVSRADLHRLPALSE-VWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDAL--------------GGALPTDEQAYLPYVSNALG-----------VPSPTRVPRRRVDSEGSVML--------GVGDLLYRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTER---KSSPGGFVFILTD---GSRSFGPTKLE----LDPRNARRGCGVVVLGEDRMPSFHDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVWS-----------------------AEVERGDDVHRFAQS-----------------KLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCP--YLVARLDQSKWTENK---DKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGE-----AKARVAVQATDREAIE 476
            R E   EW+   +GW  L +  TE G  +     + +  LNVGG  +   R+ L          W L NLF+++WD+R+PRD++G +VLDESP C K LV  L              G     ++ A L Y +  LG           +   T +      S+ + ++        G  +LLYRASRDGW+   F+ RC  DSP TVTL R+       G   S++G FSSVP +P     +     + SPG FVFIL D   GS +F P K      L  +   +GCG      D   +++ ++  +                    TD+  + VP G  FL+ +G  + + + +RV S                       A V   DDV  F Q                  +L  A  +  A A+AL AVYGP VA   ++ VV+ SV G    T +TTL STL++CP   L AR D+ KW   K   D  GR +I DC PAVFSKVLDVLR+ KRA W GGE      + RV ++  DR A E
Sbjct:   31 RLEMDHEWDSIDEGWQTLRERMTEVGITKPLESKEGIVKLNVGGLLLAFRRSVLDSEGKQQPPTWALGNLFEAEWDKRVPRDSDGHIVLDESPTCVKQLVHRLLTASSSSKATVGRAGDFARNEDPALLHYTAGVLGLSGCLAPVGMSIQGGTTIFEPHETSKLTAVVQDWCPGHPGGLELLYRASRDGWNGATFNARCKGDSPSTVTLLRVKGCET--GGTDSIIGGFSSVPWSPAIQNYSYGYYLRGSPGAFVFILKDEGKGSSTFPPMKWGVKNGLAAKAVNQGCGPCFGECDLKVNWNGNMSTVG-------------------TDNSTYDVPAGSHFLQLNGRHLLDIEAFRVCSKPTHTLPLAKQEHRAGEGTNTPTAPVRTSDDVPTFGQLIADSLMEAEMVLQDAGIELALAKARTTACATALAAVYGPDVASGQQEDVVELSVRG----TAMTTLRSTLRVCPDSALAARFDEGKWPAAKKDLDSDGRRMI-DCRPAVFSKVLDVLRIAKRAAWAGGENLQGMKETRVTIKPGDRVAFE 552          

Query:   83 SEVWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDALGGALPTDEQAYLPYVSN--ALGVPSPTRVPRRRVDSEGSVMLGVGDLLYRAS---RDGWDTKHFHT----------------------RCGDDS-PMTVTLYRLNDASNRKGLGCS----VLGCFSSVPGTPPRDGSTER--KSSPGGFVFILTDGS-RSFGPTKLELDPRNARRGCGVVVLGEDRMPSFHD--DLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVW-----------------------SAEVERGDDVHRF-----------------AQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCP--YLVARLDQSKWT---ENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGE----------AKARVAVQATDREAIE 476
            S  W L +LF+++WD+R+PRDA+G +VLDESP+C KHL++AL            P  +N  A G    +R  +  +    + +LG+   L       + G  T   H                       RCGD S P T+T  R+      KG G +    ++G FSS+P       S       SPG F+F+L DG  R  G  +         R    V  G+   P F +  DL ++          + T +  R  T +  ++ P G  F E +G  + + + +RV                         A V+  DDV  F                 A ++L  A  +  A A+A+ AVYGP VA    D VV+ +V G    TR+TTL STL++CP   L A  ++ +W    ++ D +GR +I DC P+VFSKVLDVLR+ KRA W   E           K RV ++A D  A E
Sbjct:   46 SSTWALGDLFEAEWDKRVPRDADGRIVLDESPICVKHLIEAL---------LLRPNAANGTATGEADMSRDDQPDLFHHTARVLGLSGQLAPVGMTIKGGTTTFDPHEASKLTAVVQRWCPGNPGAACQDRCGDQSSPTTITFLRV------KGRGAAATDCIIGGFSSIPWDDFMYDSDAGYYSPSPGAFLFMLKDGEGRHSGVYQSTKWGVKDGRSAYAVYRGQGYGPCFGEGRDLHVVW---------NGTESAVR--TGNQTYHAPTGSPFPELNGCRLVDVETFRVGPKPNTPTSSTKQEDHAVEDKTGPGAPVKTADDVRSFGDLVADSLMEEEKLLQEAANELSLAKARTMACATAVAAVYGPEVATGTEDDVVELNVRG----TRMTTLRSTLRICPDSALAAWFNEEQWPVAEKDLDSNGRRII-DCKPSVFSKVLDVLRIAKRAAWARSEEGPVRNEKRRVKPRVTIKAGDCAAFE 500          

Query:   29 EEWEGFVKGWHKLEQLETEWGRVRSTFVDDTLTLNVGGSNVDVSRADLHRLPALSEVWK---LANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDAL--GG----------------------ALPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVMLG---------------------VGD-----LLYRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDG-STERKSSPGGFVFILTDGSRSFGPTKLELDPRNARRGCGV-------VVLGEDRMPSFH-DDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRV-WSAEVER-----------------------------GDDVHR----------------------FAQSKLVEATEKGEASASALGAVYGPGVALNN--RDPVVDFSVCGSRTTTRITTLHSTLQLCPYLVARLDQSKWTENKDKH---------------GRWLIK-----DCSPAVFSKVLDVLRMKKRAEWI------------GGEAKARVAVQATDR 472
            E W     GW + +Q   + G   +T  +  L LN+GG   +V R+    L A +E +K   L  LF+  WDER+PRD +G +VLDESP C KH++  L  GG                      A+   E+ YL Y+S+ LG+   + V     +++G V+ G                      GD     LLYRASRDG+ T  F  +C      T+TL R+     R     SV+G FS +   P   G  T  + S   F+F+L      F PT  +   +     C +       V  G    P+F  +D+ +   E   +S +S       L T  + + V E   F+  DG ++AE + +RV  +A VE                               D++                        +AQ++L EA ++  A+A AL  VYGPGVA      + VV+ SV G      +TTL STL+ CP        S W    D+                GR         DC P+ FSK+LDV+RM+KRA W+            GG    R+ V  +DR
Sbjct:   36 EPWRDLENGWERHQQYLVDVGVRPTTGNEGVLRLNIGGVPANVHRS----LIAEAEGFKGSVLGALFEQMWDERVPRDMDGRIVLDESPACVKHIIHTLLRGGCTTRTKETASLCHFRSAAGPSAAVAAHEEPYLLYISHVLGL---SNVIPACPNTKGMVVAGGTTTANPLQLPQWSSLLRSWCPGDPAGLHLLYRASRDGFSTGPFQ-QCVRGVCETITLIRVKSDDGRPD---SVVGGFSDIEIVPQEVGMETGNQRSSSAFLFLLDSPGGGF-PTAKKWSIKEGEDSCAIHWPETADVCAG----PAFGLEDMCVTFSESEGQSGSSGCT----LSTGGEFYDVDEDSPFVGLDGKEVAEIEIFRVDKTARVEHQDVAPVATTPPQSNIFPDKRKHFLHPDRSADEIEAAYALQFGSSLAELLMEEQMALAYAQTELEEAKKRAAATARALAIVYGPGVASARVEENAVVELSVRGMS----VTTLRSTLEACPDSAF----STWLGAADRPVGCGDDGEANDEGLGGRTSEDCRRKVDCDPSCFSKILDVMRMRKRAAWVTDDQQGALIREAGGGHTVRIPVPESDR 599          

Query:   62 LNVGGSNVDVSRADLHRL------PALSEVWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDAL---GGALPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVMLGVGDLL--------------YRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTERKSSPGGFVFIL----TDGSRSFGPTKLELDPRNARRGCGVVVLGEDRMPSFHDDLGI-LHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVW----------------------------------SAEVERGDDVH-----------------RFAQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCP--YLVARLD 417
            LN     +D  R DL           +S  W L +LF+S WD+R+PRDANGL+VLDESP+C KHL+ AL    GA   D     P+  +  G    TR P        S +  + D+L              YRASRDGW  + FH  CG DSP+T+TL+R+  ++    +  +++G FS    +   +     + SP  F+ ++     DGS SF P+K        RRG    +      P F  DL + LH++          NA++ L     AF V E  +F    G  + E + +RV                                   +A     DDV                  R A ++L +   K   S +AL AVYGP VA    D VV+ SV      TR+TTL STLQ CP   L AR D
Sbjct:   35 LNAAWDGIDKHRGDLEARMVEVDGDGISPTWNLCDLFESMWDKRIPRDANGLIVLDESPICVKHLLRALLKKSGAAALDS----PFGCSGQGWLR-TRWPTSPRSWRLSEVCPLTDILQGWCPGNPSRLHLIYRASRDGWGGEAFHECCGKDSPVTITLFRVLSSAGTA-VTDTIVGGFSRSSWS---NSCPFSRFSPDAFICMVKYGSADGSSSFQPSKWI-----PRRGLPNYLGTSSHGPCFGSDLCMSLHDD----------NARF-LHVAIGAFNVSEDSAFFTLGGQTVKEIEVFRVCREATAGSPPPPPRAKPATTSENGLIDLTSGGPSDAATESYDDDVRMSGALIAESLMEERAALREAFAELAQPNTKAGESVNALTAVYGPDVAAGKEDTVVELSV----RETRLTTLRSTLQACPDSALAARFD 442          

Query:    1 MPNPLQKHDMFSATRRAHLEELERRESHEEWEGFVKGWHKLEQLETEWGRVRSTFVDDTLTLNVGGSNVDVSRADLHRLPALSEVWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDALGGALPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVMLGVGDLLYRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTERKSSPGGFVFILTDGSRSFGPTKLELDPRNARRGCGVVVLGEDRMPSFHDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVWSAEVERGDDVHRFAQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCPYLVARLDQSKWTENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGEAKARVAVQATDREAIE 1428
            MPNPLQKHDMFSATRRAHLEELERRESHEEWEGFVKGWHKLEQLETEWGRVRSTFVDDTLTLNVGGSNVDVSRADLHRLPALSEVWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDALGGALPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVMLGVGDLLYRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTERKSSPGGFVFILTDGSRSFGPTKLELDPRNARRGCGVVVLGEDRMPSFHDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVWSAEVERGDDVHRFAQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCPYLVARLDQSKWTENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGEAKARVAVQATDREAIE
Sbjct:    1 MPNPLQKHDMFSATRRAHLEELERRESHEEWEGFVKGWHKLEQLETEWGRVRSTFVDDTLTLNVGGSNVDVSRADLHRLPALSEVWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDALGGALPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVMLGVGDLLYRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTERKSSPGGFVFILTDGSRSFGPTKLELDPRNARRGCGVVVLGEDRMPSFHDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVWSAEVERGDDVHRFAQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCPYLVARLDQSKWTENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGEAKARVAVQATDREAIE 476          

Query:   88 EWEGFVKGWHKLEQLETEWGRVRSTFVDDTLTLNVGGSNVDVSRADLHRLPALSEVWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDALGGALPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVMLGVG---------------------DLLYRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTERKSSPGGFVFILTDGSRSFGPTKLELDPRNARRGCGVVVLGEDRMPSFHDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVWSAEVERGDDVHRF-----------------AQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCPYLVARLDQSKWTENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGEAKARVAVQATDREAIE 1428
            EWE   +G  KLEQLETE G +RSTF DDTLTLNVGGSNVD+SRADL RLPALSE WKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDALGG LPTDEQAYLPYVSNALGVPSP RVPRRRVDSEGS MLG+G                     DLLYRASRDGWDT+HFH RCGDDSPMTVTLYRLNDASNRKGL CSVLGCFSSVP TPP DG T+ KSSPGGFVFILTDGSRSF PTKL++ P  A+RGCG+VVLGE  MPSFH DL + H +ERHRS TS TNAKYRLWTDS AFYVPEGCSFL+YDGID+AE + YRVWSAE ER DD+HRF                 AQSKLVEATEKG ASASAL AVYGPGVA N+RDPVVDFSV GSRTTTRITTL STLQLCPYLVARLDQSKWTENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRA WIGGE KA V V+ATDREA E
Sbjct:    4 EWEEVAEGRQKLEQLETESGMLRSTFEDDTLTLNVGGSNVDISRADLQRLPALSEAWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDALGGVLPTDEQAYLPYVSNALGVPSPARVPRRRVDSEGSAMLGIGGELDRLARTVLDWCPGNPERLDLLYRASRDGWDTRHFHARCGDDSPMTVTLYRLNDASNRKGLNCSVLGCFSSVPWTPPSDGYTKLKSSPGGFVFILTDGSRSFRPTKLKVHPHYAKRGCGLVVLGEGSMPSFHVDLEVFHGKERHRSCTSGTNAKYRLWTDSGAFYVPEGCSFLKYDGIDVAEIEVYRVWSAEEERSDDIHRFGGSIAASFEEEHKALHKAQSKLVEATEKGAASASALAAVYGPGVASNSRDPVVDFSVRGSRTTTRITTLRSTLQLCPYLVARLDQSKWTENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAGWIGGEVKAHVVVKATDREAFE 488          

Query:   70 RRESHEEWEGFVKGWHKLEQLETEWGRVR-STFVDDTLTLNVGGSNVDVSRADLHRLPALSEVWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDAL-------------GGALPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVM----LGVGDL-----------------LYRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTERKSSPGGFVFILTD----GSRSFGPTKLELDPRNARRGCGVVVLGEDRMPSF-HDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVWSA-----------EVERGDDVH-------------------------------------RFAQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLC--PYLVARLDQSKWT---ENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGEAK-ARVAVQATDREAIE 1428
            R+E  + WE   +GWH+L Q   + G  + S      L LNVGGS+++  R  L      S  W L NLF+S WD+RLPRD++G +VLDESP C KHL+ +L             G  L  DE  YLPYV+ ALG+ +   +PR+ ++  G         VG+L                 LYRASRDGW    FH  CG++SP T+TL R+       G   S++G FSSVP +P   G     SS G F+F+L D    G  SF P K     R+   GC VVV G  R P F   DL +            +      L     ++ VP G +F   +G  + E + ++V+SA           +++  +D H                                       A+++L +A  K  AS  AL AVYGP VA    D VV+ SV G    TR+TTL STLQ C    L A  ++ KW    ++ D+ GR LI +CSPAVF KVLDVLRM+KRA W   + + A V V A DR A +
Sbjct:    9 RKEMSQAWEDVDRGWHELNQCRIDAGITKPSGSQQGMLRLNVGGSHLNFRRCILAGRKEPSATWALGNLFESVWDDRLPRDSDGRIVLDESPACVKHLIHSLIESSGAAPGSLPRGDTLALDEMVYLPYVARALGLSA--YIPRQGMEVVGGTTSLSHCEVGELTATLQGWCPGNPNTMRLLYRASRDGWSPYPFHASCGNNSPNTITLLRV-------GASQSIVGGFSSVPWSPHAYGGDSIMSSLGAFIFMLKDSDMGGPNSFQPVKW--GKRDNNGGCDVVV-GASRGPYFGRTDLVV----------NFNNYFPVTLQAQPYSYDVPSGSTFPNLNGQTITEIEVFQVYSAAATTSSPSKRLKIQGPEDTHGAVSTSSTNTASREANSDAETFGNAIAGALMEERIALHQAEAELEQAHSKAAASGDALAAVYGPEVARGAIDTVVELSVRG----TRMTTLRSTLQACRESALAALFNEDKWPPTDKDVDEQGRRLI-NCSPAVFQKVLDVLRMRKRAAWAASDRELAHVRVDAADRPAFD 528          

Query:   88 EWEGFVKGWHKLEQLETEWGRVRSTFVDDTLT-LNVGGSNVDVSRADLHRL-PALSEVWKLANLFDSD-WDERLPRDANGLMVLDESPVCFKHLV-DALG-----GALPTDEQAYLPYVSNALG------VPS-PTRVPRRRVDSEGSVMLGVG-------DLLYRASRDGWDTKHFHTRCGDDSPMTVTLYRLN--DASNRKGLGCSVLGCFSSVPGT--PPRDGSTERKSSPGGFVFILTDG---SRSFGPTKLELDPRNARRGCGV------VVLGEDRMPSFHDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRV----------------------------WSAEVERGDDVHRF-----------------AQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCPY--LVARLDQSKWT---ENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGEAKARVAVQATDREA 1422
            EW+    GW  LE    E G    + +  ++  LNVGG +V+++R+ L +   + S  W L +LF+   WD+RLPR  +G +VLDESPVC + L+ DA          P DE+ Y+  V++ALG      VP   T +P    +   + +LG         +LLYRASRDGW     H RCGDDSP T++L+R+   DA+       S++G FSSVP T  PP +   +       F+FIL DG   S +F P    L  RN +           ++ G  R+     DL ++         T+ T     L   +  + VP G  F+   G  +A+ + +RV                             SAE E  +DV+RF                 AQ +LV+A     AS  AL AVYGP  A   +DP+V+ SV GSRTT R+TTL STLQ CP   L AR D++KW    ++KD HGR ++KDCSP+VFSKVLDVLRMKKR  W G + K   AV    ++A
Sbjct:    4 EWDKLDSGWEALESKMNETGMSMVSSIQPSIVRLNVGGLDVNIARSVLRKAGESSSSTWTLGDLFEGCVWDKRLPRCEDGRIVLDESPVCVEELLCDASSKRPGNSNFPDDEKPYIGGVASALGLDLGMTVPGGSTTLPHDEAERLTATILGWCPGRPEGLELLYRASRDGWSGDALHARCGDDSPSTISLFRVKTQDANTSD----SIVGGFSSVPWTALPPENRGLDS------FLFILKDGIEESHNFQPAIWGLRIRNPKPSGAYDMEKFGLIFGRGRI----FDLSVVW--------TNQT-----LVAGNQVYAVPPGFQFIRLGGRAIADVEVFRVRQTMGTLPTTPPTVTGLIDCAAYFEASAMSAE-EHENDVYRFGTSIAGSLKDERAALHTAQRELVQANTMAAASLKALAAVYGPHTAAGVKDPIVELSVRGSRTTERMTTLLSTLQACPESALAARFDEAKWPVTEKDKDAHGRRVMKDCSPSVFSKVLDVLRMKKREAWAGDDGKMGAAVLVAIKDA 506          

Query:   25 DMFSATRRAHLEELE------RRESHEEWEGFVKGWHKLEQLETEWGRVRSTFVDD-TLTLNVGGSNVDVSRADLHRLPALSEVWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDAL-------------GGALPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVML----GVGDL-----------------LYRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTERKSSPGGFVFILTD----GSRSFGPTKLELDPRNARRGCGVVVLGEDRMPSF-HDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVWSAEVERGDDVHRF-----AQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLC--PYLVARLDQSKWT---ENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGEAK-ARVAVQATDREAIE 1428
            D FSAT  A+ +E+E      R+   + WE   +GWH+L Q   + G  +     +  L LNVGGS++   R  L      S  W L NLF+S WD+RLPRD++G +VLD+SP C K L+ +L             G  L  DE AYLP+V+ ALG+ +   +P + ++  G   +     VG+L                 LYRASRD W    FH  CG++SP T+TL R+       G   S++G FSSVP +P   G     SS G F+F+L D    G  SF P K      N   G   VV+G  R P F   DL +           + T     L     ++ VP   +F   +G  + E + ++V       G  +        A+++L  A  K   S  AL AVYGP VA    D VV+ SV G    TR+TTL STL+ C    L A  ++ KW    ++ D+ GR LI +CSPAVF KVLDVLRM+KRA W   + + A V V A DR A +
Sbjct:   10 DTFSATVTAYSKEMEAALGQRRKGMSQAWEDVERGWHELNQCRIDAGITKPFGSQEGMLRLNVGGSHLRFRRCVLDGKKEPSATWALGNLFESVWDDRLPRDSDGRIVLDKSPACVKDLIHSLIESSGAAPGSLPRGETLAPDEMAYLPHVARALGLSA--YIPLQGMEVVGGTTILSHCEVGELTATLQGWCPGNPNTMQLLYRASRDDWSPYPFHASCGNNSPNTITLLRV-------GASASIVGGFSSVPWSPHAYGGDSVMSSLGAFIFMLKDSDMGGPNSFQPVKWSKRDNN---GGYDVVVGASRGPFFGRTDLVV-----------NFTYVPVTLQAQPYSYDVPSVPAFPNLNGQTITEIEVFQVNICNAIAGALMEERIALYQAEAELEHAHSKAAVSGRALAAVYGPEVARGAIDTVVELSVRG----TRMTTLRSTLRACRESALAALFNEDKWPATDKDVDEQGRRLI-NCSPAVFQKVLDVLRMRKRAAWAASDRESAHVRVDAADRPAFD 506          

Query:   22 HDMFSATRRAHLEELER------RESHEEWEGFVKGWHKLEQLETEWGRVR-STFVDDTLTLNVGGSNVDVSRADLH-RLPALSEVWKLANLFDSD-WDERLPRDANGLMVLDESPVCFKHLVDALGGA-------LPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVMLGVGDLLYRASRDGWDTKHFHTRCGDDSPMTVTLY--RLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTERKSSPGGFVFILTDGSRSFGPTKLELDPRNARRG-CGVVVLGEDRMPSFHDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFY-VPEGCSFLEYDGIDMAETKGYRV---------------------WSAEVERGDDVHRF-----------------AQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCPY--LVARLDQSKWT---ENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGEAKAR----VAVQATDREAIE 1428
            H+ F    + H +ELE       +E+ +EW+    GW  LE    E G    S+F    + L+VGG +V+++ + L  ++ A S  W L +LF    WD+RLP   +G +VLDESPVC + ++     +       LP DE+ Y+ YV++ALG+     +   + D              RASRD W    FH RCGDDSP T++L+      A+N      SV+G FS VP T   + S    S PG F+F+L DG+   G   ++      + G  G VV G    P   D +  LH                R++T     Y +P    FL + G ++ + + +RV                      SAE E  +DV+RF                 AQ +LV+A     AS  AL AVYGP +A    D VV+ SV G R T R+TTL STLQ CP   L AR D++KW    + KD HGR +IKDCSP VF+KVLDVLRMKKR  W   + K R    VA++A DR   E
Sbjct:    9 HECFLTATKTHAQELEELLEDRAKETKKEWDKLDSGWEALEFKMNETGMSTVSSFHPSIVRLDVGGLDVNIAWSVLREKVVASSSSWTLGDLFKGGVWDKRLPSPEDGRIVLDESPVCVEEILSDGASSKRSGSNNLPDDEKPYIGYVASALGLGLQPGMVSWQAD--------------RASRDSWSDHAFHARCGDDSPSTISLFCVEAQGANNSD----SVVGRFSVVPWTASPEFSPVLPS-PGSFLFMLKDGNE--GSDAVQPSKWGPKVGYTGQVVDGRTEGPV--DWVMCLH----------------RMFTVHCGIYDIPTEHPFLYHMGREVVDIEVFRVLPTSLTVTGLIDCAAYFKCSDMSAE-EHENDVYRFGMSIAGSLRDERAALHTAQRELVKANTIAAASVEALAAVYGPNIAAGVEDRVVELSVRGPRKTERMTTLLSTLQACPESALAARFDEAKWPVTDKEKDAHGRRVIKDCSPLVFAKVLDVLRMKKREAWADDDKKVRAAVLVAIKAADRAPFE 504          

Query:   70 RRESHEEWEGFVKGWHKLEQLETEWGRVRSTFVDDTLT-LNVGGSNVDVSRADLHRLPALSE-VWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDAL--------------GGALPTDEQAYLPYVSNALG-----------VPSPTRVPRRRVDSEGSVML--------GVGDLLYRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTER---KSSPGGFVFILTD---GSRSFGPTKLE----LDPRNARRGCGVVVLGEDRMPSFHDDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVWS-----------------------AEVERGDDVHRFAQS-----------------KLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCP--YLVARLDQSKWTENK---DKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGE-----AKARVAVQATDREAIE 1428
            R E   EW+   +GW  L +  TE G  +     + +  LNVGG  +   R+ L          W L NLF+++WD+R+PRD++G +VLDESP C K LV  L              G     ++ A L Y +  LG           +   T +      S+ + ++        G  +LLYRASRDGW+   F+ RC  DSP TVTL R+       G   S++G FSSVP +P     +     + SPG FVFIL D   GS +F P K      L  +   +GCG      D   +++ ++  +                    TD+  + VP G  FL+ +G  + + + +RV S                       A V   DDV  F Q                  +L  A  +  A A+AL AVYGP VA   ++ VV+ SV G    T +TTL STL++CP   L AR D+ KW   K   D  GR +I DC PAVFSKVLDVLR+ KRA W GGE      + RV ++  DR A E
Sbjct:   31 RLEMDHEWDSIDEGWQTLRERMTEVGITKPLESKEGIVKLNVGGLLLAFRRSVLDSEGKQQPPTWALGNLFEAEWDKRVPRDSDGHIVLDESPTCVKQLVHRLLTASSSSKATVGRAGDFARNEDPALLHYTAGVLGLSGCLAPVGMSIQGGTTIFEPHETSKLTAVVQDWCPGHPGGLELLYRASRDGWNGATFNARCKGDSPSTVTLLRVKGCET--GGTDSIIGGFSSVPWSPAIQNYSYGYYLRGSPGAFVFILKDEGKGSSTFPPMKWGVKNGLAAKAVNQGCGPCFGECDLKVNWNGNMSTVG-------------------TDNSTYDVPAGSHFLQLNGRHLLDIEAFRVCSKPTHTLPLAKQEHRAGEGTNTPTAPVRTSDDVPTFGQLIADSLMEAEMVLQDAGIELALAKARTTACATALAAVYGPDVASGQQEDVVELSVRG----TAMTTLRSTLRVCPDSALAARFDEGKWPAAKKDLDSDGRRMI-DCRPAVFSKVLDVLRIAKRAAWAGGENLQGMKETRVTIKPGDRVAFE 552          

Query:  247 SEVWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDALGGALPTDEQAYLPYVSN--ALGVPSPTRVPRRRVDSEGSVMLGVGDLLYRAS---RDGWDTKHFHT----------------------RCGDDS-PMTVTLYRLNDASNRKGLGCS----VLGCFSSVPGTPPRDGSTER--KSSPGGFVFILTDGS-RSFGPTKLELDPRNARRGCGVVVLGEDRMPSFHD--DLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVW-----------------------SAEVERGDDVHRF-----------------AQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCP--YLVARLDQSKWT---ENKDKHGRWLIKDCSPAVFSKVLDVLRMKKRAEWIGGE----------AKARVAVQATDREAIE 1428
            S  W L +LF+++WD+R+PRDA+G +VLDESP+C KHL++AL            P  +N  A G    +R  +  +    + +LG+   L       + G  T   H                       RCGD S P T+T  R+      KG G +    ++G FSS+P       S       SPG F+F+L DG  R  G  +         R    V  G+   P F +  DL ++          + T +  R  T +  ++ P G  F E +G  + + + +RV                         A V+  DDV  F                 A ++L  A  +  A A+A+ AVYGP VA    D VV+ +V G    TR+TTL STL++CP   L A  ++ +W    ++ D +GR +I DC P+VFSKVLDVLR+ KRA W   E           K RV ++A D  A E
Sbjct:   46 SSTWALGDLFEAEWDKRVPRDADGRIVLDESPICVKHLIEAL---------LLRPNAANGTATGEADMSRDDQPDLFHHTARVLGLSGQLAPVGMTIKGGTTTFDPHEASKLTAVVQRWCPGNPGAACQDRCGDQSSPTTITFLRV------KGRGAAATDCIIGGFSSIPWDDFMYDSDAGYYSPSPGAFLFMLKDGEGRHSGVYQSTKWGVKDGRSAYAVYRGQGYGPCFGEGRDLHVVW---------NGTESAVR--TGNQTYHAPTGSPFPELNGCRLVDVETFRVGPKPNTPTSSTKQEDHAVEDKTGPGAPVKTADDVRSFGDLVADSLMEEEKLLQEAANELSLAKARTMACATAVAAVYGPEVATGTEDDVVELNVRG----TRMTTLRSTLRICPDSALAAWFNEEQWPVAEKDLDSNGRRII-DCKPSVFSKVLDVLRIAKRAAWARSEEGPVRNEKRRVKPRVTIKAGDCAAFE 500          

Query:   85 EEWEGFVKGWHKLEQLETEWGRVRSTFVDDTLTLNVGGSNVDVSRADLHRLPALSEVWK---LANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDAL--GG----------------------ALPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVMLG---------------------VGD-----LLYRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDG-STERKSSPGGFVFILTDGSRSFGPTKLELDPRNARRGCGV-------VVLGEDRMPSFH-DDLGILHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRV-WSAEVER-----------------------------GDDVHR----------------------FAQSKLVEATEKGEASASALGAVYGPGVALNN--RDPVVDFSVCGSRTTTRITTLHSTLQLCPYLVARLDQSKWTENKDKH---------------GRWLIK-----DCSPAVFSKVLDVLRMKKRAEWI------------GGEAKARVAVQATDR 1416
            E W     GW + +Q   + G   +T  +  L LN+GG   +V R+    L A +E +K   L  LF+  WDER+PRD +G +VLDESP C KH++  L  GG                      A+   E+ YL Y+S+ LG+   + V     +++G V+ G                      GD     LLYRASRDG+ T  F  +C      T+TL R+     R     SV+G FS +   P   G  T  + S   F+F+L      F PT  +   +     C +       V  G    P+F  +D+ +   E   +S +S       L T  + + V E   F+  DG ++AE + +RV  +A VE                               D++                        +AQ++L EA ++  A+A AL  VYGPGVA      + VV+ SV G      +TTL STL+ CP        S W    D+                GR         DC P+ FSK+LDV+RM+KRA W+            GG    R+ V  +DR
Sbjct:   36 EPWRDLENGWERHQQYLVDVGVRPTTGNEGVLRLNIGGVPANVHRS----LIAEAEGFKGSVLGALFEQMWDERVPRDMDGRIVLDESPACVKHIIHTLLRGGCTTRTKETASLCHFRSAAGPSAAVAAHEEPYLLYISHVLGL---SNVIPACPNTKGMVVAGGTTTANPLQLPQWSSLLRSWCPGDPAGLHLLYRASRDGFSTGPFQ-QCVRGVCETITLIRVKSDDGRPD---SVVGGFSDIEIVPQEVGMETGNQRSSSAFLFLLDSPGGGF-PTAKKWSIKEGEDSCAIHWPETADVCAG----PAFGLEDMCVTFSESEGQSGSSGCT----LSTGGEFYDVDEDSPFVGLDGKEVAEIEIFRVDKTARVEHQDVAPVATTPPQSNIFPDKRKHFLHPDRSADEIEAAYALQFGSSLAELLMEEQMALAYAQTELEEAKKRAAATARALAIVYGPGVASARVEENAVVELSVRGMS----VTTLRSTLEACPDSAF----STWLGAADRPVGCGDDGEANDEGLGGRTSEDCRRKVDCDPSCFSKILDVMRMRKRAAWVTDDQQGALIREAGGGHTVRIPVPESDR 599          

Query:  184 LNVGGSNVDVSRADLHRL------PALSEVWKLANLFDSDWDERLPRDANGLMVLDESPVCFKHLVDAL---GGALPTDEQAYLPYVSNALGVPSPTRVPRRRVDSEGSVMLGVGDLL--------------YRASRDGWDTKHFHTRCGDDSPMTVTLYRLNDASNRKGLGCSVLGCFSSVPGTPPRDGSTERKSSPGGFVFIL----TDGSRSFGPTKLELDPRNARRGCGVVVLGEDRMPSFHDDLGI-LHEEERHRSRTSSTNAKYRLWTDSDAFYVPEGCSFLEYDGIDMAETKGYRVW----------------------------------SAEVERGDDVH-----------------RFAQSKLVEATEKGEASASALGAVYGPGVALNNRDPVVDFSVCGSRTTTRITTLHSTLQLCP--YLVARLD 1251
            LN     +D  R DL           +S  W L +LF+S WD+R+PRDANGL+VLDESP+C KHL+ AL    GA   D     P+  +  G    TR P        S +  + D+L              YRASRDGW  + FH  CG DSP+T+TL+R+  ++    +  +++G FS    +   +     + SP  F+ ++     DGS SF P+K        RRG    +      P F  DL + LH++          NA++ L     AF V E  +F    G  + E + +RV                                   +A     DDV                  R A ++L +   K   S +AL AVYGP VA    D VV+ SV      TR+TTL STLQ CP   L AR D
Sbjct:   35 LNAAWDGIDKHRGDLEARMVEVDGDGISPTWNLCDLFESMWDKRIPRDANGLIVLDESPICVKHLLRALLKKSGAAALDS----PFGCSGQGWLR-TRWPTSPRSWRLSEVCPLTDILQGWCPGNPSRLHLIYRASRDGWGGEAFHECCGKDSPVTITLFRVLSSAGTA-VTDTIVGGFSRSSWS---NSCPFSRFSPDAFICMVKYGSADGSSSFQPSKWI-----PRRGLPNYLGTSSHGPCFGSDLCMSLHDD----------NARF-LHVAIGAFNVSEDSAFFTLGGQTVKEIEVFRVCREATAGSPPPPPRAKPATTSENGLIDLTSGGPSDAATESYDDDVRMSGALIAESLMEERAALREAFAELAQPNTKAGESVNALTAVYGPDVAAGKEDTVVELSV----RETRLTTLRSTLQACPDSALAARFD 442