EsuBft1000_3 (polypeptide) Ectocarpus subulatus male Bft15b

Query:    1 MASIPDNRKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDAGMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVETLKELYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKDGDKEPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGSGXXXXXXGLPDMTNMTAAEKKRVKAKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQATPPSPGQPAASGAPADGSSTXXXXXXXXXXXXLVARVLAEEAEWLLGTGGLAGAVAELVRLAEDAETGSLGARVCAAKALSLTTAEEGREQAVRIVREGLGGRGVTVPGCATAVEAVRGIVGEDGSAAVDALREVCAKTFPNAEVFKSFSAQEVVASRG 981
            MASIPDNRKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDR+QRADERYPHSELLLYKNLALSDAGM QEALDHLEECSDKVMDKLGWT KKGELLL LGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVETL +LYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFE+QGAP SV AGGDADGGEEKLGRPSPVV+DAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKDGDKEPEETLAW LFLRAQLEE TGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGS       GLPDMTNMTAAEKKRVKAKARRDA XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAM+RGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQATPPSPGQPAAS APADGSST       XXXX LVARVLAEEAE LLGTGGLAGAVAELVRLAEDAETGSLGARVCAAKALSLT AE+GREQAVRIVREGL GRGVTVPGCA AVEAVRG+VGEDGSAAV+ALREVC  TFPNAEVFKS SAQEVVAS G
Sbjct:    1 MASIPDNRKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRYQRADERYPHSELLLYKNLALSDAGMTQEALDHLEECSDKVMDKLGWTKKKGELLLALGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVETLTKLYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFEKQGAPTSVAAGGDADGGEEKLGRPSPVVTDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKDGDKEPEETLAWTLFLRAQLEERTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGSAGGGGAAGLPDMTNMTAAEKKRVKAKARRDAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMRRGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQATPPSPGQPAASCAPADGSSTPSPTTGPXXXXPLVARVLAEEAEGLLGTGGLAGAVAELVRLAEDAETGSLGARVCAAKALSLTAAEQGREQAVRIVREGLDGRGVTVPGCANAVEAVRGVVGEDGSAAVEALREVCGNTFPNAEVFKSSSAQEVVASSG 981          

Query:    1 MASIPDNRKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDAGMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVETLKELYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKDGDKEPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGSGXXXXXXGLPDMTNMTAAEKKRVKAKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP-PVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQA-TPPSPGQPAASGAPADGSSTXXXXXXXXXXXXLVARVLAEEAEWLLGTGGLAGAVAELVRLAEDAETGSLGARVCAAKALSLTTAEEGREQAVRIVREGLGGRGVTVPGCATAVEAVRGIVGEDGSAAVDALREVCAKTFPNAEVF 968
            M++  DNR LPKREAD+FKSI+K YE K YKKG+KAA+ VLKKFP HGETLAMKGL L+ LGKK+EAHD V+RGLRADL+SHVCWHV+GL+HRS++NY EA+K + NAL+ EPE+L IL+DLA  Q+Q+RE++G ++TR ++L LKSN +Q+W AYAVA+ +AG  ET +  ID+F+KT+           Y  SELLLY+N  L D+G  ++AL HL+     +MD  GWT+ KG+LL+  GR  DA  ++RELL+RG E+Y  HRG        P K  +E L +    L          L   +  TL  LYR L+E++  S AA RIPL FLEG+EL + L+ Y++  LRKGVPSLG DL S+F                   E  GR   V +D  DL  HP+   V  +   FV +LR   R       +D   EP  TL W +FL++ L +  G L EA    EEC AL P +++  Q K RVL+KMGA   AA+A+D+AR LD +DRY+N+K TKY+LRA ++P+AE+TIA+FTRHEGDP +NLFEMQCSWFELEWAE+ +R GK GL +KKA AV  HF+DFVEDQ DFHTYCMRK+TLR+Y+ ML+M D +     +RRA+AL+++AYL + ++   +         PD + M+AA+KK+          XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX                         P D DP G  L EK+PLPEAAR+  +LS  A  +VET  L FDVA++RGK+LLA RAV +GRA+ P +P +L RT++LYH+  A   P P + AA                          VLA+E   LL    LA   A +   A  A T  L  R+ A +  +L + E+    A  +V  GL   GV+   C  A+  +RG    +  A  DA + +CA  FP A  F
Sbjct:    1 MSNATDNRTLPKREADVFKSIVKCYEGKLYKKGVKAADQVLKKFPNHGETLAMKGLILSCLGKKDEAHDLVKRGLRADLKSHVCWHVFGLIHRSDKNYMEAVKCFHNALRLEPESLTILRDLAGAQVQLRELRGHMDTRLRILTLKSNYKQHWMAYAVASDLAGERETAIDVIDSFLKTMPP-----GSINYEDSELLLYRNYILCDSGKAEDALVHLDTIRKDIMDIGGWTMCKGQLLMATGRPADAADLFRELLERGSENYAVHRGAG------PLKMFQERLLVTLNML---------MLTPEQKSTLIGLYRELQEKYPKSAAARRIPLAFLEGDELMAPLEEYVQSNLRKGVPSLGNDLCSLFTI-----------------EVEGRRR-VATDPKDLMGHPLLAAVCQMCDRFVTALRCASRI------RD---EPPSTLMWTMFLKSFLLKKQGLLDEALQVAEECIALSPEVIEMHQCKARVLKKMGAYGLAADAMDAARQLDLSDRYINNKTTKYMLRADRVPEAERTIALFTRHEGDPMYNLFEMQCSWFELEWAESHMRQGKLGLCLKKAFAVEHHFQDFVEDQVDFHTYCMRKMTLRAYVAMLKMEDTIYGHHFFRRAAALVIKAYLTIFEQPQAAASSAE----PDYSGMSAADKKKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXANGEKNDDDEETGKPKKRGRHGQEIPPDDDPNGQKLAEKEPLPEAARIAGILSRQAAGHVETWALVFDVAIRRGKWLLALRAVCKGRAIAPSDPGMLRRTVELYHKLDALAEPLPERAAA--------------------------VLADERADLLDGMSLADYAAAIQARAAMAAT--LQGRLEATRTAALLSPEDKGAAAAALVAGGLECGGVSAAACREALAVLRGEF--EAQAQADAFQVLCATKFPQATAF 889          

Query:    4 IPDNRKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDAGMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALK-LRACELPSGALRAAGKLGEAEVETLKELYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQG-APPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKDGDKEPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGS-------GXXXXXXGLPDMTNMTAAEKKRVKAKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQATPPSPGQPAASGAPADGSSTXXXXXXXXXXXXLVARVLAEEAEWLLGTGGLAGAVAELVRLAEDAETGSLGARVCAAKALSLTTAEEGREQAVRIVREGLGGRGVTVPGCATAVEAVRGIVGEDGSAAVDALREVCAKTFPNA 965
            +PDNR LP REA +F+SI++ YE+K+YK+ LKAA+ VLK+FP HGETLAM+GLTLNAL KKEEA+DHV+RGLR DL+SHVCWHVYGLL+RS+RNY EAIK YLNALK + ENLQIL+DL+ LQ+Q+++  GF+ETRRK+L LKSN + +W +YAVAN + G  +T V+ ID+++ T + +    A  R+  SEL+L++N A+ + G  ++AL HLEE   KV+D   +  +K ELLL LGRH++A  ++  LLD   E+Y +HRG Q A+L+L  ++    L+ +++  LPS  +     L + + + L + Y GL E+F  S A  RIPL  L+ E+ +  L  Y+ + LRKG P+LG DL ++      A P   +                +  D FD+R   +   ++ +    + SL+     P  EGE +        L +A++L+ QL E    L+EA    EEC    PT +DF  RKGR+L+KMG    AAE +D AR +D ADRY+N+KATKYLLRA ++ +AE TIA+FTRHEGDPQ NL+EMQCSW+ELEWAE+Q+R  K GLA+KK  AV  HFEDF+EDQFDFHTYC+RK TLR+Y+ +LRM    +S   ++RA+  ++  YLRLHD+ P S       G       +P+    T +E                             XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX         P D DP G  LL + PL EA++  ++L+  A   ++TH+L++DV+ +RGK L++ RA+++G  + PR+PEL  R +  + +  A+  +P     +G     +S              VA  + E A++  G                  + G+L  R  AA A +   + +  E A+ +VR GL GRGV+V  C  A++AV+   G++ +     +RE+    FP+A
Sbjct:    5 LPDNRTLPNREAVVFRSIVRYYEQKQYKRALKAADQVLKRFPQHGETLAMRGLTLNALDKKEEAYDHVKRGLRNDLKSHVCWHVYGLLYRSDRNYGEAIKCYLNALKWDSENLQILRDLSLLQVQLQDYDGFIETRRKILTLKSNNKMHWISYAVANLLGGRCDTAVRVIDSYLAT-ETESSADASSRFEDSELVLFRNQAVCEGGNFEDALRHLEEVQHKVVDTRSYHAQKAELLLRLGRHQEAASVFHVLLDANCENYEYHRGFQAALLQLDAEKLAVVLETMKSTALPSSEMM----LDDPQRDALAQAYDGLLEKFPRSAAVRRIPLQILKEEDAQPRLRDYVAQGLRKGKPNLGADLRTLLRMPDPARPGYFS----------------IAKDPFDVRTLTLFDFLLQVADESIASLKQDDALPDGEGEANPS-----VLLFAMYLKVQLLEAANRLEEALALAEECIEHTPTAIDFYLRKGRLLKKMGQFDAAAEVIDFARRIDLADRYVNNKATKYLLRADRVEQAESTIALFTRHEGDPQFNLYEMQCSWYELEWAESQLRQRKYGLALKKFFAVDKHFEDFMEDQFDFHTYCVRKGTLRAYVDLLRMASGSQSHAMFQRAARGIITTYLRLHDD-PSSVVAVQTNGTLGHDENVPNGAQQTPSE---------------PTEAAPQMTAAQRKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAETGRRKSKPADDDPYGEKLLSRSPLSEASKFCSILNLRAPHVIDTHILSYDVSARRGKSLMSLRALVKGFEVAPRDPELFKRIVD-FEDGIASGRTPLDETQAGIVTSMASRWRREG--------VADFVHEYADFACG------------------DLGNLAMRTAAAAATAKLDSSKAAE-ALGMVRGGLRGRGVSVASCRAALQAVKAFAGDEAAELEIEIREL----FPSA 901          

Query:    2 ASIPDNRKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDAGMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRG--DEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVETLKELYRGLRERFEGS-PAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVF----ERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKDGDK--------EPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGSGXXXXXXGLPDMTNMTAAEKKRVKAKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPR----NPELLLRTIQ--LYHEAQATPPSPGQPAASGAPADGSSTXXXXXXXXXXXXLVARVLAEEAEWLLGTGGLAGAVAELVRLAEDAETGS-LGARVCAAKALSLTTAEEGREQAVRIVREG-LGGRGVTVPGCATAVEAVRGIVGEDGSAAVDALREVCAKTFPNA 965
            ++IP  R LPK+E+DLFKSI K YE K+YKKGLKAA+ +LKK+P HGET AMKGL LN + +K EA+D V++ L  D++SHVCWHVYGLLHRS+  Y +AIKSY  A++ + +N+QIL+D++ LQ+Q+R+++GF +TR KLL LK N + NW AYAV+N +AG     V  IDA+ KT      + AD  Y  SEL+LY+NL LS+ G ++EAL+HL EC   V+DK+ W IK  EL L LGR E++  ++R+LL  G   E+Y+ H G QCA+L+L    C    KL AC++PS +L     L   + + L+E Y  L     G   AA RIPLTFL+GE+LR +L AY++R L +GVP+L  DLS+++     R    P++T                    D F +  HP  Q+V+ L    ++SLR+  RFP+   + D D         EP  +L W LFL  QL E  G  ++A   ++ C    PT  DF +R+ R+LRK G +  AA  +D+AR LD ADRY+N+K TKY+LRAG++  A  TIA+FTRHEGDPQ NLFEMQ  W E+E+ EA +R  K G+A+KK LAV  HF DF++DQFDFHTYC+RK+TLR+Y+ +L+M D ++S K + RA+   V+ YL + D    S         PD  +MT A++KR KAKAR+ AK       XXXXXXXXXX                                         PVD DPLG  LLE DP+ EA RLVA+L+  A  ++ T L+AFD A++R K LLA RA++ G          +PEL++R     + ++   TP +  Q     A                    V   +  E   LLG   +    A L + + D +T   L   + AAKALS        E AV ++ EG L    V+V  CA A+E +R  +    S   +A R VC   +P A
Sbjct:   37 SNIPPGRHLPKKESDLFKSIAKHYETKQYKKGLKAADQILKKYPDHGETQAMKGLVLNCVDRKSEAYDLVKKALHNDMKSHVCWHVYGLLHRSDHKYLDAIKSYKMAVRIDGDNMQILRDMSLLQVQMRDLEGFQKTRHKLLQLKPNQKMNWMAYAVSNQLAGCNPIAVTVIDAYSKTTDS---RTAD--YEESELMLYRNLLLSEDGKLEEALEHLTECEKYVVDKMAWRIKFAELTLLLGRFEESRALWRQLLVEGGAQENYSVHGGWQCALLELDAATCRRMRKLSACDVPSNSL---ADLTSPQRDLLEEAYISLLGDLGGRCRAAQRIPLTFLQGEKLRFALQAYLQRMLNRGVPALAADLSALYTTLDSRNPGTPTLTR-----------------CKDPFAVGQHPTFQVVLRLCTKILKSLRANERFPSNTCDDDADTTLSGETAIEPPTSLLWCLFLHVQLLEARGDYEDALTAVQLCIDHTPTAGDFYERRARLLRKSGNVKAAANEMDAARTLDLADRYINNKTTKYMLRAGRLKDAMSTIALFTRHEGDPQQNLFEMQVMWVEIEYGEAGLRDKKYGVALKKFLAVEKHFNDFIDDQFDFHTYCLRKMTLRAYVSILQMNDRIQSHKFFHRAAVGAVKCYLAVFDAPKTSDNSGAQS--PDYASMTPAQRKREKAKARKAAKKAADEKEXXXXXXXXXXETNNKDAKNKKKTSADR------------------------PVDEDPLGDKLLEADPMLEAKRLVAILTRFAPRHLSTQLVAFDTAIRRNKPLLALRALVMGGRCSGGGSFGHPELIVRLADFAVKYQGYNTPEAAEQQHLVPA--------------------VREAVDLEISALLGGMSVE---AYLSKYSGDVDTKRCLSKSLAAAKALSKIGKSTSVEAAVALIVEGGLDRMDVSVATCADALEFMRSEL--KASEQAEAWRGVCLAKYPRA 947          

Query:    8 RKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDA-GMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRGD-EDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAA----GKLGEAEVETLKELYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKDGDKEPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGSGXXXXXXGLPDMTNMTAAEKKRVKAKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQATPPSPGQPAASGAPADGSSTXXXXXXXXXXXXLVARVLAEEAEWLLGTGGLAGAVAELVRLAEDAETGSLGARVCAAKALSLTTAEEGREQAVRIVREGLGGRGVTVPGCATAVEAVRGIVGEDGSAAVDALREVCAKTFP 963
            R LPK+E+DLFKS++K YE K+YKKG+K+A+A+LKK+P HGETL MKGLTLN  GK++EAH+ V++GL  D+RSHVCWHVYGLLHRS+R+Y EAIK+Y  AL+ + ENLQIL+DL+ LQ+Q+R+V GF  TR  +L LK N + NW ++A+A H+  + +  V  ID ++ TL+ D  +     +  SEL LY+N  L++    + EAL+HLE C D VMD   W   K   LL +GR E+A  IY EL  RG  +DY  H G  C+VL++    C EAL+L+     +  +  +    GKL +A  E L ++     E    S A  RIPLT LEG+EL  SLD Y RR L KGVPSLG+DLS++F                   EK  R S  V+D  D++ HP+  M+++L   ++ +L S  +F ++  E++   +   TL WAL+LR+ L E  G   E     ++C    PT +D  + KGR+L   G ++ AA+A+D  R LDK DRY+N++ T+YLLRA +  +A   IA+FTRHEGDP+ NL++MQCSW+ELE A    R  + G ++KK +AV  HFEDF +DQFDFH+YC+RKVTLR+Y  +LR  ++L  Q  Y +A+  ++R YL LHD              PD + MTAAE+K+ KA A     XXXXXXXXXXXXXXXXXXXXXX                                     VD DP G+ LL+ DPL EA +  A+LS +A   V T +L +DVA++RGK L+A +A+++ RALEP N E+  RT+          P+P          D SS              V  VL +E+  LLG       V +    A++    SL  R+  AKAL  T A    E    I+  G+ GRGV+V  C  A++ +    GE  +   +   E+  K FP
Sbjct:   11 RPLPKKESDLFKSVVKHYETKQYKKGIKSADAILKKYPNHGETLCMKGLTLNCQGKRDEAHELVKKGLMNDMRSHVCWHVYGLLHRSDRSYNEAIKAYKQALRIDSENLQILRDLSLLQVQMRDVPGFGVTRHTILTLKPNQKINWLSFAMAKHLGDDLKGAVNVIDIYIGTLEKDSPELR-RGFETSELALYRNTILAEIPDNLAEALEHLESCKDVVMDIGSWFQLKASYLLRMGRFEEARNIYVELFKRGHGDDYRLHSGYMCSVLEVDRSLCSEALELKGTATLATMVPLSCDQKGKLLDAYREELGDIIGPGAEI--KSQAYRRIPLTLLEGDELIKSLDKYCRRGLSKGVPSLGSDLSALFLI-----------------EKKERYS-TVTDPVDVKLHPIFAMIIELVDGYISTLESGSKFSSSAFEEE---QSPSTLLWALYLRSFLHELCGEYSEGITVADKCIEHTPTAVDVYELKGRLLAAAGDISSAADALDQGRELDKQDRYINNRTTEYLLRANREDEARSRIALFTRHEGDPERNLYDMQCSWYELEVASCLARKEEWGKSLKKYMAVVKHFEDFHDDQFDFHSYCIRKVTLRAYADVLRFENELWGQPYYGKAAEGVIRNYLHLHDHPEARTKAAGEE--PDYSKMTAAERKKAKAIAXXXXXXXXXXXXXXXXXXXXXXXXXXXNNPDNGNNKKGKGKSAQQAV-----------------VDEDPDGVALLKLDPLEEAKKFSAILSTNAPTRVSTWVLQYDVAIRRGKQLMALQALLKARALEPENSEVFKRTVDFVQR-----PAP----------DVSSNAT-----------VKDVLKQESSNLLGEKSPTQFVMDAAARAKENMLTSLPMRIAVAKALISTKAGSVTEATSLIIDGGIDGRGVSVDSCCEALKCLCSF-GEGATKGKEKWLELAKKRFP 902          

Query:    2 ASIPDNRKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDAGMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVETLKELYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGE----KDGDKEPEE--------------TLAWALFLRAQLEETTGFLQEAYDTLEECAAL----QPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQI-RAGKPG--------LAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAY---LRLHDERPGSGXXXXXXGLPDMTNMTAAEKKRVKAKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQATPPSPGQPAASGAPADGSSTXXXXXXXXXXXXLVARVLAEEAEWLLGTG-GLAGAVAELVRLAEDAETGSLGARVCAAKALSLTTAEEGR-EQAVRIVREGLGG---RGVTVPGCATAVEAVRGIVGED---GSAAVDALREVCAKTFPNAEVF 968
            A+IPDNRKL K+E DLF+SI+K YE K+YKKGLKAA+++L+K+P+HGET AMKGL LN + +KEEA++ V++GLR D+RSHVCWHV+GLLHRS+RN+ EAIK YLNAL+ +  N+QILKDLA LQ+Q+R++ GFVETRRK+L     L+ +W  + +ANH++G+    +  ID+F+ TL     ++ +  +   EL+LYK + L  AG  +EAL  LE     VMD L W  ++  LLL   + E A + YR LL    E+Y +H G QCA+L+                LPS A   AG L EA  + L   Y  L      S    ++PLTFLEGE  ++ +DAYMRR+L +G+P+LG++L+++F  +          D + G     +      DA+DLR +   Q+V  L   ++E+L  TG FP+        ++G   P                TL WA +L+ QL E+ G + EA   LEEC A         LDFLQR+ R+L+K G +T AA  +D AR LD +DRY+N++ TKYLLRAGQ+  A+  IA+F +HEGDPQ  L +MQC W+ELEWA A    A KP          A+K+ +AV  HF DFVEDQFDFH YC+RK+TLR+Y+ +LR+ D L +   Y  A+  ++  Y   L +  E  G        G      MTAAEKK+ KA       XXXXXXXXXXXXXXXX      XXXXXXXXX                            VD DP G+ L+E++PL E  R+VA L+ HAG  VETH+LA+DVA KRGK LLA +A+IR  AL P +P++  RT+  +          G+    G   +  ++              A V+  E + LLG    L   V E V  A      SL   + AA+ ++L   E G  E A+ ++RE L     RG+TV G    VE    +VG++   GSA V  ++++C + FP+A  F
Sbjct:    7 AAIPDNRKLSKKEHDLFRSIVKFYETKQYKKGLKAADSILRKYPSHGETQAMKGLILNCMERKEEAYELVKQGLRNDVRSHVCWHVFGLLHRSDRNHGEAIKCYLNALRIDTSNMQILKDLANLQVQMRDLDGFVETRRKILSENCKLKVHWIGFVLANHLSGDLGMALSVIDSFLGTL-----EKRERGFEEGELVLYKAMLLEQAGRKEEALSWLESQKSFVMDGLAWRTRRAHLLLASEQFEKALEAYRALLAENSENYEYHLGWQCALLRRDSSNSAAMFAQPQASLPSSA---AGDLDEAASQQLLAAYGELARAEPHSLVCEKVPLTFLEGEAFKTRVDAYMRRHLARGLPALGSELAALFRTE----------DPENGRRIQAK------DAYDLRKNKRFQIVQLLVDEYIETLAMTGAFPSPTTSVAPCQNGSHPPSSSPSPSTSQAFDVTTTLLWAKYLKVQLLESAGEIPEALKLLEECLAACGEDTGAKLDFLQRRARLLKKGGRVTDAAVVMDEARQLDLSDRYLNNQTTKYLLRAGQVEAAQNVIALFAKHEGDPQVYLTDMQCMWYELEWAHATFSEATKPSGGGRALIAKALKRYVAVEKHFADFVEDQFDFHNYCVRKMTLRAYVDVLRLEDGLLAHPYYLAAARGMLDCYMAVLEMPKEEEG------VEGKDAYAGMTAAEKKKEKAXXXXXXXXXXXXXXXXXXXXXXXRVANAGXXXXXXXXXEEGKGKSTTNKKGGDGGKGV--------VDEDPEGMKLIEREPLTEMKRVVAYLTRHAGKVVETHMLAYDVACKRGKALLALQALIRAHALRPMHPDVFRRTVHFWTGM-------GESGGEGGKQEWIASLHPTS---------AAVIDAEKQRLLGEKKNLGSYVTEYVEKARA--WSSLPHVLAAARGVALAKTEPGATEVAIGLIREELQKGQCRGLTVKGLRQVVE----VVGKELDAGSATVAEMKKLCHQYFPDALEF 955          

Query:   25 YERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDAGMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALK---LRACELPSGALRAAGKLGEAEVETLKELYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTG-RFPTAEGEKDGDKEPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGS--GXXXXXXGLPDMTNMTAAEKKRVKAKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPRNPELLLRTI 814
            YE+K+Y++ LK+A+ VLKKFP HGETLAM+GLTLNAL KKEEA+DHV+RGLR DLRSHVCWHVYGLL+RS+RNYAEAIK YLNALK + +NLQIL+DL+ LQ+Q+++  GFVETRRK+L LKSN + +W +YAV N + G  E+    ++ ++ T + D  +     Y  SEL+L++N A++++G + EAL  L+    KV+D   +   KG  LL LGRH DA  +YRE L+   E+Y +HRG Q A+L L      ++L    L+   LPS  L     L  A+V TL E Y  L E +  SPA  RI L FL   E +  L AY+   LRKG P+LGTDL ++       P  T          KLG  + +  D  D+   P+ Q  + +    + S R  G   P   G      E    L WA+FL+ QL E  G L EA    EEC    PT +D   RKGR+L+K+G    AAE VD AR +D ADRY+N+KATKYLLRA ++ +AE TIA+FTRHEGDPQ+NLFEMQCSW+ELEWAE+Q R  K GLA+KK  AV  HFEDF+EDQFDFHTYC+RK TLR+Y+ +LRM   ++S + ++R +  ++  YL L+D+ P S         G  +  + TAA+     AK      XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX     DP+G  L  +DPL EAA+   LL+  A   ++TH+L++DV ++RGK L+A RA+++G  + P++ EL  R +
Sbjct:   16 YEQKQYRRALKSADQVLKKFPQHGETLAMRGLTLNALDKKEEAYDHVKRGLRNDLRSHVCWHVYGLLYRSDRNYAEAIKCYLNALKWDRDNLQILRDLSLLQVQMQDYDGFVETRRKILTLKSNNKMHWISYAVGNLLGGRCESAAHIVNTYLNT-EVDTGEGGGPGYEDSELVLFRNQAIAESGKLDEALADLDAIKTKVLDMRAYLSMKGTYLLKLGRHGDAAAVYREALELNAENYDYHRGYQAALLTLEGDALADSLPGGALKFTALPSSELA----LDAAQVATLVEAYAKLTEAYPRSPAVKRIQLAFLPEAERQERLRAYIVNALRKGKPNLGTDLRTMLRV----PHPT----------KLGFLA-LAKDPLDVATLPLTQFFLGVADECIASTRENGGALPAWAGAPPTGGESPSALLWAMFLKVQLLEAMGMLAEALALCEECITHTPTAIDLYMRKGRLLKKLGDTQEAAEVVDFARKIDLADRYINNKATKYLLRADRVEQAEGTIALFTRHEGDPQYNLFEMQCSWYELEWAESQQRQRKYGLALKKFFAVDKHFEDFMEDQFDFHTYCLRKGTLRAYVNLLRMASGVQSHEFFQRTAKGIITTYLALYDD-PASMVAVEPKTNGAAENDDATAADTSDKPAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----DPVGAKLAARDPLEEAAKFCKLLNLRAAGAIDTHVLSYDVCVRRGKPLMALRALVKGYEIAPKDAELFRRIV 786          

Query:    8 RKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDA-GMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRG-DEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVETLKELYRG-LRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKDGDKEPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGSGXXXXXXGLPDMTNMTAAEKKRVKAKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQATPPSPGQPAASGAPADGSSTXXXXXXXXXXXXLVARVLAEEAEWLLGTGGLAGAVAELVRLAEDAETGSLGARVCAAKALSLTTAEEGREQAVRIVREGLGGRGVTVPGCATAVEAVRGIVGEDGSAAVDALREVCAKTFPNAEVFKSFS 972
            R LPK+EADLFKS++K YE K+YKK +K+A+ +LK+FP HGETL MKGLTLN++ K+EEAH  V++GL  D+RSHVCWHV+GLLHRS+RNY EAIK+Y  AL+ +PENLQIL+DL+ LQIQ+R++KGFV TR  +L LK N + NW A+A+A H+ G+    V  ID ++ TL  +     ++ +  SEL +Y+N  L++    + EAL+HL+ C + ++D   W + K    L LG++E+A + +  +  RG  EDY  H G  CA+LKL    C +ALKLR     +  +     L + E +TL + Y G L E    S A  RIPL+ L G++L+ ++ +Y R+ L KGVPSLG+DLS++F                   EK GR   +  D  D+R H    M++ L   ++ SL S  +F  A+GE++   E   T+ WA +LRA L E  G   +     ++C    PT +D  + K R+L+  G    AA+ +D  R LDK DRY+N++ TKY+L+A +   A + IA+FTRHEG+P+ NL++MQC+W+ELE A    R G+ G ++KK +A+  HFEDF EDQFDFH+YC+RKVTLR+Y  +LR  D+L  Q+ Y +A+  ++R Y+ L+D     G        PD + MTAA++K+ KA A     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX                        VD DP G  LL++DPL EA +  A LS HA   + T +  +DVA++R K L+A +A+ + +A++  + EL  R +    + ++   +                            ++  VLA E   LL    L+  V+E    A+      L  RV  AK L  T     +E +  I+  GL GR V+V  C  A+  +  +    GS A DA  E  AK      +  +FS
Sbjct:   14 RPLPKKEADLFKSVVKHYECKQYKKVIKSADTILKRFPNHGETLCMKGLTLNSMSKREEAHALVKQGLMKDMRSHVCWHVFGLLHRSDRNYNEAIKAYKQALRIDPENLQILRDLSLLQIQMRDIKGFVVTRNTILTLKPNQKINWLAFALAKHLNGDLRGAVSVIDIYLGTLN-EGSLELEKGFESSELAMYRNKILAEIPDNLDEALNHLDACKNVIVDMGAWLMSKATFQLKLGKYEEALETFVAMFQRGLTEDYRVHTGYMCALLKLNADDCADALKLRG----TNTVATMRPLTDDERKTLIDAYTGDLLESHPRSRAVRRIPLSILVGDKLQDAVASYCRKGLTKGVPSLGSDLSAMFL-----------------VEKDGR-YVLADDPADIRAHSNFSMLVGLVDGYISSLLSHSKFSDADGEEE---ESPSTVLWAWYLRAFLHELAGEYMDGIALADKCIEHTPTAVDVYELKARLLQAAGDKGAAADCLDKGRELDKQDRYINNQTTKYMLQADRDSVARERIALFTRHEGNPEQNLYDMQCTWYELELAACMARKGQWGRSLKKYMAIDKHFEDFHEDQFDFHSYCIRKVTLRAYSDVLRFEDNLWGQQYYCQAAEGIIRNYVFLYDNPSAVGVEEE----PDYSEMTAAQRKKAKAIAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPSV---------------------VDEDPDGEELLKRDPLEEAKKYSATLSKHAPNRISTWMGQYDVAIRRKKVLMALQALFKAKAIDKESNELFTRIVDFVQKVESEKEA--------------------------NPIIKEVLASETTTLLEGKSLSDFVSEAASRAKSDALTDLPKRVAVAKGLIATNVGTVKEASSLIIDGGLEGRKVSVDTCRDALRCLTFL----GSDAEDAKTEWVAKVKEKFPLMTNFS 900          

Query:    7 NRKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDAGMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVE-TLKELYRGLRERFEG-SPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKD-GDKEPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGSGXXXXXXGLPDMTNMTAAEKKRVK---AKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALE 803
            +++LP +E+ LF+SI+K YE K+YKKGLKAA+A+LKK P HGETLAMKGLTLN +G+K+EA++ V+ GLR DLRSHVCWHV+GLL+RS+RNYAEAIK Y NA++ +PENLQIL+DL  LQ+Q+R++KGF ETRR +L LK N + NW  +A+A+H+ GN +  +  I+ +  TL+G+     +  Y  SE+ LY+N  + +AG I++AL HLEE  D++ D L W  KKG+ LL L R++DA   + ELL+   ++Y FHRGLQCAVLK          + +   LPS  +  + +   A++E  L + Y   +      S  + R PL F  G E     D Y+++ L K VPSLG DL  ++              AD  + K+                     + +L   +++SL +  + P  +G+        E+ L W  +L AQ  +  G   +A + +E+C   +P++LDF QRK R+L+ MG L +AA+ +   R LD ADRY+N+KAT+YLL A ++ +A+ TIA+FTRHEGDPQ NLFEMQC W+E+E  ++Q+R  K GLA+K+  AV  HF DF+EDQFDFHTYC+RK+TLR+Y+ MLR+ D++ S+  +  A+   +  Y  L D+     XXXXXX      NM+AAEKK+     AKAR+                                                             P D DPLG  L EK  L EA R V++L  +A   V+TH+ AFD+A+++ K+LL  +A+++ + +E
Sbjct:    5 SKQLPAKESALFRSIVKCYEIKQYKKGLKAADAILKKHPEHGETLAMKGLTLNCMGRKDEAYELVKSGLRHDLRSHVCWHVFGLLYRSDRNYAEAIKCYRNAIRIDPENLQILRDLYLLQVQMRDLKGFAETRRTMLTLKPNNRNNWIGFAIAHHLVGNFQMAIDIIEKYFSTLEGEH----EANYEDSEIHLYQNQLIEEAGDIEKALKHLEENKDQITDTLFWRQKKGQFLLQLERYDDARAAFEELLEINFDNYEFHRGLQCAVLKRKDLFVARPTQKKT-PLPSEVVDFSKETNGAQLEKALADFYTEKKTTIGAESLISLRFPLDFTRGAEFEKYADVYLKKQLNKNVPSLGADLKPLY--------------ADKDKTKV---------------------LEELILGYLKSLEA--KKPLDQGDNSLAANATEKVLLWTNYLAAQHYDRLGNHAKAMEYIEKCIKQEPSLLDFFQRKARILKHMGDLNQAADVMVEGRKLDLADRYINNKATEYLLHADRVEEADATIALFTRHEGDPQQNLFEMQCMWYEIECGKSQLRQQKYGLALKRFFAVEKHFNDFIEDQFDFHTYCIRKMTLRAYIQMLRLCDEIYSRPFFVEAAHGAIACYEALADKEDKEXXXXXXXXXXXX-NMSAAEKKKXXXXXAKARK---------------------AEFKRKEEEELNAKLHKEAEEKEREAAKNGKPKANAGPTRPKDDDPLGEKLAEKPALEEAWRFVSILQQYASEDVKTHVAAFDIALRKKKFLLCLQALLKAQTVE 743          

Query:   10 LPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDAGMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVETLKELYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMD-LTKSFVESLRSTGRFPTAEGEKDGDKEPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGSGXXXXXXGLPDMTNMTAAEKKRVKAKARR-DAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLE-KDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQATPPSPGQPAASGAPADGSSTXXXXXXXXXXXXLVARVLAEEAEWLLGTGGLAGAVAELVRLAEDAETGSLGARVCAAKALSLTTAEEGREQAVRIVRE 920
            LP +E +LFK ++K YE K+YKKGLKAA+ VLKKFP HGETLAMKGLTLN L +KEEA+D+VRRGL+ DL+SHVCWHVYGLL+R++RNY EA K Y NALKH+P N QIL+DLA LQ+Q+R+  GFVETRR+LL  K N + NW A+A+A H++G     V+ I A+ KT++        ERY HSE+LLYK + + +AG  ++AL  L+E SD+++DKL    ++  LLL L R+ +AEK YR LL    ++Y ++RGL            E AL L+A         +AG   + +V  LK LY+ L ERF  S A  RIPL F+EGE+ R ++  Y+  +LRKGVPSL +DL  ++                                    N P +  +MD + K F  SLR  GRFP        D EP  TL W LFL AQ  +       A + +EE     PT+ D    K R+LR  G    AA   + AR LD ADRY+N++A K  L A Q+  AE+T A+FT+ +G+  ++LF+MQC W+E+   ++ +R    G A+KK LA+  H+ D +EDQFDFHTYC+RK+TLR+Y+ MLRM D L S K + + +A  +R Y+ L D +P  G      G    + ++A E+K+++AK R+ +AK         XXXXXXXXXXXXXXXXXX                               P DPDP G  L + +DPL E+ + + LL  HA   +ETHLLAF++ +++ K LLA +AV R  +++  +P++    + L+H    T P+P   +A                      LV RV+AEE + +    G +  + E         +GSL  R  AA+ + L       E AV IV E
Sbjct:    5 LPPKENNLFKLVVKSYETKQYKKGLKAADQVLKKFPEHGETLAMKGLTLNCLERKEEAYDYVRRGLKNDLKSHVCWHVYGLLYRADRNYREAAKCYRNALKHDPGNNQILRDLANLQVQLRDTAGFVETRRELLTTKPNNKNNWLAFAIAQHLSGRQHVAVEIITAYEKTVE---EYLDSERYEHSEMLLYKAMLMEEAGQFEQALRQLKENSDQIVDKLSIREQRAALLLKLNRNAEAEKEYRYLLAINSDNYNYYRGL------------EAALGLQAS--------SAGTWDDNQVAKLKTLYKELLERFPRSAAVKRIPLDFIEGEDFRKAISQYLPAFLRKGVPSLYSDLKPLY------------------------------------NQPGKAAIMDDVFKRFETSLREEGRFPAESSSSSTDPEPPTTLLWTLFLLAQHYDRRRLYDVALEKVEEAIKHTPTVPDLYLVKARILRHGGDAPAAAALAEEARSLDLADRYLNNEAVKRFLGADQVEDAERTAALFTK-DGEQHNSLFDMQCMWYEVASGDSHLRQSAYGKALKKYLAIEKHYADMIEDQFDFHTYCLRKMTLRAYIKMLRMEDHLHSFKFFCKGAAGAIRTYIALFD-KPAQGDNDDADGAN--SGLSALERKKLRAKQRKAEAKAKKAEETKRXXXXXXXXXXXXXXXXXXGGKKPKAEAVK--------------------PADPDPHGDKLAQVEDPLSESVQYLQLLQQHAAQAIETHLLAFELYIRKKKLLLALQAVKRLVSIDVTHPDVHRSLVTLFHTVD-TSPAPDSESAE---------------------LVHRVIAEERKEITALAGQS--LQEYNEAFLKEHSGSLLHRAAAAEVVVLLDCSRTAE-AVGIVEE 810          

Query:  217 MASIPDNRKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDAGMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVETLKELYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKDGDKEPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGSGXXXXXXGLPDMTNMTAAEKKRVKAKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQATPPSPGQPAASGAPADGSSTXXXXXXXXXXXXLVARVLAEEAEWLLGTGGLAGAVAELVRLAEDAETGSLGARVCAAKALSLTTAEEGREQAVRIVREGLGGRGVTVPGCATAVEAVRGIVGEDGSAAVDALREVCAKTFPNAEVFKSFSAQEVVASRG 3159
            MASIPDNRKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDR+QRADERYPHSELLLYKNLALSDAGM QEALDHLEECSDKVMDKLGWT KKGELLL LGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVETL +LYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFE+QGAP SV AGGDADGGEEKLGRPSPVV+DAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKDGDKEPEETLAW LFLRAQLEE TGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGS       GLPDMTNMTAAEKKRVKAKARRDA XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAM+RGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQATPPSPGQPAAS APADGSST       XXXX LVARVLAEEAE LLGTGGLAGAVAELVRLAEDAETGSLGARVCAAKALSLT AE+GREQAVRIVREGL GRGVTVPGCA AVEAVRG+VGEDGSAAV+ALREVC  TFPNAEVFKS SAQEVVAS G
Sbjct:    1 MASIPDNRKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRYQRADERYPHSELLLYKNLALSDAGMTQEALDHLEECSDKVMDKLGWTKKKGELLLALGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVETLTKLYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFEKQGAPTSVAAGGDADGGEEKLGRPSPVVTDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKDGDKEPEETLAWTLFLRAQLEERTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGSAGGGGAAGLPDMTNMTAAEKKRVKAKARRDAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMRRGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQATPPSPGQPAASCAPADGSSTPSPTTGPXXXXPLVARVLAEEAEGLLGTGGLAGAVAELVRLAEDAETGSLGARVCAAKALSLTAAEQGREQAVRIVREGLDGRGVTVPGCANAVEAVRGVVGEDGSAAVEALREVCGNTFPNAEVFKSSSAQEVVASSG 981          

Query:  217 MASIPDNRKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDAGMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVETLKELYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKDGDKEPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGSGXXXXXXGLPDMTNMTAAEKKRVKAKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXP-PVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQA-TPPSPGQPAASGAPADGSSTXXXXXXXXXXXXLVARVLAEEAEWLLGTGGLAGAVAELVRLAEDAETGSLGARVCAAKALSLTTAEEGREQAVRIVREGLGGRGVTVPGCATAVEAVRGIVGEDGSAAVDALREVCAKTFPNAEVF 3120
            M++  DNR LPKREAD+FKSI+K YE K YKKG+KAA+ VLKKFP HGETLAMKGL L+ LGKK+EAHD V+RGLRADL+SHVCWHV+GL+HRS++NY EA+K + NAL+ EPE+L IL+DLA  Q+Q+RE++G ++TR ++L LKSN +Q+W AYAVA+ +AG  ET +  ID+F+KT+           Y  SELLLY+N  L D+G  ++AL HL+     +MD  GWT+ KG+LL+  GR  DA  ++RELL+RG E+Y  HRG        P K  +E L +    L          L   +  TL  LYR L+E++  S AA RIPL FLEG+EL + L+ Y++  LRKGVPSLG DL S+F                   E  GR   V +D  DL  HP+   V  +   FV +LR   R       +D   EP  TL W +FL++ L +  G L EA    EEC AL P +++  Q K RVL+KMGA   AA+A+D+AR LD +DRY+N+K TKY+LRA ++P+AE+TIA+FTRHEGDP +NLFEMQCSWFELEWAE+ +R GK GL +KKA AV  HF+DFVEDQ DFHTYCMRK+TLR+Y+ ML+M D +     +RRA+AL+++AYL + ++   +         PD + M+AA+KK+          XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX                         P D DP G  L EK+PLPEAAR+  +LS  A  +VET  L FDVA++RGK+LLA RAV +GRA+ P +P +L RT++LYH+  A   P P + AA                          VLA+E   LL    LA   A +   A  A T  L  R+ A +  +L + E+    A  +V  GL   GV+   C  A+  +RG    +  A  DA + +CA  FP A  F
Sbjct:    1 MSNATDNRTLPKREADVFKSIVKCYEGKLYKKGVKAADQVLKKFPNHGETLAMKGLILSCLGKKDEAHDLVKRGLRADLKSHVCWHVFGLIHRSDKNYMEAVKCFHNALRLEPESLTILRDLAGAQVQLRELRGHMDTRLRILTLKSNYKQHWMAYAVASDLAGERETAIDVIDSFLKTMPP-----GSINYEDSELLLYRNYILCDSGKAEDALVHLDTIRKDIMDIGGWTMCKGQLLMATGRPADAADLFRELLERGSENYAVHRGAG------PLKMFQERLLVTLNML---------MLTPEQKSTLIGLYRELQEKYPKSAAARRIPLAFLEGDELMAPLEEYVQSNLRKGVPSLGNDLCSLFTI-----------------EVEGRRR-VATDPKDLMGHPLLAAVCQMCDRFVTALRCASRI------RD---EPPSTLMWTMFLKSFLLKKQGLLDEALQVAEECIALSPEVIEMHQCKARVLKKMGAYGLAADAMDAARQLDLSDRYINNKTTKYMLRADRVPEAERTIALFTRHEGDPMYNLFEMQCSWFELEWAESHMRQGKLGLCLKKAFAVEHHFQDFVEDQVDFHTYCMRKMTLRAYVAMLKMEDTIYGHHFFRRAAALVIKAYLTIFEQPQAAASSAE----PDYSGMSAADKKKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXANGEKNDDDEETGKPKKRGRHGQEIPPDDDPNGQKLAEKEPLPEAARIAGILSRQAAGHVETWALVFDVAIRRGKWLLALRAVCKGRAIAPSDPGMLRRTVELYHKLDALAEPLPERAAA--------------------------VLADERADLLDGMSLADYAAAIQARAAMAAT--LQGRLEATRTAALLSPEDKGAAAAALVAGGLECGGVSAAACREALAVLRGEF--EAQAQADAFQVLCATKFPQATAF 889          

Query:  226 IPDNRKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDAGMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALK-LRACELPSGALRAAGKLGEAEVETLKELYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQG-APPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKDGDKEPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGS-------GXXXXXXGLPDMTNMTAAEKKRVKAKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQATPPSPGQPAASGAPADGSSTXXXXXXXXXXXXLVARVLAEEAEWLLGTGGLAGAVAELVRLAEDAETGSLGARVCAAKALSLTTAEEGREQAVRIVREGLGGRGVTVPGCATAVEAVRGIVGEDGSAAVDALREVCAKTFPNA 3111
            +PDNR LP REA +F+SI++ YE+K+YK+ LKAA+ VLK+FP HGETLAM+GLTLNAL KKEEA+DHV+RGLR DL+SHVCWHVYGLL+RS+RNY EAIK YLNALK + ENLQIL+DL+ LQ+Q+++  GF+ETRRK+L LKSN + +W +YAVAN + G  +T V+ ID+++ T + +    A  R+  SEL+L++N A+ + G  ++AL HLEE   KV+D   +  +K ELLL LGRH++A  ++  LLD   E+Y +HRG Q A+L+L  ++    L+ +++  LPS  +     L + + + L + Y GL E+F  S A  RIPL  L+ E+ +  L  Y+ + LRKG P+LG DL ++      A P   +                +  D FD+R   +   ++ +    + SL+     P  EGE +        L +A++L+ QL E    L+EA    EEC    PT +DF  RKGR+L+KMG    AAE +D AR +D ADRY+N+KATKYLLRA ++ +AE TIA+FTRHEGDPQ NL+EMQCSW+ELEWAE+Q+R  K GLA+KK  AV  HFEDF+EDQFDFHTYC+RK TLR+Y+ +LRM    +S   ++RA+  ++  YLRLHD+ P S       G       +P+    T +E                             XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX         P D DP G  LL + PL EA++  ++L+  A   ++TH+L++DV+ +RGK L++ RA+++G  + PR+PEL  R +  + +  A+  +P     +G     +S              VA  + E A++  G                  + G+L  R  AA A +   + +  E A+ +VR GL GRGV+V  C  A++AV+   G++ +     +RE+    FP+A
Sbjct:    5 LPDNRTLPNREAVVFRSIVRYYEQKQYKRALKAADQVLKRFPQHGETLAMRGLTLNALDKKEEAYDHVKRGLRNDLKSHVCWHVYGLLYRSDRNYGEAIKCYLNALKWDSENLQILRDLSLLQVQLQDYDGFIETRRKILTLKSNNKMHWISYAVANLLGGRCDTAVRVIDSYLAT-ETESSADASSRFEDSELVLFRNQAVCEGGNFEDALRHLEEVQHKVVDTRSYHAQKAELLLRLGRHQEAASVFHVLLDANCENYEYHRGFQAALLQLDAEKLAVVLETMKSTALPSSEMM----LDDPQRDALAQAYDGLLEKFPRSAAVRRIPLQILKEEDAQPRLRDYVAQGLRKGKPNLGADLRTLLRMPDPARPGYFS----------------IAKDPFDVRTLTLFDFLLQVADESIASLKQDDALPDGEGEANPS-----VLLFAMYLKVQLLEAANRLEEALALAEECIEHTPTAIDFYLRKGRLLKKMGQFDAAAEVIDFARRIDLADRYVNNKATKYLLRADRVEQAESTIALFTRHEGDPQFNLYEMQCSWYELEWAESQLRQRKYGLALKKFFAVDKHFEDFMEDQFDFHTYCVRKGTLRAYVDLLRMASGSQSHAMFQRAARGIITTYLRLHDD-PSSVVAVQTNGTLGHDENVPNGAQQTPSE---------------PTEAAPQMTAAQRKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAETGRRKSKPADDDPYGEKLLSRSPLSEASKFCSILNLRAPHVIDTHILSYDVSARRGKSLMSLRALVKGFEVAPRDPELFKRIVD-FEDGIASGRTPLDETQAGIVTSMASRWRREG--------VADFVHEYADFACG------------------DLGNLAMRTAAAAATAKLDSSKAAE-ALGMVRGGLRGRGVSVASCRAALQAVKAFAGDEAAELEIEIREL----FPSA 901          

Query:  220 ASIPDNRKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDAGMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRG--DEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVETLKELYRGLRERFEGS-PAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVF----ERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKDGDK--------EPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGSGXXXXXXGLPDMTNMTAAEKKRVKAKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPR----NPELLLRTIQ--LYHEAQATPPSPGQPAASGAPADGSSTXXXXXXXXXXXXLVARVLAEEAEWLLGTGGLAGAVAELVRLAEDAETGS-LGARVCAAKALSLTTAEEGREQAVRIVREG-LGGRGVTVPGCATAVEAVRGIVGEDGSAAVDALREVCAKTFPNA 3111
            ++IP  R LPK+E+DLFKSI K YE K+YKKGLKAA+ +LKK+P HGET AMKGL LN + +K EA+D V++ L  D++SHVCWHVYGLLHRS+  Y +AIKSY  A++ + +N+QIL+D++ LQ+Q+R+++GF +TR KLL LK N + NW AYAV+N +AG     V  IDA+ KT      + AD  Y  SEL+LY+NL LS+ G ++EAL+HL EC   V+DK+ W IK  EL L LGR E++  ++R+LL  G   E+Y+ H G QCA+L+L    C    KL AC++PS +L     L   + + L+E Y  L     G   AA RIPLTFL+GE+LR +L AY++R L +GVP+L  DLS+++     R    P++T                    D F +  HP  Q+V+ L    ++SLR+  RFP+   + D D         EP  +L W LFL  QL E  G  ++A   ++ C    PT  DF +R+ R+LRK G +  AA  +D+AR LD ADRY+N+K TKY+LRAG++  A  TIA+FTRHEGDPQ NLFEMQ  W E+E+ EA +R  K G+A+KK LAV  HF DF++DQFDFHTYC+RK+TLR+Y+ +L+M D ++S K + RA+   V+ YL + D    S         PD  +MT A++KR KAKAR+ AK       XXXXXXXXXX                                         PVD DPLG  LLE DP+ EA RLVA+L+  A  ++ T L+AFD A++R K LLA RA++ G          +PEL++R     + ++   TP +  Q     A                    V   +  E   LLG   +    A L + + D +T   L   + AAKALS        E AV ++ EG L    V+V  CA A+E +R  +    S   +A R VC   +P A
Sbjct:   37 SNIPPGRHLPKKESDLFKSIAKHYETKQYKKGLKAADQILKKYPDHGETQAMKGLVLNCVDRKSEAYDLVKKALHNDMKSHVCWHVYGLLHRSDHKYLDAIKSYKMAVRIDGDNMQILRDMSLLQVQMRDLEGFQKTRHKLLQLKPNQKMNWMAYAVSNQLAGCNPIAVTVIDAYSKTTDS---RTAD--YEESELMLYRNLLLSEDGKLEEALEHLTECEKYVVDKMAWRIKFAELTLLLGRFEESRALWRQLLVEGGAQENYSVHGGWQCALLELDAATCRRMRKLSACDVPSNSL---ADLTSPQRDLLEEAYISLLGDLGGRCRAAQRIPLTFLQGEKLRFALQAYLQRMLNRGVPALAADLSALYTTLDSRNPGTPTLTR-----------------CKDPFAVGQHPTFQVVLRLCTKILKSLRANERFPSNTCDDDADTTLSGETAIEPPTSLLWCLFLHVQLLEARGDYEDALTAVQLCIDHTPTAGDFYERRARLLRKSGNVKAAANEMDAARTLDLADRYINNKTTKYMLRAGRLKDAMSTIALFTRHEGDPQQNLFEMQVMWVEIEYGEAGLRDKKYGVALKKFLAVEKHFNDFIDDQFDFHTYCLRKMTLRAYVSILQMNDRIQSHKFFHRAAVGAVKCYLAVFDAPKTSDNSGAQS--PDYASMTPAQRKREKAKARKAAKKAADEKEXXXXXXXXXXETNNKDAKNKKKTSADR------------------------PVDEDPLGDKLLEADPMLEAKRLVAILTRFAPRHLSTQLVAFDTAIRRNKPLLALRALVMGGRCSGGGSFGHPELIVRLADFAVKYQGYNTPEAAEQQHLVPA--------------------VREAVDLEISALLGGMSVE---AYLSKYSGDVDTKRCLSKSLAAAKALSKIGKSTSVEAAVALIVEGGLDRMDVSVATCADALEFMRSEL--KASEQAEAWRGVCLAKYPRA 947          

Query:  238 RKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDA-GMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRGD-EDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAA----GKLGEAEVETLKELYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKDGDKEPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGSGXXXXXXGLPDMTNMTAAEKKRVKAKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQATPPSPGQPAASGAPADGSSTXXXXXXXXXXXXLVARVLAEEAEWLLGTGGLAGAVAELVRLAEDAETGSLGARVCAAKALSLTTAEEGREQAVRIVREGLGGRGVTVPGCATAVEAVRGIVGEDGSAAVDALREVCAKTFPNA 3111
            R LPK+E+DLFKS++K YE K+YKKG+K+A+A+LKK+P HGETL MKGLTLN  GK++EAH+ V++GL  D+RSHVCWHVYGLLHRS+R+Y EAIK+Y  AL+ + ENLQIL+DL+ LQ+Q+R+V GF  TR  +L LK N + NW ++A+A H+  + +  V  ID ++ TL+ D  +     +  SEL LY+N  L++    + EAL+HLE C D VMD   W   K   LL +GR E+A  IY EL  RG  +DY  H G  C+VL++    C EAL+L+     +  +  +    GKL +A  E L ++     E    S A  RIPLT LEG+EL  SLD Y RR L KGVPSLG+DLS++F                   EK  R S  V+D  D++ HP+  M+++L   ++ +L S  +F ++  E++   +   TL WAL+LR+ L E  G   E     ++C    PT +D  + KGR+L   G ++ AA+A+D  R LDK DRY+N++ T+YLLRA +  +A   IA+FTRHEGDP+ NL++MQCSW+ELE A    R  + G ++KK +AV  HFEDF +DQFDFH+YC+RKVTLR+Y  +LR  ++L  Q  Y +A+  ++R YL LHD              PD + MTAAE+K+ KA A     XXXXXXXXXXXXXXXXXXXXXX                                     VD DP G+ LL+ DPL EA +  A+LS +A   V T +L +DVA++RGK L+A +A+++ RALEP N E+  RT+          P+P          D SS              V  VL +E+  LLG       V +    A++    SL  R+  AKAL  T A    E    I+  G+ GRGV+V  C  A++ +    GE  +   +   E+  K FP A
Sbjct:   11 RPLPKKESDLFKSVVKHYETKQYKKGIKSADAILKKYPNHGETLCMKGLTLNCQGKRDEAHELVKKGLMNDMRSHVCWHVYGLLHRSDRSYNEAIKAYKQALRIDSENLQILRDLSLLQVQMRDVPGFGVTRHTILTLKPNQKINWLSFAMAKHLGDDLKGAVNVIDIYIGTLEKDSPELR-RGFETSELALYRNTILAEIPDNLAEALEHLESCKDVVMDIGSWFQLKASYLLRMGRFEEARNIYVELFKRGHGDDYRLHSGYMCSVLEVDRSLCSEALELKGTATLATMVPLSCDQKGKLLDAYREELGDIIGPGAEI--KSQAYRRIPLTLLEGDELIKSLDKYCRRGLSKGVPSLGSDLSALFLI-----------------EKKERYS-TVTDPVDVKLHPIFAMIIELVDGYISTLESGSKFSSSAFEEE---QSPSTLLWALYLRSFLHELCGEYSEGITVADKCIEHTPTAVDVYELKGRLLAAAGDISSAADALDQGRELDKQDRYINNRTTEYLLRANREDEARSRIALFTRHEGDPERNLYDMQCSWYELEVASCLARKEEWGKSLKKYMAVVKHFEDFHDDQFDFHSYCIRKVTLRAYADVLRFENELWGQPYYGKAAEGVIRNYLHLHDHPEARTKAAGEE--PDYSKMTAAERKKAKAIAXXXXXXXXXXXXXXXXXXXXXXXXXXXNNPDNGNNKKGKGKSAQQAV-----------------VDEDPDGVALLKLDPLEEAKKFSAILSTNAPTRVSTWVLQYDVAIRRGKQLMALQALLKARALEPENSEVFKRTVDFVQR-----PAP----------DVSSNAT-----------VKDVLKQESSNLLGEKSPTQFVMDAAARAKENMLTSLPMRIAVAKALISTKAGSVTEATSLIIDGGIDGRGVSVDSCCEALKCLCSF-GEGATKGKEKWLELAKKRFPFA 904          

Query:  220 ASIPDNRKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDAGMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVETLKELYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGE----KDGDKEPEE--------------TLAWALFLRAQLEETTGFLQEAYDTLEECAAL----QPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQI-RAGKPG--------LAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAY---LRLHDERPGSGXXXXXXGLPDMTNMTAAEKKRVKAKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQATPPSPGQPAASGAPADGSSTXXXXXXXXXXXXLVARVLAEEAEWLLGTG-GLAGAVAELVRLAEDAETGSLGARVCAAKALSLTTAEEGR-EQAVRIVREGLGG---RGVTVPGCATAVEAVRGIVGED---GSAAVDALREVCAKTFPNAEVF 3120
            A+IPDNRKL K+E DLF+SI+K YE K+YKKGLKAA+++L+K+P+HGET AMKGL LN + +KEEA++ V++GLR D+RSHVCWHV+GLLHRS+RN+ EAIK YLNAL+ +  N+QILKDLA LQ+Q+R++ GFVETRRK+L     L+ +W  + +ANH++G+    +  ID+F+ TL     ++ +  +   EL+LYK + L  AG  +EAL  LE     VMD L W  ++  LLL   + E A + YR LL    E+Y +H G QCA+L+                LPS A   AG L EA  + L   Y  L      S    ++PLTFLEGE  ++ +DAYMRR+L +G+P+LG++L+++F  +          D + G     +      DA+DLR +   Q+V  L   ++E+L  TG FP+        ++G   P                TL WA +L+ QL E+ G + EA   LEEC A         LDFLQR+ R+L+K G +T AA  +D AR LD +DRY+N++ TKYLLRAGQ+  A+  IA+F +HEGDPQ  L +MQC W+ELEWA A    A KP          A+K+ +AV  HF DFVEDQFDFH YC+RK+TLR+Y+ +LR+ D L +   Y  A+  ++  Y   L +  E  G        G      MTAAEKK+ KA       XXXXXXXXXXXXXXXX      XXXXXXXXX                            VD DP G+ L+E++PL E  R+VA L+ HAG  VETH+LA+DVA KRGK LLA +A+IR  AL P +P++  RT+  +          G+    G   +  ++              A V+  E + LLG    L   V E V  A      SL   + AA+ ++L   E G  E A+ ++RE L     RG+TV G    VE    +VG++   GSA V  ++++C + FP+A  F
Sbjct:    7 AAIPDNRKLSKKEHDLFRSIVKFYETKQYKKGLKAADSILRKYPSHGETQAMKGLILNCMERKEEAYELVKQGLRNDVRSHVCWHVFGLLHRSDRNHGEAIKCYLNALRIDTSNMQILKDLANLQVQMRDLDGFVETRRKILSENCKLKVHWIGFVLANHLSGDLGMALSVIDSFLGTL-----EKRERGFEEGELVLYKAMLLEQAGRKEEALSWLESQKSFVMDGLAWRTRRAHLLLASEQFEKALEAYRALLAENSENYEYHLGWQCALLRRDSSNSAAMFAQPQASLPSSA---AGDLDEAASQQLLAAYGELARAEPHSLVCEKVPLTFLEGEAFKTRVDAYMRRHLARGLPALGSELAALFRTE----------DPENGRRIQAK------DAYDLRKNKRFQIVQLLVDEYIETLAMTGAFPSPTTSVAPCQNGSHPPSSSPSPSTSQAFDVTTTLLWAKYLKVQLLESAGEIPEALKLLEECLAACGEDTGAKLDFLQRRARLLKKGGRVTDAAVVMDEARQLDLSDRYLNNQTTKYLLRAGQVEAAQNVIALFAKHEGDPQVYLTDMQCMWYELEWAHATFSEATKPSGGGRALIAKALKRYVAVEKHFADFVEDQFDFHNYCVRKMTLRAYVDVLRLEDGLLAHPYYLAAARGMLDCYMAVLEMPKEEEG------VEGKDAYAGMTAAEKKKEKAXXXXXXXXXXXXXXXXXXXXXXXRVANAGXXXXXXXXXEEGKGKSTTNKKGGDGGKGV--------VDEDPEGMKLIEREPLTEMKRVVAYLTRHAGKVVETHMLAYDVACKRGKALLALQALIRAHALRPMHPDVFRRTVHFWTGM-------GESGGEGGKQEWIASLHPTS---------AAVIDAEKQRLLGEKKNLGSYVTEYVEKARA--WSSLPHVLAAARGVALAKTEPGATEVAIGLIREELQKGQCRGLTVKGLRQVVE----VVGKELDAGSATVAEMKKLCHQYFPDALEF 955          

Query:  289 YERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDAGMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALK---LRACELPSGALRAAGKLGEAEVETLKELYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTG-RFPTAEGEKDGDKEPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGS--GXXXXXXGLPDMTNMTAAEKKRVKAKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPRNPELLLRTI 2658
            YE+K+Y++ LK+A+ VLKKFP HGETLAM+GLTLNAL KKEEA+DHV+RGLR DLRSHVCWHVYGLL+RS+RNYAEAIK YLNALK + +NLQIL+DL+ LQ+Q+++  GFVETRRK+L LKSN + +W +YAV N + G  E+    ++ ++ T + D  +     Y  SEL+L++N A++++G + EAL  L+    KV+D   +   KG  LL LGRH DA  +YRE L+   E+Y +HRG Q A+L L      ++L    L+   LPS  L     L  A+V TL E Y  L E +  SPA  RI L FL   E +  L AY+   LRKG P+LGTDL ++       P  T          KLG  + +  D  D+   P+ Q  + +    + S R  G   P   G      E    L WA+FL+ QL E  G L EA    EEC    PT +D   RKGR+L+K+G    AAE VD AR +D ADRY+N+KATKYLLRA ++ +AE TIA+FTRHEGDPQ+NLFEMQCSW+ELEWAE+Q R  K GLA+KK  AV  HFEDF+EDQFDFHTYC+RK TLR+Y+ +LRM   ++S + ++R +  ++  YL L+D+ P S         G  +  + TAA+     AK      XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX     DP+G  L  +DPL EAA+   LL+  A   ++TH+L++DV ++RGK L+A RA+++G  + P++ EL  R +
Sbjct:   16 YEQKQYRRALKSADQVLKKFPQHGETLAMRGLTLNALDKKEEAYDHVKRGLRNDLRSHVCWHVYGLLYRSDRNYAEAIKCYLNALKWDRDNLQILRDLSLLQVQMQDYDGFVETRRKILTLKSNNKMHWISYAVGNLLGGRCESAAHIVNTYLNT-EVDTGEGGGPGYEDSELVLFRNQAIAESGKLDEALADLDAIKTKVLDMRAYLSMKGTYLLKLGRHGDAAAVYREALELNAENYDYHRGYQAALLTLEGDALADSLPGGALKFTALPSSELA----LDAAQVATLVEAYAKLTEAYPRSPAVKRIQLAFLPEAERQERLRAYIVNALRKGKPNLGTDLRTMLRV----PHPT----------KLGFLA-LAKDPLDVATLPLTQFFLGVADECIASTRENGGALPAWAGAPPTGGESPSALLWAMFLKVQLLEAMGMLAEALALCEECITHTPTAIDLYMRKGRLLKKLGDTQEAAEVVDFARKIDLADRYINNKATKYLLRADRVEQAEGTIALFTRHEGDPQYNLFEMQCSWYELEWAESQQRQRKYGLALKKFFAVDKHFEDFMEDQFDFHTYCLRKGTLRAYVNLLRMASGVQSHEFFQRTAKGIITTYLALYDD-PASMVAVEPKTNGAAENDDATAADTSDKPAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----DPVGAKLAARDPLEEAAKFCKLLNLRAAGAIDTHVLSYDVCVRRGKPLMALRALVKGYEIAPKDAELFRRIV 786          

Query:  238 RKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDA-GMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRG-DEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVETLKELYRG-LRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKDGDKEPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGSGXXXXXXGLPDMTNMTAAEKKRVKAKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQATPPSPGQPAASGAPADGSSTXXXXXXXXXXXXLVARVLAEEAEWLLGTGGLAGAVAELVRLAEDAETGSLGARVCAAKALSLTTAEEGREQAVRIVREGLGGRGVTVPGCATAVEAVRGIVGEDGSAAVDALREVCAKTFPNAEVFKSFS 3132
            R LPK+EADLFKS++K YE K+YKK +K+A+ +LK+FP HGETL MKGLTLN++ K+EEAH  V++GL  D+RSHVCWHV+GLLHRS+RNY EAIK+Y  AL+ +PENLQIL+DL+ LQIQ+R++KGFV TR  +L LK N + NW A+A+A H+ G+    V  ID ++ TL  +     ++ +  SEL +Y+N  L++    + EAL+HL+ C + ++D   W + K    L LG++E+A + +  +  RG  EDY  H G  CA+LKL    C +ALKLR     +  +     L + E +TL + Y G L E    S A  RIPL+ L G++L+ ++ +Y R+ L KGVPSLG+DLS++F                   EK GR   +  D  D+R H    M++ L   ++ SL S  +F  A+GE++   E   T+ WA +LRA L E  G   +     ++C    PT +D  + K R+L+  G    AA+ +D  R LDK DRY+N++ TKY+L+A +   A + IA+FTRHEG+P+ NL++MQC+W+ELE A    R G+ G ++KK +A+  HFEDF EDQFDFH+YC+RKVTLR+Y  +LR  D+L  Q+ Y +A+  ++R Y+ L+D     G        PD + MTAA++K+ KA A     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX                        VD DP G  LL++DPL EA +  A LS HA   + T +  +DVA++R K L+A +A+ + +A++  + EL  R +    + ++   +                            ++  VLA E   LL    L+  V+E    A+      L  RV  AK L  T     +E +  I+  GL GR V+V  C  A+  +  +    GS A DA  E  AK      +  +FS
Sbjct:   14 RPLPKKEADLFKSVVKHYECKQYKKVIKSADTILKRFPNHGETLCMKGLTLNSMSKREEAHALVKQGLMKDMRSHVCWHVFGLLHRSDRNYNEAIKAYKQALRIDPENLQILRDLSLLQIQMRDIKGFVVTRNTILTLKPNQKINWLAFALAKHLNGDLRGAVSVIDIYLGTLN-EGSLELEKGFESSELAMYRNKILAEIPDNLDEALNHLDACKNVIVDMGAWLMSKATFQLKLGKYEEALETFVAMFQRGLTEDYRVHTGYMCALLKLNADDCADALKLRG----TNTVATMRPLTDDERKTLIDAYTGDLLESHPRSRAVRRIPLSILVGDKLQDAVASYCRKGLTKGVPSLGSDLSAMFL-----------------VEKDGR-YVLADDPADIRAHSNFSMLVGLVDGYISSLLSHSKFSDADGEEE---ESPSTVLWAWYLRAFLHELAGEYMDGIALADKCIEHTPTAVDVYELKARLLQAAGDKGAAADCLDKGRELDKQDRYINNQTTKYMLQADRDSVARERIALFTRHEGNPEQNLYDMQCTWYELELAACMARKGQWGRSLKKYMAIDKHFEDFHEDQFDFHSYCIRKVTLRAYSDVLRFEDNLWGQQYYCQAAEGIIRNYVFLYDNPSAVGVEEE----PDYSEMTAAQRKKAKAIAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPSV---------------------VDEDPDGEELLKRDPLEEAKKYSATLSKHAPNRISTWMGQYDVAIRRKKVLMALQALFKAKAIDKESNELFTRIVDFVQKVESEKEA--------------------------NPIIKEVLASETTTLLEGKSLSDFVSEAASRAKSDALTDLPKRVAVAKGLIATNVGTVKEASSLIIDGGLEGRKVSVDTCRDALRCLTFL----GSDAEDAKTEWVAKVKEKFPLMTNFS 900          

Query:  235 NRKLPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDAGMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVE-TLKELYRGLRERFEG-SPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMDLTKSFVESLRSTGRFPTAEGEKD-GDKEPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGSGXXXXXXGLPDMTNMTAAEKKRVK---AKARRDAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLEKDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALE 2625
            +++LP +E+ LF+SI+K YE K+YKKGLKAA+A+LKK P HGETLAMKGLTLN +G+K+EA++ V+ GLR DLRSHVCWHV+GLL+RS+RNYAEAIK Y NA++ +PENLQIL+DL  LQ+Q+R++KGF ETRR +L LK N + NW  +A+A+H+ GN +  +  I+ +  TL+G+     +  Y  SE+ LY+N  + +AG I++AL HLEE  D++ D L W  KKG+ LL L R++DA   + ELL+   ++Y FHRGLQCAVLK          + +   LPS  +  + +   A++E  L + Y   +      S  + R PL F  G E     D Y+++ L K VPSLG DL  ++              AD  + K+                     + +L   +++SL +  + P  +G+        E+ L W  +L AQ  +  G   +A + +E+C   +P++LDF QRK R+L+ MG L +AA+ +   R LD ADRY+N+KAT+YLL A ++ +A+ TIA+FTRHEGDPQ NLFEMQC W+E+E  ++Q+R  K GLA+K+  AV  HF DF+EDQFDFHTYC+RK+TLR+Y+ MLR+ D++ S+  +  A+   +  Y  L D+     XXXXXX      NM+AAEKK+     AKAR+                                                             P D DPLG  L EK  L EA R V++L  +A   V+TH+ AFD+A+++ K+LL  +A+++ + +E
Sbjct:    5 SKQLPAKESALFRSIVKCYEIKQYKKGLKAADAILKKHPEHGETLAMKGLTLNCMGRKDEAYELVKSGLRHDLRSHVCWHVFGLLYRSDRNYAEAIKCYRNAIRIDPENLQILRDLYLLQVQMRDLKGFAETRRTMLTLKPNNRNNWIGFAIAHHLVGNFQMAIDIIEKYFSTLEGEH----EANYEDSEIHLYQNQLIEEAGDIEKALKHLEENKDQITDTLFWRQKKGQFLLQLERYDDARAAFEELLEINFDNYEFHRGLQCAVLKRKDLFVARPTQKKT-PLPSEVVDFSKETNGAQLEKALADFYTEKKTTIGAESLISLRFPLDFTRGAEFEKYADVYLKKQLNKNVPSLGADLKPLY--------------ADKDKTKV---------------------LEELILGYLKSLEA--KKPLDQGDNSLAANATEKVLLWTNYLAAQHYDRLGNHAKAMEYIEKCIKQEPSLLDFFQRKARILKHMGDLNQAADVMVEGRKLDLADRYINNKATEYLLHADRVEEADATIALFTRHEGDPQQNLFEMQCMWYEIECGKSQLRQQKYGLALKRFFAVEKHFNDFIEDQFDFHTYCIRKMTLRAYIQMLRLCDEIYSRPFFVEAAHGAIACYEALADKEDKEXXXXXXXXXXXX-NMSAAEKKKXXXXXAKARK---------------------AEFKRKEEEELNAKLHKEAEEKEREAAKNGKPKANAGPTRPKDDDPLGEKLAEKPALEEAWRFVSILQQYASEDVKTHVAAFDIALRKKKFLLCLQALLKAQTVE 743          

Query:  244 LPKREADLFKSILKLYERKEYKKGLKAAEAVLKKFPTHGETLAMKGLTLNALGKKEEAHDHVRRGLRADLRSHVCWHVYGLLHRSERNYAEAIKSYLNALKHEPENLQILKDLAALQIQIREVKGFVETRRKLLGLKSNLQQNWTAYAVANHVAGNAETTVQAIDAFVKTLKGDRHQRADERYPHSELLLYKNLALSDAGMIQEALDHLEECSDKVMDKLGWTIKKGELLLTLGRHEDAEKIYRELLDRGDEDYTFHRGLQCAVLKLPPKQCEEALKLRACELPSGALRAAGKLGEAEVETLKELYRGLRERFEGSPAAARIPLTFLEGEELRSSLDAYMRRYLRKGVPSLGTDLSSVFERQGAPPSVTAGGDADGGEEKLGRPSPVVSDAFDLRNHPVQQMVMD-LTKSFVESLRSTGRFPTAEGEKDGDKEPEETLAWALFLRAQLEETTGFLQEAYDTLEECAALQPTMLDFLQRKGRVLRKMGALTRAAEAVDSARMLDKADRYMNSKATKYLLRAGQIPKAEQTIAIFTRHEGDPQHNLFEMQCSWFELEWAEAQIRAGKPGLAMKKALAVHTHFEDFVEDQFDFHTYCMRKVTLRSYLGMLRMVDDLRSQKSYRRASALLVRAYLRLHDERPGSGXXXXXXGLPDMTNMTAAEKKRVKAKARR-DAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPVDPDPLGLTLLE-KDPLPEAARLVALLSAHAGAYVETHLLAFDVAMKRGKYLLAARAVIRGRALEPRNPELLLRTIQLYHEAQATPPSPGQPAASGAPADGSSTXXXXXXXXXXXXLVARVLAEEAEWLLGTGGLAGAVAELVRLAEDAETGSLGARVCAAKALSLTTAEEGREQAVRIVRE 2976
            LP +E +LFK ++K YE K+YKKGLKAA+ VLKKFP HGETLAMKGLTLN L +KEEA+D+VRRGL+ DL+SHVCWHVYGLL+R++RNY EA K Y NALKH+P N QIL+DLA LQ+Q+R+  GFVETRR+LL  K N + NW A+A+A H++G     V+ I A+ KT++        ERY HSE+LLYK + + +AG  ++AL  L+E SD+++DKL    ++  LLL L R+ +AEK YR LL    ++Y ++RGL            E AL L+A         +AG   + +V  LK LY+ L ERF  S A  RIPL F+EGE+ R ++  Y+  +LRKGVPSL +DL  ++                                    N P +  +MD + K F  SLR  GRFP        D EP  TL W LFL AQ  +       A + +EE     PT+ D    K R+LR  G    AA   + AR LD ADRY+N++A K  L A Q+  AE+T A+FT+ +G+  ++LF+MQC W+E+   ++ +R    G A+KK LA+  H+ D +EDQFDFHTYC+RK+TLR+Y+ MLRM D L S K + + +A  +R Y+ L D +P  G      G    + ++A E+K+++AK R+ +AK         XXXXXXXXXXXXXXXXXX                               P DPDP G  L + +DPL E+ + + LL  HA   +ETHLLAF++ +++ K LLA +AV R  +++  +P++    + L+H    T P+P   +A                      LV RV+AEE + +    G +  + E         +GSL  R  AA+ + L       E AV IV E
Sbjct:    5 LPPKENNLFKLVVKSYETKQYKKGLKAADQVLKKFPEHGETLAMKGLTLNCLERKEEAYDYVRRGLKNDLKSHVCWHVYGLLYRADRNYREAAKCYRNALKHDPGNNQILRDLANLQVQLRDTAGFVETRRELLTTKPNNKNNWLAFAIAQHLSGRQHVAVEIITAYEKTVE---EYLDSERYEHSEMLLYKAMLMEEAGQFEQALRQLKENSDQIVDKLSIREQRAALLLKLNRNAEAEKEYRYLLAINSDNYNYYRGL------------EAALGLQAS--------SAGTWDDNQVAKLKTLYKELLERFPRSAAVKRIPLDFIEGEDFRKAISQYLPAFLRKGVPSLYSDLKPLY------------------------------------NQPGKAAIMDDVFKRFETSLREEGRFPAESSSSSTDPEPPTTLLWTLFLLAQHYDRRRLYDVALEKVEEAIKHTPTVPDLYLVKARILRHGGDAPAAAALAEEARSLDLADRYLNNEAVKRFLGADQVEDAERTAALFTK-DGEQHNSLFDMQCMWYEVASGDSHLRQSAYGKALKKYLAIEKHYADMIEDQFDFHTYCLRKMTLRAYIKMLRMEDHLHSFKFFCKGAAGAIRTYIALFD-KPAQGDNDDADGAN--SGLSALERKKLRAKQRKAEAKAKKAEETKRXXXXXXXXXXXXXXXXXXGGKKPKAEAVK--------------------PADPDPHGDKLAQVEDPLSESVQYLQLLQQHAAQAIETHLLAFELYIRKKKLLLALQAVKRLVSIDVTHPDVHRSLVTLFHTVD-TSPAPDSESAE---------------------LVHRVIAEERKEITALAGQS--LQEYNEAFLKEHSGSLLHRAAAAEVVVLLDCSRTAE-AVGIVEE 810