EsuBft1017_14 (polypeptide) Ectocarpus subulatus male Bft15b

Query:    1 MAVARGRQGNLAHHLSSQAQRRLSXXXXXXXAGDFLLGRGHHAAGGHANLSSPSASSSSLGCFAPSPACISTSATGDDSSAWRHGSSXXXXXNAGSGGSFIRCEGGVAIASAPLRRAFSARGSTTPGSAVAAASSGRQGKQRGWGETEAAASAGGRWREFASASNPPKQYLRYIHRVKPDAEDPAAGESTPGSSPAGDGENDGQAEGGGGAKGAPGLRAEGVGEEEAEGADDEGAWQERAGNEMSRRWLESFHAEDILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRKEVIGMFTSRDLLGELARYPNKADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGLDPGQNRSGWKQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMRGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVINKADSTAEAVSTRGVAKDVQTVHEAAAA 783
            MAVARGRQGNLAHHLSSQAQRRLSXXXXXXXAGDFLLGRGHHAAGGHANLSSPSASSSSLGCFAPSPACISTSATGDDSSAWRHGSSXXXXXNAGSGGSFIRCEGGVAIASAPLRRAFSARGSTTPGSAVAAASSGRQGKQRGWGETEAAASAGGRWREFASASNPPKQYLRYIHRVKPDAEDPAAGESTPGSSPAGDGENDGQAEGGGGAKGAPGLRAEGVGEEEAEGADDEGAWQERAGNEMSRRWLESFHAEDILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRKEVIGMFTSRDLLGELARYPNKADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGLDPGQNRSGWKQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMRGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVINKADSTAEAVSTRGVAKDVQTVHEAAAA
Sbjct:    1 MAVARGRQGNLAHHLSSQAQRRLSXXXXXXXAGDFLLGRGHHAAGGHANLSSPSASSSSLGCFAPSPACISTSATGDDSSAWRHGSSXXXXXNAGSGGSFIRCEGGVAIASAPLRRAFSARGSTTPGSAVAAASSGRQGKQRGWGETEAAASAGGRWREFASASNPPKQYLRYIHRVKPDAEDPAAGESTPGSSPAGDGENDGQAEGGGGAKGAPGLRAEGVGEEEAEGADDEGAWQERAGNEMSRRWLESFHAEDILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRKEVIGMFTSRDLLGELARYPNKADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGLDPGQNRSGWKQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMRGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVINKADSTAEAVSTRGVAKDVQTVHEAAAA 783          

Query:  244 MSRRWLESFHAEDILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRKEVIGMFTSRDLLGELARYPNKADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGLDPGQNRSGWKQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMRGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVINKADSTAEAVSTRGVAKDVQTVHEAAAA 783
            M+RRWLESFHAEDILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRKEVIGMFTSRDLLGELARYPNKADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAY+KNISQRKGLPKGVGLDPGQNRSGWKQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDA+FVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEK  VVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDS+VAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNA FETPRDAVNTSFPVRPGDIIILATDGLFDNMELE ISSVALEWETKWFGGPM GLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMP  ITVVALRVINKADST+EAVSTRGVAK VQTVHEAAAA
Sbjct:    1 MTRRWLESFHAEDILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRKEVIGMFTSRDLLGELARYPNKADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYMKNISQRKGLPKGVGLDPGQNRSGWKQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAYFVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEK--VVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSNVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNANFETPRDAVNTSFPVRPGDIIILATDGLFDNMELENISSVALEWETKWFGGPMGGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPYYITVVALRVINKADSTSEAVSTRGVAKHVQTVHEAAAA 538          

Query:  265 RQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRR-----KEVIGMFTSRDLLGELARYPNKADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGLDPGQNRSGWKQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMR--GL--NEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVI 755
            R+  ++    T++EAI    +    + +V N R     KEV+G+FT++D++  L++  +KA+AL++     M P+SR+IY S  D+L +   +M EL++R LPV+ +G + GI+ + D+ +  +S EE+GGKKA+IK ++ R GLP G  +     + G K++    VG  ALPHP K  DG V+A+ R H   + A D  LSEDA FVL++ WP E  D   YVG+ADGVGSWR  GVDPRE+SHRLM    ++I SM+P +       +  P  +P +VL +AWE    EK  VVGSSTAC+A LD +L QLSF N+GD G++++RHIDSDVAGYMR+K TPR LR +D R+AF+S+QQLRSFNLPYQ GYTN   +N  F+TP DA N+S P+  GD+II+ TDGLFDN+EL+ I S+AL WE KWFG      GL  ++    ++++LA TL  RARELSLD  RDSPFA+LAKENDIMWGGGMPDD T+ A+RV+
Sbjct:  159 RKVCQISSGATLEEAIKILASNNANTSMVYNERTPGGAKEVVGIFTAQDVIKTLSKQADKAEALQSLVKNAMTPMSRVIYCSPDDTLEKVQYIMVELQIRTLPVVKDGVIYGIITLGDVINHHYSSEEIGGKKAFIKGVAGRLGLPSGTQVASHVVKEGVKKSIKWKVGVAALPHPFKRRDG-VAASLRLHGPKDYATDLDLSEDASFVLNLPWPHEHGDEATYVGIADGVGSWREHGVDPREYSHRLMQLCEQFIRSMAPKAPN-----LVTPMVRPLDVLSSAWETITKEK--VVGSSTACIATLDMELNQLSFCNVGDSGIIIMRHIDSDVAGYMRDKTTPRPLRTNDFRIAFVSRQQLRSFNLPYQMGYTNTQPENC-FDTPSDADNSSIPIMRGDVIIMGTDGLFDNVELDEICSIALAWEQKWFGSGAHSSGLRASDFPEESVQELAMTLCRRARELSLDQKRDSPFAILAKENDIMWGGGMPDDCTIFAMRVV 649          

Query:  458 DPTLSEDAHFVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPP--PPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMRGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVINKADS 760
            DPTLSEDAHFVL VAW T   +++ YVG+ADGVGSWR +GVDPREF  RLM WA++YI+S +P   + G  V+  P   PKP EVL AAWE  +GEKA  VGSSTAC+A LDY L+QL+FSNIGD GVVVLRHIDSD+AGYMRE++TPRHLR SDLR+AFISQQQLRSFNLPYQ GYTNVP     FETPRDAVNTSFP+ PGDI+ILATDGL+DNMEL+ +  +A EWETKWFGG MRGL++ +NAA  DLA  L  RARELSLD +RDSPFALLAKENDIMWGGGMPDD+TVV +R++NK  S
Sbjct:    2 DPTLSEDAHFVLSVAWATPEAESLQYVGIADGVGSWRGLGVDPREFPQRLMFWAQQYILSTAPS--VSGSAVVDQPRPAPKPLEVLSAAWEMVMGEKA--VGSSTACIATLDYSLDQLTFSNIGDNGVVVLRHIDSDIAGYMRERRTPRHLRTSDLRIAFISQQQLRSFNLPYQLGYTNVPAGGT-FETPRDAVNTSFPIMPGDIVILATDGLYDNMELDEMCDIAQEWETKWFGGAMRGLDKQDNAAAADLAARLAQRARELSLDTSRDSPFALLAKENDIMWGGGMPDDVTVVVMRIVNKLSS 301          

Query:  243 EMSRRWLESFHAEDILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRKEVIGMFTSRDLLGELARYPNKADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAE-GKVMGIVNVNDISDFS--FSMEELGGKKAYIKNISQRKGLPKGVGLDPGQNRSGW-----------------------------------------KQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYM-REKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNAK-FETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMRGL-----NEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVI 755
            E  +  +E     D+L    ++ +   V  D +++ AI   V  +    +V     +V+G+FT+RD+L ++ ++P+++ AL T  HE M P SR++Y +  D++    L+M  L VRN+PV+ E G V GI+     +D S  F  +++GGK A++++I   +GLP G  L   Q    +                                         ++     VG  ALPHP K  DG  +  +      EV  D  LSED+HF+  V WPT  +D V YVG+ADGVGSWR  GVDPR+FS RLMH   +Y+ S +P   +      +P P  P EVL  AWE    EK  +VGS TAC+  LD+ + QLS++N+GD G+++LRHIDS+VAG + R + TPR  R SDLR+AF+SQQQLRSFNLPYQ GY        + FE P DA  T +  RPGDI+I+ATDGLFDN+EL+ I S+A EWETKWFGG   G      +     AL DLA+TL  R+RE SLDN+RDSPFA+LAK+NDI+W GGMPDD TV+ALRV+
Sbjct:   77 ERDKNHVERLRVADVL---DMMTEVTAVHRDVSLNHAIEVLVIHRKGVLLVEGDDGDVLGIFTTRDVLQQIVQFPDRSMALCTSVHEIMTPASRIVYCTPADTVKHVRLLMRSLGVRNVPVVDEHGVVRGIMTAKLAADHSSFFRAKDVGGKAAFMQHIEGHRGLPMGTKLSSDQGLQSFSTLPNDVTSVIDADDEEAIDEYLSVLQKREQAQGRKLLPLRRRRLDLHVGLAALPHPFKRPDGVANTRRDYGPGEEVCTDVRLSEDSHFMSRVRWPTPFSDFVTYVGVADGVGSWRLRGVDPRDFSQRLMHCCAKYLNSSAPEESLSNTDEYTPHP-SPLEVLQRAWEMVTREK--IVGSCTACIVTLDHQMSQLSYANLGDSGLIILRHIDSEVAGTVYRNRTTPRSDRTSDLRIAFLSQQQLRSFNLPYQLGYVGDEGGRGQVFEEPTDANVTGYSTRPGDIVIVATDGLFDNVELDEICSLAFEWETKWFGGANEGKALPGDDSTETEALNDLAKTLCDRSREFSLDNSRDSPFAILAKDNDILWSGGMPDDCTVLALRVV 634          

Query:  257 ILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRKEVIGMFTSRDLLGELARYPNKADALKTRAH-------------EFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGLDPGQNRSGWKQT---------------------------------FSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLD-VAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYI---VSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGY-TNVPEDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMRG--------LNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVI 755
            +L  K+   +  EV  D TV E +     +   S V+ N  K V+G+ TSRD+L  L    +  D  +  A              E + P+  M++A A DSL +C ++MSE ++RNLPV+ +G ++G+V   D+ D++F  EELGGK ++IKNI+ R GLP GV +   +  S  K                                    S  V A  LPHP K+ DG  + + RE+   E A DP LS+DA+FV+D +A P +  D V  VG+ADGVG WR  G +   FSH LM  A+E +    S    S   G  +    P +P +VL AAW+ T+  +  + GS+TA VA LD +L QLSFSN+GD G+VVLRHIDS VAGYMRE+ TPRHLR SDLR+AF SQQQL++FNLPYQ GY     E   +FETPR A  TSFPV PGD II+ATDGLFDN+EL+ + +  L WE K FGG  +         LNE     +++LA+     AR+ ++D+ RD PFA+LAKENDIMW GGMPDDITVV +RV+
Sbjct:   77 LLAQKSFKNRSAEVSDDITVAEGMRLLGEKGQGSLVLYNEEKAVVGIITSRDVLRSLVMGSDVGDPQEPAALAQEMPERLARPLLELVTPVETMVFAKASDSLARCQIIMSERRIRNLPVVDDGAIVGLVTAKDLMDYTFEPEELGGKASFIKNIATRSGLPAGVRVKLDEQESSSKIAEDARRGDHFFFSMFRNRVAGAKSARATEPITPGISVRVAAKMLPHPFKLADGYCANSLREYGPGEFASDPRLSDDAYFVIDQLACPHQHGDAVTVVGVADGVGEWRLKGYNSGAFSHNLMQAAKESVENFASSVQASVKRGTALSEQHPIRPLDVLKAAWKETLEHR--IPGSATALVATLDTELNQLSFSNVGDAGIVVLRHIDSTVAGYMRERTTPRHLRQSDLRVAFQSQQQLKAFNLPYQLGYFPGEEEGKTRFETPRHADTTSFPVLPGDTIIIATDGLFDNVELDELCAATLAWEKKHFGGEKKRDLAKSGATLNEVPEQVMQELAKDFCSLARKHAVDDQRDGPFAMLAKENDIMWSGGMPDDITVVVMRVL 632          

Query:  256 DILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRK-EVIGMFTSRDLL----GELARYPN--KADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGLD--------PGQNRSGWKQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVA-------WPTETTDTVN--YVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPP--PPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPE-DNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFG----GPMRGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVI 755
            DILR  T+  +   +    TV +A+   V++K+ S +VV+     V+G+FT+RDLL      ++  P         T+  E M    ++++ S  D++ +C  +M + K+RN+PVI +G V GI+ +  ++D SF+++++GGKK +I N++ R+GLP  V +         PG + +       A +G  ALPHP K  +GGV+ ++R +   ++A D +L EDA F L V+        P       +  Y+ +ADGVGSWR+  VDPR +SH L+  A++ I +      +  +        P  P +V+M AW  T    A + G+ST CVA LD  L QLS+SN+GDCG++V+RHIDS+ AGYMRE++ PRHLR +DLR+A++SQQQLR+FNLPYQ G++N+PE  NA FE+P DA   S PV PGD+I+LATDGLFDN++L+ I  +  +WE + F       +   +   N A++ LAE L   ARE+SLD  RDSPFA+LAKENDIMWGGGMPDD TV+  R++
Sbjct:   84 DILR--TVENKNFTISSSATVADAVAHLVDEKLASNLVVSPESGAVLGIFTARDLLKFIKATISANPRGLNESMTSTKVTEVMTRREKLVHCSPDDTVKRCREIMFQCKIRNMPVIEDGIVKGILTMKLLADSSFNLQDIGGKKGFIHNVTGRRGLPDSVKVQKISTVIEGPGGSGAVAITKLDAEIGMFALPHPFKRAEGGVAMDRRHYGPSDLATDLSLIEDASFALRVSEKDPSRPLPLSALSEPSQIYLCVADGVGSWRQYNVDPRLYSHALVDNAQKIIAADFQHRALIHDSPFQSDLDPIHPLDVIMDAWNLTTS--AEINGASTICVATLDKKLSQLSYSNLGDCGLMVVRHIDSETAGYMRERQMPRHLRKNDLRIAYLSQQQLRAFNLPYQLGFSNIPEVSNASFESPSDADTASIPVMPGDVIVLATDGLFDNVDLDEIVGIIADWEARHFSPATEDSVNARSSKGNEAVQALAEQLVRMAREVSLDTHRDSPFAILAKENDIMWGGGMPDDTTVIVARIV 610          

Query:  256 DILRDKTLLRQ-QLEVRGDCTVDEAITAFVNQKVTSFVVVNR----------RKEVIGMFTSRDLLGELAR-YPNKADA---LKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGL--DPGQNRSGW---KQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTDT-----------------VNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYM-REKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTN---VPEDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMRG---------------LNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVINK 757
            +IL+ K  LR  +  +    TV  AI   +   ++  +VV+R          R  V+GM TSRDLL  +A  + N   A   +      FM P+S++IYA  ++++  C  +M++L ++ LPV++ G+V G+V   D+SD+    ++ GGKK Y+++IS+R GL     +   P   R+     ++    +VG   +PHP K   GG   N R+    ++  DP +SEDA+FV++    TE  D                  V Y+G+ADGVGSWR  GVDPREFSHRLM      +   +  S +            P  VL  A+E    ++ +++GSSTACV   D    QL FSN+GD G++VLRHIDS+VAG + R++KTPR  R SD+R+AF+SQQQL+SFN P+Q G+T       D + F+T  D+  +S  VR GDII++ATDGLFDN++++ I+ +ALEWE +   G +RG               + + +   + +LAE L  +ARE SLDN+ DSPFA+LAKENDIMW GGMPDD TV+A+ ++ +
Sbjct:  142 EILKAKHTLRWVEPVICHTSTVKTAIQTCIEGNLSGMMVVDRDETTSESSRERGRVVGMTTSRDLLRMMAAGFKNNEGAEEVMNKTVGNFMTPISQVIYARPEETVGTCRAIMAKLGIKCLPVLSHGRVEGLVTARDMSDYGVEAKDRGGKKNYLRDISERVGLSSNTSMAEPPTYLRAHLALEQKPLFMNVGVAEMPHPFKTGGGGCGMNARDFGPRDLTTDPDMSEDAYFVME----TEMVDNNEGSGSEDEDVVVTKRPVVYMGVADGVGSWREYGVDPREFSHRLMEECENLLREATNKSRVI----------TPSTVLANAFERV--KEENIIGSSTACVGLFDSVRHQLHFSNLGDSGIIVLRHIDSNVAGALKRDRKTPRVQRKSDIRIAFVSQQQLKSFNHPFQLGWTGEDIAESDGSSFKTAADSCASSIHVRRGDIILMATDGLFDNVDIDDIAEIALEWEQR--NGFIRGGDISAREKRWAAGASMTDLSCEKVTELAEMLCIKARENSLDNSVDSPFAILAKENDIMWSGGMPDDCTVIAMHIVGE 681          

Query:  329 EFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIA-EGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGL-DPG---QNRSGWKQT-FSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTDT---VNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYM-REKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTN--VPED-NAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWET---------------KWFGGPMRGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVINKADSTAEAVSTRGV 770
            +FM P+++++YA  ++++  C  +M++L ++ +P+++ EG+V G++   D+SD+    +E GGK +Y++++SQR GL     + DP    ++    +Q+   A++G   LPHP K T+ GV  N R+    + +D+P  SED+HFV  +    +  D      Y+G+ADGVGSWR   VDPR+FSH+LM      +     G     +         P E+L  A+E    E  +++GSSTACVA  D    QL FSN+GD G++VLRHIDSD AG + R + TPR  R SDLR+AF+SQQQLRSFN PYQ G+T   +PED ++ F+T  D+  +S  +R GDIII+ TDGLFDN++++ I  +ALEWE                +W  G    L + ++  +  LA+ L  +ARELSLD++ DSPFALLAKENDIMW GGMPDD TVVA+ V+ ++   AE   T G+
Sbjct:   12 DFMTPITQVVYARPEETIGMCRTIMAKLGIKCIPILSHEGRVEGLITARDMSDYGLEAKEKGGKTSYLRDVSQRVGLSSNTSMADPPPYLRSHLALEQSPLFANIGVAELPHPFK-TESGVGMNHRDFGPHDFSDNPEWSEDSHFVTTINLRDDQGDKKRPFTYMGVADGVGSWREYDVDPRDFSHKLMEECENIL--REAGGRRTDDSTKFRRMIAPAEILAQAYERVKAE--NIIGSSTACVALFDNVRHQLHFSNLGDSGIIVLRHIDSDTAGTLKRNRDTPRSERSSDLRVAFVSQQQLRSFNHPYQLGWTGEELPEDEDSSFKTASDSCTSSIHLRRGDIIIMGTDGLFDNVDIDDICKIALEWEQAHGFLRAGDIVAREKRWAMG--NSLTQLSHDEIPSLAQRLCQKARELSLDSSIDSPFALLAKENDIMWSGGMPDDCTVVAMHVVGRS---AEDTMTEGL 471          

Query:  243 EMSRRWLESFHAEDILRDKTLLRQQLEVRG-DCTVDEAITAFVNQKVTSFVVVNRRKE---------------VIGMFTSRDLLGELA---RYPNKADA--LKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIA-EGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGL-DPGQNRSGW----KQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTD---TVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIV-SMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYM-REKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVP---EDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWET---------------KWFGGPMRGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVINKA 758
            E+ RR +      ++L  K   R    V   D T+  AI   +   ++  +V+   K                V+G+ TSRDLL  +A   +  N  D   +     ++M P+S++IY    +++  C  +MS+L ++ LP+++ EGKV G++   D++D+  S  + GGKK+Y+ ++S+R GL     + +P    +      ++  S ++G   LPHP+K  DG V  N+R+H   ++A D  LSEDA+F   V    E       V Y G+ADGVGSWR+ GVDPR FSH+LM      ++ +      IGG       PP   +++  A+E    E  +++GSSTACVA  D    QL FSN+GD G++VLRHIDSD+AG + R++ TPR  R SDLR+AFISQQQL SFN PYQ G+T      +++  F+T RD+  TS  +R GDIII+ATDGLFDN++++ I+ +AL+WE                +W  G    L   ++  +  LA  L  +ARE SLD+++DSPFALLAK+NDIMW GGMPDD TV+   V+ ++
Sbjct:    1 EVKRRRVADVPIREVLDSKHAYRWVNPVISEDATIRNAIPTVIEGGLSGMMVIEAPKNPSEKDKNNHTESPRRVVGLLTSRDLLRMMAAGFKDENITDEEIVNKVIGDYMTPMSQVIYGRPTETIGMCRSLMSKLGIKCLPILSKEGKVEGLITARDMNDYGLSASDRGGKKSYLNDVSERVGLSSDTSMAEPPLYMNAHLALEQKPLSVNMGVDELPHPYKTHDG-VGHNRRDHGPQDLATDLDLSEDAYFCTRVHLEDENDQFLRDVTYFGVADGVGSWRQYGVDPRLFSHKLMEECENILLEACHRDKDIGGGKFRRVIPPA--DIIAQAYERVKAE--NIIGSSTACVALFDCIRHQLHFSNLGDSGIIVLRHIDSDIAGTLKRDRITPRAERSSDLRVAFISQQQLFSFNHPYQVGWTGEELSTDEHTSFKTARDSCTTSIHLRRGDIIIMATDGLFDNVDIDDITKIALKWEQGVGLIRGGDIAAREQRWAMG--NSLTILSSEKVGSLASELCEKARENSLDSSKDSPFALLAKDNDIMWSGGMPDDCTVIVAHVVGRS 559          

Query:  257 MAVARGRQGNLAHHLSSQAQRRLSXXXXXXXAGDFLLGRGHHAAGGHANLSSPSASSSSLGCFAPSPACISTSATGDDSSAWRHGSSXXXXXNAGSGGSFIRCEGGVAIASAPLRRAFSARGSTTPGSAVAAASSGRQGKQRGWGETEAAASAGGRWREFASASNPPKQYLRYIHRVKPDAEDPAAGESTPGSSPAGDGENDGQAEGGGGAKGAPGLRAEGVGEEEAEGADDEGAWQERAGNEMSRRWLESFHAEDILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRKEVIGMFTSRDLLGELARYPNKADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGLDPGQNRSGWKQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMRGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVINKADSTAEAVSTRGVAKDVQTVHEAAAA 2605
            MAVARGRQGNLAHHLSSQAQRRLSXXXXXXXAGDFLLGRGHHAAGGHANLSSPSASSSSLGCFAPSPACISTSATGDDSSAWRHGSSXXXXXNAGSGGSFIRCEGGVAIASAPLRRAFSARGSTTPGSAVAAASSGRQGKQRGWGETEAAASAGGRWREFASASNPPKQYLRYIHRVKPDAEDPAAGESTPGSSPAGDGENDGQAEGGGGAKGAPGLRAEGVGEEEAEGADDEGAWQERAGNEMSRRWLESFHAEDILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRKEVIGMFTSRDLLGELARYPNKADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGLDPGQNRSGWKQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMRGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVINKADSTAEAVSTRGVAKDVQTVHEAAAA
Sbjct:    1 MAVARGRQGNLAHHLSSQAQRRLSXXXXXXXAGDFLLGRGHHAAGGHANLSSPSASSSSLGCFAPSPACISTSATGDDSSAWRHGSSXXXXXNAGSGGSFIRCEGGVAIASAPLRRAFSARGSTTPGSAVAAASSGRQGKQRGWGETEAAASAGGRWREFASASNPPKQYLRYIHRVKPDAEDPAAGESTPGSSPAGDGENDGQAEGGGGAKGAPGLRAEGVGEEEAEGADDEGAWQERAGNEMSRRWLESFHAEDILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRKEVIGMFTSRDLLGELARYPNKADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGLDPGQNRSGWKQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMRGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVINKADSTAEAVSTRGVAKDVQTVHEAAAA 783          

Query:  986 MSRRWLESFHAEDILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRKEVIGMFTSRDLLGELARYPNKADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGLDPGQNRSGWKQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMRGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVINKADSTAEAVSTRGVAKDVQTVHEAAAA 2605
            M+RRWLESFHAEDILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRKEVIGMFTSRDLLGELARYPNKADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAY+KNISQRKGLPKGVGLDPGQNRSGWKQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDA+FVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEK  VVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDS+VAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNA FETPRDAVNTSFPVRPGDIIILATDGLFDNMELE ISSVALEWETKWFGGPM GLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMP  ITVVALRVINKADST+EAVSTRGVAK VQTVHEAAAA
Sbjct:    1 MTRRWLESFHAEDILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRKEVIGMFTSRDLLGELARYPNKADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYMKNISQRKGLPKGVGLDPGQNRSGWKQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAYFVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEK--VVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSNVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNANFETPRDAVNTSFPVRPGDIIILATDGLFDNMELENISSVALEWETKWFGGPMGGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPYYITVVALRVINKADSTSEAVSTRGVAKHVQTVHEAAAA 538          

Query: 1049 RQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRR-----KEVIGMFTSRDLLGELARYPNKADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGLDPGQNRSGWKQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMR--GL--NEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVI 2521
            R+  ++    T++EAI    +    + +V N R     KEV+G+FT++D++  L++  +KA+AL++     M P+SR+IY S  D+L +   +M EL++R LPV+ +G + GI+ + D+ +  +S EE+GGKKA+IK ++ R GLP G  +     + G K++    VG  ALPHP K  DG V+A+ R H   + A D  LSEDA FVL++ WP E  D   YVG+ADGVGSWR  GVDPRE+SHRLM    ++I SM+P +       +  P  +P +VL +AWE    EK  VVGSSTAC+A LD +L QLSF N+GD G++++RHIDSDVAGYMR+K TPR LR +D R+AF+S+QQLRSFNLPYQ GYTN   +N  F+TP DA N+S P+  GD+II+ TDGLFDN+EL+ I S+AL WE KWFG      GL  ++    ++++LA TL  RARELSLD  RDSPFA+LAKENDIMWGGGMPDD T+ A+RV+
Sbjct:  159 RKVCQISSGATLEEAIKILASNNANTSMVYNERTPGGAKEVVGIFTAQDVIKTLSKQADKAEALQSLVKNAMTPMSRVIYCSPDDTLEKVQYIMVELQIRTLPVVKDGVIYGIITLGDVINHHYSSEEIGGKKAFIKGVAGRLGLPSGTQVASHVVKEGVKKSIKWKVGVAALPHPFKRRDG-VAASLRLHGPKDYATDLDLSEDASFVLNLPWPHEHGDEATYVGIADGVGSWREHGVDPREYSHRLMQLCEQFIRSMAPKAPN-----LVTPMVRPLDVLSSAWETITKEK--VVGSSTACIATLDMELNQLSFCNVGDSGIIIMRHIDSDVAGYMRDKTTPRPLRTNDFRIAFVSRQQLRSFNLPYQMGYTNTQPENC-FDTPSDADNSSIPIMRGDVIIMGTDGLFDNVELDEICSIALAWEQKWFGSGAHSSGLRASDFPEESVQELAMTLCRRARELSLDQKRDSPFAILAKENDIMWGGGMPDDCTIFAMRVV 649          

Query: 1628 DPTLSEDAHFVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPP--PPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMRGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVINKADS 2536
            DPTLSEDAHFVL VAW T   +++ YVG+ADGVGSWR +GVDPREF  RLM WA++YI+S +P   + G  V+  P   PKP EVL AAWE  +GEKA  VGSSTAC+A LDY L+QL+FSNIGD GVVVLRHIDSD+AGYMRE++TPRHLR SDLR+AFISQQQLRSFNLPYQ GYTNVP     FETPRDAVNTSFP+ PGDI+ILATDGL+DNMEL+ +  +A EWETKWFGG MRGL++ +NAA  DLA  L  RARELSLD +RDSPFALLAKENDIMWGGGMPDD+TVV +R++NK  S
Sbjct:    2 DPTLSEDAHFVLSVAWATPEAESLQYVGIADGVGSWRGLGVDPREFPQRLMFWAQQYILSTAPS--VSGSAVVDQPRPAPKPLEVLSAAWEMVMGEKA--VGSSTACIATLDYSLDQLTFSNIGDNGVVVLRHIDSDIAGYMRERRTPRHLRTSDLRIAFISQQQLRSFNLPYQLGYTNVPAGGT-FETPRDAVNTSFPIMPGDIVILATDGLYDNMELDEMCDIAQEWETKWFGGAMRGLDKQDNAAAADLAARLAQRARELSLDTSRDSPFALLAKENDIMWGGGMPDDVTVVVMRIVNKLSS 301          

Query:  983 EMSRRWLESFHAEDILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRKEVIGMFTSRDLLGELARYPNKADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAE-GKVMGIVNVNDISDFS--FSMEELGGKKAYIKNISQRKGLPKGVGLDPGQNRSGW-----------------------------------------KQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYM-REKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPEDNAK-FETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMRGL-----NEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVI 2521
            E  +  +E     D+L    ++ +   V  D +++ AI   V  +    +V     +V+G+FT+RD+L ++ ++P+++ AL T  HE M P SR++Y +  D++    L+M  L VRN+PV+ E G V GI+     +D S  F  +++GGK A++++I   +GLP G  L   Q    +                                         ++     VG  ALPHP K  DG  +  +      EV  D  LSED+HF+  V WPT  +D V YVG+ADGVGSWR  GVDPR+FS RLMH   +Y+ S +P   +      +P P  P EVL  AWE    EK  +VGS TAC+  LD+ + QLS++N+GD G+++LRHIDS+VAG + R + TPR  R SDLR+AF+SQQQLRSFNLPYQ GY        + FE P DA  T +  RPGDI+I+ATDGLFDN+EL+ I S+A EWETKWFGG   G      +     AL DLA+TL  R+RE SLDN+RDSPFA+LAK+NDI+W GGMPDD TV+ALRV+
Sbjct:   77 ERDKNHVERLRVADVL---DMMTEVTAVHRDVSLNHAIEVLVIHRKGVLLVEGDDGDVLGIFTTRDVLQQIVQFPDRSMALCTSVHEIMTPASRIVYCTPADTVKHVRLLMRSLGVRNVPVVDEHGVVRGIMTAKLAADHSSFFRAKDVGGKAAFMQHIEGHRGLPMGTKLSSDQGLQSFSTLPNDVTSVIDADDEEAIDEYLSVLQKREQAQGRKLLPLRRRRLDLHVGLAALPHPFKRPDGVANTRRDYGPGEEVCTDVRLSEDSHFMSRVRWPTPFSDFVTYVGVADGVGSWRLRGVDPRDFSQRLMHCCAKYLNSSAPEESLSNTDEYTPHP-SPLEVLQRAWEMVTREK--IVGSCTACIVTLDHQMSQLSYANLGDSGLIILRHIDSEVAGTVYRNRTTPRSDRTSDLRIAFLSQQQLRSFNLPYQLGYVGDEGGRGQVFEEPTDANVTGYSTRPGDIVIVATDGLFDNVELDEICSLAFEWETKWFGGANEGKALPGDDSTETEALNDLAKTLCDRSREFSLDNSRDSPFAILAKDNDILWSGGMPDDCTVLALRVV 634          

Query: 1025 ILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRKEVIGMFTSRDLLGELARYPNKADALKTRAH-------------EFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGLDPGQNRSGWKQT---------------------------------FSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLD-VAWPTETTDTVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYI---VSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGY-TNVPEDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMRG--------LNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVI 2521
            +L  K+   +  EV  D TV E +     +   S V+ N  K V+G+ TSRD+L  L    +  D  +  A              E + P+  M++A A DSL +C ++MSE ++RNLPV+ +G ++G+V   D+ D++F  EELGGK ++IKNI+ R GLP GV +   +  S  K                                    S  V A  LPHP K+ DG  + + RE+   E A DP LS+DA+FV+D +A P +  D V  VG+ADGVG WR  G +   FSH LM  A+E +    S    S   G  +    P +P +VL AAW+ T+  +  + GS+TA VA LD +L QLSFSN+GD G+VVLRHIDS VAGYMRE+ TPRHLR SDLR+AF SQQQL++FNLPYQ GY     E   +FETPR A  TSFPV PGD II+ATDGLFDN+EL+ + +  L WE K FGG  +         LNE     +++LA+     AR+ ++D+ RD PFA+LAKENDIMW GGMPDDITVV +RV+
Sbjct:   77 LLAQKSFKNRSAEVSDDITVAEGMRLLGEKGQGSLVLYNEEKAVVGIITSRDVLRSLVMGSDVGDPQEPAALAQEMPERLARPLLELVTPVETMVFAKASDSLARCQIIMSERRIRNLPVVDDGAIVGLVTAKDLMDYTFEPEELGGKASFIKNIATRSGLPAGVRVKLDEQESSSKIAEDARRGDHFFFSMFRNRVAGAKSARATEPITPGISVRVAAKMLPHPFKLADGYCANSLREYGPGEFASDPRLSDDAYFVIDQLACPHQHGDAVTVVGVADGVGEWRLKGYNSGAFSHNLMQAAKESVENFASSVQASVKRGTALSEQHPIRPLDVLKAAWKETLEHR--IPGSATALVATLDTELNQLSFSNVGDAGIVVLRHIDSTVAGYMRERTTPRHLRQSDLRVAFQSQQQLKAFNLPYQLGYFPGEEEGKTRFETPRHADTTSFPVLPGDTIIIATDGLFDNVELDELCAATLAWEKKHFGGEKKRDLAKSGATLNEVPEQVMQELAKDFCSLARKHAVDDQRDGPFAMLAKENDIMWSGGMPDDITVVVMRVL 632          

Query: 1022 DILRDKTLLRQQLEVRGDCTVDEAITAFVNQKVTSFVVVNRRK-EVIGMFTSRDLL----GELARYPN--KADALKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGLD--------PGQNRSGWKQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVA-------WPTETTDTVN--YVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPP--PPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYMREKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVPE-DNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFG----GPMRGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVI 2521
            DILR  T+  +   +    TV +A+   V++K+ S +VV+     V+G+FT+RDLL      ++  P         T+  E M    ++++ S  D++ +C  +M + K+RN+PVI +G V GI+ +  ++D SF+++++GGKK +I N++ R+GLP  V +         PG + +       A +G  ALPHP K  +GGV+ ++R +   ++A D +L EDA F L V+        P       +  Y+ +ADGVGSWR+  VDPR +SH L+  A++ I +      +  +        P  P +V+M AW  T    A + G+ST CVA LD  L QLS+SN+GDCG++V+RHIDS+ AGYMRE++ PRHLR +DLR+A++SQQQLR+FNLPYQ G++N+PE  NA FE+P DA   S PV PGD+I+LATDGLFDN++L+ I  +  +WE + F       +   +   N A++ LAE L   ARE+SLD  RDSPFA+LAKENDIMWGGGMPDD TV+  R++
Sbjct:   84 DILR--TVENKNFTISSSATVADAVAHLVDEKLASNLVVSPESGAVLGIFTARDLLKFIKATISANPRGLNESMTSTKVTEVMTRREKLVHCSPDDTVKRCREIMFQCKIRNMPVIEDGIVKGILTMKLLADSSFNLQDIGGKKGFIHNVTGRRGLPDSVKVQKISTVIEGPGGSGAVAITKLDAEIGMFALPHPFKRAEGGVAMDRRHYGPSDLATDLSLIEDASFALRVSEKDPSRPLPLSALSEPSQIYLCVADGVGSWRQYNVDPRLYSHALVDNAQKIIAADFQHRALIHDSPFQSDLDPIHPLDVIMDAWNLTTS--AEINGASTICVATLDKKLSQLSYSNLGDCGLMVVRHIDSETAGYMRERQMPRHLRKNDLRIAYLSQQQLRAFNLPYQLGFSNIPEVSNASFESPSDADTASIPVMPGDVIVLATDGLFDNVDLDEIVGIIADWEARHFSPATEDSVNARSSKGNEAVQALAEQLVRMAREVSLDTHRDSPFAILAKENDIMWGGGMPDDTTVIVARIV 610          

Query: 1022 DILRDKTLLRQ-QLEVRGDCTVDEAITAFVNQKVTSFVVVNR----------RKEVIGMFTSRDLLGELAR-YPNKADA---LKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIAEGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGL--DPGQNRSGW---KQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTDT-----------------VNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYM-REKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTN---VPEDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWETKWFGGPMRG---------------LNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVINK 2527
            +IL+ K  LR  +  +    TV  AI   +   ++  +VV+R          R  V+GM TSRDLL  +A  + N   A   +      FM P+S++IYA  ++++  C  +M++L ++ LPV++ G+V G+V   D+SD+    ++ GGKK Y+++IS+R GL     +   P   R+     ++    +VG   +PHP K   GG   N R+    ++  DP +SEDA+FV++    TE  D                  V Y+G+ADGVGSWR  GVDPREFSHRLM      +   +  S +            P  VL  A+E    ++ +++GSSTACV   D    QL FSN+GD G++VLRHIDS+VAG + R++KTPR  R SD+R+AF+SQQQL+SFN P+Q G+T       D + F+T  D+  +S  VR GDII++ATDGLFDN++++ I+ +ALEWE +   G +RG               + + +   + +LAE L  +ARE SLDN+ DSPFA+LAKENDIMW GGMPDD TV+A+ ++ +
Sbjct:  142 EILKAKHTLRWVEPVICHTSTVKTAIQTCIEGNLSGMMVVDRDETTSESSRERGRVVGMTTSRDLLRMMAAGFKNNEGAEEVMNKTVGNFMTPISQVIYARPEETVGTCRAIMAKLGIKCLPVLSHGRVEGLVTARDMSDYGVEAKDRGGKKNYLRDISERVGLSSNTSMAEPPTYLRAHLALEQKPLFMNVGVAEMPHPFKTGGGGCGMNARDFGPRDLTTDPDMSEDAYFVME----TEMVDNNEGSGSEDEDVVVTKRPVVYMGVADGVGSWREYGVDPREFSHRLMEECENLLREATNKSRVI----------TPSTVLANAFERV--KEENIIGSSTACVGLFDSVRHQLHFSNLGDSGIIVLRHIDSNVAGALKRDRKTPRVQRKSDIRIAFVSQQQLKSFNHPFQLGWTGEDIAESDGSSFKTAADSCASSIHVRRGDIILMATDGLFDNVDIDDIAEIALEWEQR--NGFIRGGDISAREKRWAAGASMTDLSCEKVTELAEMLCIKARENSLDNSVDSPFAILAKENDIMWSGGMPDDCTVIAMHIVGE 681          

Query: 1241 EFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIA-EGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGL-DPG---QNRSGWKQT-FSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTDT---VNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIVSMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYM-REKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTN--VPED-NAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWET---------------KWFGGPMRGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVINKADSTAEAVSTRGV 2566
            +FM P+++++YA  ++++  C  +M++L ++ +P+++ EG+V G++   D+SD+    +E GGK +Y++++SQR GL     + DP    ++    +Q+   A++G   LPHP K T+ GV  N R+    + +D+P  SED+HFV  +    +  D      Y+G+ADGVGSWR   VDPR+FSH+LM      +     G     +         P E+L  A+E    E  +++GSSTACVA  D    QL FSN+GD G++VLRHIDSD AG + R + TPR  R SDLR+AF+SQQQLRSFN PYQ G+T   +PED ++ F+T  D+  +S  +R GDIII+ TDGLFDN++++ I  +ALEWE                +W  G    L + ++  +  LA+ L  +ARELSLD++ DSPFALLAKENDIMW GGMPDD TVVA+ V+ ++   AE   T G+
Sbjct:   12 DFMTPITQVVYARPEETIGMCRTIMAKLGIKCIPILSHEGRVEGLITARDMSDYGLEAKEKGGKTSYLRDVSQRVGLSSNTSMADPPPYLRSHLALEQSPLFANIGVAELPHPFK-TESGVGMNHRDFGPHDFSDNPEWSEDSHFVTTINLRDDQGDKKRPFTYMGVADGVGSWREYDVDPRDFSHKLMEECENIL--REAGGRRTDDSTKFRRMIAPAEILAQAYERVKAE--NIIGSSTACVALFDNVRHQLHFSNLGDSGIIVLRHIDSDTAGTLKRNRDTPRSERSSDLRVAFVSQQQLRSFNHPYQLGWTGEELPEDEDSSFKTASDSCTSSIHLRRGDIIIMGTDGLFDNVDIDDICKIALEWEQAHGFLRAGDIVAREKRWAMG--NSLTQLSHDEIPSLAQRLCQKARELSLDSSIDSPFALLAKENDIMWSGGMPDDCTVVAMHVVGRS---AEDTMTEGL 471          

Query:  983 EMSRRWLESFHAEDILRDKTLLRQQLEVRG-DCTVDEAITAFVNQKVTSFVVVNRRKE---------------VIGMFTSRDLLGELA---RYPNKADA--LKTRAHEFMIPLSRMIYASAKDSLYQCLLVMSELKVRNLPVIA-EGKVMGIVNVNDISDFSFSMEELGGKKAYIKNISQRKGLPKGVGL-DPGQNRSGW----KQTFSASVGAVALPHPHKMTDGGVSANKREHRHLEVADDPTLSEDAHFVLDVAWPTETTD---TVNYVGLADGVGSWRRVGVDPREFSHRLMHWAREYIV-SMSPGSGIGGEGVMSPPPPKPHEVLMAAWEYTIGEKASVVGSSTACVAALDYDLEQLSFSNIGDCGVVVLRHIDSDVAGYM-REKKTPRHLRDSDLRLAFISQQQLRSFNLPYQFGYTNVP---EDNAKFETPRDAVNTSFPVRPGDIIILATDGLFDNMELETISSVALEWET---------------KWFGGPMRGLNEHNNAALEDLAETLGHRARELSLDNTRDSPFALLAKENDIMWGGGMPDDITVVALRVINKA 2530
            E+ RR +      ++L  K   R    V   D T+  AI   +   ++  +V+   K                V+G+ TSRDLL  +A   +  N  D   +     ++M P+S++IY    +++  C  +MS+L ++ LP+++ EGKV G++   D++D+  S  + GGKK+Y+ ++S+R GL     + +P    +      ++  S ++G   LPHP+K  DG V  N+R+H   ++A D  LSEDA+F   V    E       V Y G+ADGVGSWR+ GVDPR FSH+LM      ++ +      IGG       PP   +++  A+E    E  +++GSSTACVA  D    QL FSN+GD G++VLRHIDSD+AG + R++ TPR  R SDLR+AFISQQQL SFN PYQ G+T      +++  F+T RD+  TS  +R GDIII+ATDGLFDN++++ I+ +AL+WE                +W  G    L   ++  +  LA  L  +ARE SLD+++DSPFALLAK+NDIMW GGMPDD TV+   V+ ++
Sbjct:    1 EVKRRRVADVPIREVLDSKHAYRWVNPVISEDATIRNAIPTVIEGGLSGMMVIEAPKNPSEKDKNNHTESPRRVVGLLTSRDLLRMMAAGFKDENITDEEIVNKVIGDYMTPMSQVIYGRPTETIGMCRSLMSKLGIKCLPILSKEGKVEGLITARDMNDYGLSASDRGGKKSYLNDVSERVGLSSDTSMAEPPLYMNAHLALEQKPLSVNMGVDELPHPYKTHDG-VGHNRRDHGPQDLATDLDLSEDAYFCTRVHLEDENDQFLRDVTYFGVADGVGSWRQYGVDPRLFSHKLMEECENILLEACHRDKDIGGGKFRRVIPPA--DIIAQAYERVKAE--NIIGSSTACVALFDCIRHQLHFSNLGDSGIIVLRHIDSDIAGTLKRDRITPRAERSSDLRVAFISQQQLFSFNHPYQVGWTGEELSTDEHTSFKTARDSCTTSIHLRRGDIIIMATDGLFDNVDIDDITKIALKWEQGVGLIRGGDIAAREQRWAMG--NSLTILSSEKVGSLASELCEKARENSLDSSKDSPFALLAKDNDIMWSGGMPDDCTVIVAHVVGRS 559