prot_Ecto-sp6_S_contig97.18702.1 (polypeptide) Ectocarpus species6 EcLAC_371

BLAST of mRNA_Ecto-sp6_S_contig97.18702.1 vs. uniprot
Match: A0A6H5JQY0_9PHAE (Protein kinase domain-containing protein n=2 Tax=Ectocarpus TaxID=2879 RepID=A0A6H5JQY0_9PHAE)

HSP 1 Score: 1139 bits (2946), Expect = 0.000e+0
Identity = 594/670 (88.66%), Postives = 609/670 (90.90%), Query Frame = 0

Query:   73 FIDTGAFCAVYACKYRGWSVVAKRVRQDLPLSERRVALANLWSEYDCLRSLSHRNIVDVYGMCRVRCREDYDDWKEIDVCLLLEKLAFGTVGHLFETIVPVDKNLRTTMARARKMKMVPFRCRLQRTLELAQALEYVHGGSGIGPIMHRDIKSVNVGFAQNGRLKLMDFGLSKMAPPGCEGDDTYKMTGEVGSYRYMAPELVKHEPYNVKVDIYSWAILSWEILAIEKPYSDMSESTFIKRVIKGGDRPEVRRSWPNRLCTLLASAWHADHTKRPVAAEIVTVLKIIYAELSTKDRRKRPSYESTAAPGGRRGSLRRRDKSNRRHSWSQLSSRTPASAFSGTRLPSRSNETGNGGGSAARDDSNRLFAPSFSCPSPGCDSPLDRSSSLPLPLRPTSSPTYFALAKRRWRSIRRKSRGPDLFEGVASAPPNGEARGAARGGKAGRGSNVKVPTEQGLSEGTRCSRPAPESLLVASALKSKESDETNSEGQSRAPEWTTSAVGVADDTSTCGGGVGGSCSGHRCQQHQAIISKREIIADALRRETAGLVSSGAADAPSWSQQVCQSRTTEITTAPKTEVGAEARHDSQRRXXXXXXXXXXXXEPAAAANRAKTALDVGGQWAPEEERVRSVSDVSRRVRRNSSVSKLWPTSASTNGGGTTGAELVATAVASE 742
            FIDTGAFCAVYACKYRGWSVVAKRVRQDLPLSERR ALANLW+EYDCLRSLSH NIVDVYGMCRVRCREDYDDW E DVCLLLEKLAFGTVGHLFETIVPVDKNL+TTMARARKMKMVPFRCRLQRTLELAQALEYVHGGSGIGPIMHRD+KSVNVGFAQNGRLKLMDFGLSK APPG E DDTYKMTGEVGSYRYMAPELVKHEPYNVKVDIYSWAILSWEILAIEKPYSDMSE TFIKRV+KGGDRPEVRRSWPN+LCTLLASAWHADH KRPVAA+IVT LKIIYAELS KDRRK+PSYEST+A  GRRGSLRRRDKSNRRHSWSQLSSRTPASAFSGTRLPSRSNETGNG GSA RDDS RLFAPS S PSPGC S LDRS+SLPLPL PT SPT+ ALAKRRWRSIRRKS GP LFEGVASAP NGEA G+A GGK GRGS+VKV TE+  SEGTR SRPAPESLLVAS LKSKESDET SEGQ RAP WTT+AVGVADDTSTCGGGVGGSC GHRC QHQAIISKREIIADALRRETAGLVSSGAADAPSWSQQVCQSRTTEITTAPK EVG EARHD QRR            EPAAAANRAKTA  VGGQW PEEERVRS SDVSRRVRRNSSVSKLWPTSASTNGGG  GA+LVA AVASE
Sbjct:    7 FIDTGAFCAVYACKYRGWSVVAKRVRQDLPLSERRAALANLWTEYDCLRSLSHPNIVDVYGMCRVRCREDYDDWNERDVCLLLEKLAFGTVGHLFETIVPVDKNLKTTMARARKMKMVPFRCRLQRTLELAQALEYVHGGSGIGPIMHRDVKSVNVGFAQNGRLKLMDFGLSKKAPPGGEDDDTYKMTGEVGSYRYMAPELVKHEPYNVKVDIYSWAILSWEILAIEKPYSDMSEYTFIKRVVKGGDRPEVRRSWPNQLCTLLASAWHADHAKRPVAADIVTALKIIYAELSPKDRRKKPSYESTSALSGRRGSLRRRDKSNRRHSWSQLSSRTPASAFSGTRLPSRSNETGNGRGSATRDDSGRLFAPSSSRPSPGCVSSLDRSNSLPLPLHPTCSPTFVALAKRRWRSIRRKSHGPGLFEGVASAPLNGEAWGSAPGGKGGRGSSVKVATERDSSEGTRWSRPAPESLLVASVLKSKESDETGSEGQGRAPVWTTTAVGVADDTSTCGGGVGGSCGGHRCPQHQAIISKREIIADALRRETAGLVSSGAADAPSWSQQVCQSRTTEITTAPKVEVGEEARHDCQRRSGGVGGDHER--EPAAAANRAKTAHGVGGQWVPEEERVRSASDVSRRVRRNSSVSKLWPTSASTNGGGIKGAKLVAAAVASE 674          

BLAST of mRNA_Ecto-sp6_S_contig97.18702.1 vs. uniprot
Match: D8LLC2_ECTSI (Serine/threonine-protein kinase CTR1 n=1 Tax=Ectocarpus siliculosus TaxID=2880 RepID=D8LLC2_ECTSI)

HSP 1 Score: 411 bits (1057), Expect = 2.910e-134
Identity = 197/255 (77.25%), Postives = 221/255 (86.67%), Query Frame = 0

Query:   60 ITSLPVVTLTDMEFIDTGAFCAVYACKYRGWSVVAKRVRQDLPLSERRVALANLWSEYDCLRSLSHRNIVDVYGMCRVRCREDYDDWKEIDVCLLLEKLAFGTVGHLFETIVPVDKNLRTTMARARKMKMVPFRCRLQRTLELAQALEYVHGGSGIGPIMHRDIKSVNVGFAQNGRLKLMDFGLSKMAPPGCEGDDTYKMTGEVGSYRYMAPELVKHEPYNVKVDIYSWAILSWEILAIEKPYSDMSESTFIKRV 314
            I SLPVV L  M+FI  GAFCAV+ACKYRG+SVVAKRVR+DLPL ERR AL NLW EYDCL+ L H N+++ YGMCRVRCRE YDDW E DVCLLLE+LAFGTVGHLF T   V+KNL+T MAR+RKMKMVPFRCRL R LELAQALEYVHGGSGIG +MHRDIKS+NVGFAQNG LKL+DFGLSKM P     DDTY+MTGEVGSYRYMAPELVKHEPYNVKVD+YSWAILSWEILAI++PY+DM++++FI  V
Sbjct:  127 IASLPVVELGSMKFIAHGAFCAVFACKYRGFSVVAKRVREDLPLPERRKALENLWQEYDCLQPLQHPNVIEAYGMCRVRCREGYDDWNERDVCLLLEQLAFGTVGHLFGTTYSVEKNLKTAMARSRKMKMVPFRCRLHRALELAQALEYVHGGSGIGSMMHRDIKSMNVGFAQNGCLKLLDFGLSKMVPLDSTEDDTYEMTGEVGSYRYMAPELVKHEPYNVKVDVYSWAILSWEILAIDRPYADMNQASFINEV 381          

BLAST of mRNA_Ecto-sp6_S_contig97.18702.1 vs. uniprot
Match: A0A835ZE86_9STRA (Kinase-like domain-containing protein n=1 Tax=Tribonema minus TaxID=303371 RepID=A0A835ZE86_9STRA)

HSP 1 Score: 175 bits (444), Expect = 6.290e-43
Identity = 110/300 (36.67%), Postives = 155/300 (51.67%), Query Frame = 0

Query:   68 LTDMEFIDTGAFCAVYACKYRGWSVVAKRVRQDLPLSERRVALANLWSEYDCLRSLSHRNIVDVYGMCRVRCREDYDDWKEIDVC--LLLEKLAFGTVGHLFETIVPV---DKNLRTTMARARKMKMVPFRCRLQRTLELAQALEYVHGG--SGIGPIMHRDIKSVNVGFAQNGRLKLMDFGLSKMAPPGCEGDDTYKMTGEVGSYRYMAPELVKHEPYNVKVDIYSWAILSWEILAIEKPYSDMSESTFIKRVIKGGDRPEVRRSWPNRLCTLLASAWHADHTKRPVAAEIVTVLKIIY 360
            L ++ ++  GA C +Y+ +YRG  VV K  R D    E  +A  +L  E + L  L HR+I+ + G             +EI     L+LE L  GT+        P    +      +   +K +       L+R +ELA+ALEY+H     G   ++HRD+K  N+GF  +G LKL DFGL++        +  Y MTGE GS RYMAPE+V+  PYN KVD+Y++ +L WE+L   + +  MS   F +RV+ GG RP +  SWP  L  L+   WHAD  KRP    I   LK IY
Sbjct:  140 LKNLFYMTEGAMCRIYSAEYRGAKVVVKLPRDDCEDPE--IAEHDLEVELEVLWGLDHRHIIKLLGA----------GLREIPPYRFLVLEYLEMGTLADRLNAGAPPGQEETGYNKIIKGTKKYQRFHQVTMLERAMELAEALEYLHHSVCGGAAFVVHRDLKPDNIGFKADGTLKLFDFGLARCVKRRARVNARYDMTGETGSMRYMAPEVVESLPYNEKVDVYAFGLLLWEMLQYRRVFEGMSVGDFYQRVVNGGIRPPLDSSWPPALRKLIDLCWHADVDKRPDFHYIAAQLKDIY 427          

BLAST of mRNA_Ecto-sp6_S_contig97.18702.1 vs. uniprot
Match: A0A6H5L2R6_9PHAE (Protein kinase domain-containing protein n=1 Tax=Ectocarpus sp. CCAP 1310/34 TaxID=867726 RepID=A0A6H5L2R6_9PHAE)

HSP 1 Score: 165 bits (418), Expect = 2.050e-39
Identity = 106/300 (35.33%), Postives = 161/300 (53.67%), Query Frame = 0

Query:   68 LTDMEFIDTGAFCAVYACKYRGWSVVAKRVRQDLPLSERRVALANLWSEYDCLRSLSHRNIVDVYGMCRVRCREDYDDWKEIDVCLLLEKLAFGTVGHLFETIVPVDKNLRTTMARARKMK------MVPFRCRLQRTLELAQALEYVHGGSGIGPIMHRDIKSVNVGFAQNGRLKLMDFGLSKMAPPGCEGDDTYKMTGEVGSYRYMAPELVKHEPYNVKVDIYSWAILSWEILAIEKPYSDMSESTFIKRVIKGGDRPEVRRSWPNRLCTLLASAWHADHTKRPVAAEIVTVLKIIYA 361
            L+ + ++  GA C +Y+ +  G  V  K  R+D    E  VA  +L  E D L+ +SH++I+ + G      RE     ++    L+LE L  GT+    +       N      R ++ K      MV     L+R++ELA ALE++H       I+HRD+K  NVGF  +G LKL DFGL+++       +  Y+MTGE GS RYMAPE+V+  PYN KVD+Y++ +L WE+L   + +  M  + F +RV+  G RP +  +WP  L  L++  WHAD  +RP    I   L+I+Y+
Sbjct:  208 LSKVTYMTMGAMCEIYSAELDGVKVAVKIPRKDC--EEPAVAEHDLEVELDVLKRVSHKHILGLIGAGN---RE-----QKPHRFLVLEFLELGTLADKLDGDAEEAANGSAFARRQKRTKKYLDFYMVTM---LERSMELALALEHLHYHMPDMFIVHRDLKPDNVGFKADGTLKLFDFGLARVVKRRNRVNARYEMTGETGSMRYMAPEVVESLPYNEKVDVYAFGLLLWEMLEDRRVFDGMGVTDFYERVVNAGARPNLDSAWPQDLRKLISQCWHADVDRRPNFRTIAERLRILYS 494          

BLAST of mRNA_Ecto-sp6_S_contig97.18702.1 vs. uniprot
Match: D7FS28_ECTSI (Protein kinase domain-containing protein n=1 Tax=Ectocarpus siliculosus TaxID=2880 RepID=D7FS28_ECTSI)

HSP 1 Score: 160 bits (406), Expect = 2.420e-39
Identity = 104/291 (35.74%), Postives = 155/291 (53.26%), Query Frame = 0

Query:   77 GAFCAVYACKYRGWSVVAKRVRQDLPLSERRVALANLWSEYDCLRSLSHRNIVDVYGMCRVRCREDYDDWKEIDVCLLLEKLAFGTVGHLFETIVPVDKNLRTTMARARKMK------MVPFRCRLQRTLELAQALEYVHGGSGIGPIMHRDIKSVNVGFAQNGRLKLMDFGLSKMAPPGCEGDDTYKMTGEVGSYRYMAPELVKHEPYNVKVDIYSWAILSWEILAIEKPYSDMSESTFIKRVIKGGDRPEVRRSWPNRLCTLLASAWHADHTKRPVAAEIVTVLKIIYA 361
            GA C +Y+ +  G  V  K  R+D    E  VA  +L  E D L+ +SH++I+ + G      RE     ++    L+LE L  GT+    +       N      R ++ K      MV     L+R++ELA ALE++H       I+HRD+K  NVGF  +G LKL DFGL+++       +  Y+MTGE GS RYMAPE+V+  PYN KVD+Y++ +L WE+L   + +  M  + F +RV+  G RP +  +WP  L  L++  WHAD  +RP    I   L+ +Y+
Sbjct:    4 GAMCEIYSAELDGVKVAVKIPRKDC--EEPAVAEHDLEVELDVLKRVSHKHILGLIGAGN---RE-----QKPHRFLVLEFLELGTLADKLDGDAEEAANGSAFARRQKRTKKYLDFYMVTM---LERSMELALALEHLHYHMPDMFIVHRDLKPDNVGFKADGTLKLFDFGLARVVKRRNRVNARYEMTGETGSMRYMAPEVVESLPYNEKVDVYAFGLLLWEMLEDRRVFDGMGVTDFYERVVNAGARPNLDSAWPQDLRKLISQCWHADVDRRPNFRTIAERLRTLYS 281          

BLAST of mRNA_Ecto-sp6_S_contig97.18702.1 vs. uniprot
Match: A0A7S4ER90_CHRCT (Hypothetical protein n=2 Tax=Chrysotila carterae TaxID=13221 RepID=A0A7S4ER90_CHRCT)

HSP 1 Score: 162 bits (411), Expect = 3.350e-39
Identity = 98/290 (33.79%), Postives = 162/290 (55.86%), Query Frame = 0

Query:   72 EFIDTGAFCAVYACKYRGWSVVAKRVRQDLPLSERRVALANLWSEYDCLRSLSHRNIVDVYGMCRVRCREDYDDWKEIDVCLLLEKLAFGTVGHLFETIVPVDKNLRTTMARARKMKMVPFRCRLQRTLELAQALEYVHGGSGIG-PIMHRDIKSVNVGFAQNGRLKLMDFGLSKMAP-PGCEGDDTYKMTGEVGSYRYMAPELVKHEPYNVKVDIYSWAILSWEILAIEKPYSDMSESTFIKRVIKGGDRPEVRRSWPNRLCTLLASAWHADHTKRPVAAEIVTVLKII 359
              +  GAFC VY  ++ G S VA +V +   L E ++AL +L SE   L  L H+NI+ V         E  D  +     ++L++LA      +   ++P  K       R R++K  P    ++ +L+LA+AL Y H  +  G  ++HRD+K  N+GF  +GRL L DFGL+K+ P  G +  +   MT + GS RYMAPE+   EPY+   +++SWAI++W++ + +KP+  ++ ++ ++ V K G RPE++  WP     +LA++W A+ ++R    E+V  LK +
Sbjct:  174 RLVGGGAFCDVYIAQFEG-SEVALKVLKPQHL-ESKLALKDLESEARLLHRLKHKNILQVLSE---GVHETEDGARPF---VVLQRLA-----SVLTNLLPGAKESTPIWERHRQIKAWPLSRAIEVSLQLAEALHYCHYEAIAGYALLHRDLKPDNIGFGADGRLLLFDFGLAKLIPCKGLDDSEPRSMTAQTGSGRYMAPEVALGEPYHRPSEVFSWAIIAWQLASHDKPFESLTVASHLREVAKNGRRPELKSKWPQAFKDMLAASWDAEPSRRRTFRELVPELKAL 450          

BLAST of mRNA_Ecto-sp6_S_contig97.18702.1 vs. uniprot
Match: A0A836C8Q0_9STRA (Serine/threonine-protein kinase CTR1 n=1 Tax=Tribonema minus TaxID=303371 RepID=A0A836C8Q0_9STRA)

HSP 1 Score: 159 bits (402), Expect = 8.210e-38
Identity = 96/283 (33.92%), Postives = 144/283 (50.88%), Query Frame = 0

Query:   68 LTDMEFIDTGAFCAVYACKYRGWSVVAKRVRQDLPLSERRVALANLWSEYDCLRSLSHRNIVDVYGMCRVRCREDYDDWKEIDVCLLLEKLAFGTVGHLFETIVPVDKNLRTTMARARKMKMVPFRCRLQRTLELAQALEYVHGGSGIG-PIMHRDIKSVNVGFAQNGRLKLMDFGLSKMAPPGCEGDDT--YKMTGEVGSYRYMAPELVKHEPYNVKVDIYSWAILSWEILAIEKPYSDMSESTFIKRVIKGGDRPEVRRSWPNRLCTLLASAWHADHTKRP 347
            L D EF+  G+ C +Y   Y+   V  K VR+D+P  +++     L  E D L  L H NIV + G              + +  +++E+L  GT+     + +    N+R    R R      +   +    +LA AL Y+H  +  G  ++HRD+K  N+ F   G LK++D GL+K+ P   +GD T  YKMTGE GS RYMAPE+   +PYN K D+Y + ++ WE+ A+ KP+  +    F + V+ G  +P V R+WP     LL   W  D  KRP
Sbjct:  197 LQDAEFLVNGSRCTIYTAFYKNLPVAVKLVRKDIP--DKKTVYGELNMETDILMRLHHPNIVKLIGA-----------GTQPERFMVIERLDGGTLAQRCGSAL----NIRDRRRRFRTKTPFTYLELVTCARQLAHALRYMHTEAVPGCMVIHRDLKPDNIAFDGMGNLKILDMGLAKVVPLA-DGDPTAVYKMTGETGSLRYMAPEVALRKPYNGKADVYGFGMILWEMAAMRKPFEGIGRELFFELVVNGTSKPPVDRNWPPEFGALLHKCWEKDPAKRP 461          

BLAST of mRNA_Ecto-sp6_S_contig97.18702.1 vs. uniprot
Match: A0A7S2HTU5_9STRA (Hypothetical protein n=1 Tax=Helicotheca tamesis TaxID=374047 RepID=A0A7S2HTU5_9STRA)

HSP 1 Score: 156 bits (394), Expect = 8.570e-38
Identity = 98/281 (34.88%), Postives = 155/281 (55.16%), Query Frame = 0

Query:   81 AVYACKYRGWSVVAKRVRQDLPLSERRVALANLWSEYDCLRSLSHRNIVDVYGMCRVRCREDYDDWKEIDVCLLLEKLAFGTVGHLFETIVPVDKNLRTTMARARKMKMVP---FRCRLQRTLELAQALEYVHGGSGIGPIMHRDIKSVNVGFAQNGRLKLMDFGLSKMAPPGCE-GDDTYKMTGEVGSYRYMAPELVKHEPYNVKVDIYSWAILSWEILAIEKPYSDMSESTFIKRVIKGGDRPEVRRSWPNRLCTLLASAWHADHTKRPVAAEIVTVLK 357
            A YA KY     ++  V++D    + R+A  ++  E   L +L H++I+ + G+ +        D  + D  L+L++L +G +    E  + + K   T M + R  K      F+ RL   L LA+A++Y+HG +    I++RD+K  NVGF   G +KL DFGL+K   P  +  + +YK+TG+ GSYRYMAPE+    PYN+  D+YS+ IL WEI++++ PY D S     + V   G RPE    WP  L  L+ S W A+  +RP  ++++ VL+
Sbjct:  147 ARYAIKY-----ISPDVKKDP--KKFRIAAMDMAVETHFLSALDHKHIIKLRGVGQ-------GDMFDQDYFLVLDRL-YGILTDKLEEWIALTKKYDTFMGKIRSGKAKKKRLFKDRLTAALNLAEAMDYIHGLN----IIYRDLKPDNVGFDLRGNVKLFDFGLAKELQPHQKLSNGSYKLTGQTGSYRYMAPEVANKLPYNLSADVYSFGILLWEIVSMDIPYDDFSIKMLCEMVANWGHRPECNPLWPANLQALMKSCWDANKGRRPPFSKVIAVLE 408          

BLAST of mRNA_Ecto-sp6_S_contig97.18702.1 vs. uniprot
Match: A0A4D9DDS7_9STRA (Protein kinase domain-containing protein n=5 Tax=Monodopsidaceae TaxID=425072 RepID=A0A4D9DDS7_9STRA)

HSP 1 Score: 157 bits (398), Expect = 1.370e-37
Identity = 97/298 (32.55%), Postives = 147/298 (49.33%), Query Frame = 0

Query:   68 LTDMEFIDTGAFCAVYACKYRGWSVVAKRVRQDLPLSERRVALANLWSEYDCLRSLSHRNIVDVYGMCRVRCREDYDDWKEIDVCLLLEKLAFGTVGHLFETIVPVDKNLRTTMARARKMKMVPFRCRLQRTLELAQALEYVHGGSGIGPI-MHRDIKSVNVGFAQNGRLKLMDFGLSKMAPPGCEGDDTYKMTGEVGSYRYMAPELVKHEPYNVKVDIYSWAILSWEILAIEKPYSDMSESTFIKRVIKGGDRPEVRRSWPNRLCTLLASAWHADHTKRPVAAEIVTVLKIIYAELS 364
            L ++EF+ +GAF  V++  Y+G +VV K +R+     E +V L  +  E   L  L H NIV+  G                              G  F  +  +D+ L   M    ++ M+     L   + + +AL Y+H  +  G + +HRD+K  N+ F ++G +KL+DFGL++  P G   ++ Y+MTGE GS RYMAPE+     YN K D+YS A+++W+++   KP+  MS   F   V+    RP V   WP  L +++  AW  D  KRP A E V  L  I   LS
Sbjct:   80 LENVEFLASGAFSHVFSAIYKGKNVVVKLLREQY--KESQVTLKQMRFEQTLLSQLDHSNIVEFIGTGVYN-------------------------GVPFTVLERLDETLNQRMGGEVRLTMLES---LTYAMAIGEALVYLHDAAISGHVTLHRDLKPDNLAFGESGSVKLIDFGLARSVPRGASINEVYEMTGETGSLRYMAPEVALGMLYNAKADVYSLALITWQMVQGTKPFQGMSRKDFFHHVVHRHFRPPVDPKWPPALSSIIVQAWDPDQLKRPTAREFVDTLGSIVRGLS 347          

BLAST of mRNA_Ecto-sp6_S_contig97.18702.1 vs. uniprot
Match: A0A7S0HE30_9EUKA (Hypothetical protein n=1 Tax=Phaeocystis antarctica TaxID=33657 RepID=A0A7S0HE30_9EUKA)

HSP 1 Score: 154 bits (388), Expect = 2.600e-37
Identity = 99/309 (32.04%), Postives = 161/309 (52.10%), Query Frame = 0

Query:   63 LPVV---TLTDMEFIDTGAFCAVYACKYRGWSVVAKRVRQDLPLSERRVALANLWSEYDCLRSLSHRNIVDVYGMCRVRCREDYDDWKEIDVCLLLEKLAFGTVGHLFETIVPVDKNLRTTMARARKMKMVPFRCRLQRTLELAQALEYVHGGSGIG-PIMHRDIKSVNVGFAQNGRLKLMDFGLSKMAPPGCEGDDTYKMTGEVGSYRYMAPELVKHEPYNVKVDIYSWAILSWEILAIEKPYSDMSESTFIKRVIKGGDRPEV-RRSWPNRLCTLLASAWHADHTKRPVAAEIVTVLKIIYAELSTK 366
            +PVV   +L    F+ +G FC V +    G  V  K +R+     +  +A+++L SE   + SL HR+++ V G+ +                  L  L    +  +  + +P   +  +   R R +K  P +  LQ  +ELA+AL Y+H  +  G  ++HRDIK  N+GF  +G L L DFGLSK+      G   +K+TG+ G+ RYMAPE+   +PY    ++YS+AI+ W++++ E PY+ +  + F +RV++ G RP +  ++WP  L  LLA  W    T+RP   E+   L+ I+  L  K
Sbjct:   85 VPVVEWSSLVGHRFLGSGEFCTVSSATLDGAPVAVKVLREIH--RDNALAISDLESETQIMISLRHRSVLRVLGVGKTGG---------------LPFLVLEILDSVLLSTLPKPADQTSLWVRRRSVKQWPLQRALQCGIELAEALRYIHSEAMPGFHVLHRDIKPDNMGFRADGSLVLFDFGLSKLVRIKA-GVTAHKLTGQTGAIRYMAPEVAMSQPYGTSAEVYSFAIILWQMISHEVPYAGLGSTAFHRRVVQEGFRPPLGNKAWPAPLSQLLAECWSRTPTERPAIEEVCRRLREIHDGLIVK 375