Query: 209 MLPCNHPLCRGCARQCLRQNQRCPQCLAAIPNLRMLQGRNTWIVEMVCSLKNCLNEVGVSLTQHAPVPPKYRDKPAPKTGAAGAAVXXXXXXXXXXXXXXXXXXXLSTVSCGGXXXXXXXXXXXGGARRKGGSRISNGAGRATSASTR-AESSSPHLSDNENAAAVPLPTSSPPARMPPPRPFVVGDLVFVEHRTWPGMNKHGGVALVTAVLDPPGSRYDVKYTVGQKHDRGVEARYVRSYAFPDETVGSRSRRGG----GGTRAGRQPGGGSGSARVSLPPRGRSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPRYEHAADDSGEPVGAEEEGPDKERTAVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSPVAAAA-----GDEGCGGCAEVPGHRHDDDEASRYDXXXXXXXXXXAAQGSHVSNTASTSTIREEGVERADGAGYSSEDGGGMDYGGGSYDDGHDHDSEAAAPRREGNI----DRDGEVKVPAEALS---RPDVSEKETGEGKQEDG-----------------REEATRIEEMNDLTD-----DRRKSLSVSGVGSGVAGGAADGPAAPLSPTARSNLPWRPPPQSDGLGNEQSAGGQRRRHDSP---------SSFPASGTRYTSDLMLAGAAEGLMALAANHRTA-----PAAAAGVEEAEEERRVE--GVEDTESEAETSTPPPQSPGDRSDVRLHQGSSNPRGEAAP----------PAGASLPTGLPAA---IAPSPLLSQSGNTSRPEQHQDYTPVASAAATTATAAGGNRQDNG------------------------GDYADP--TP-STCSMEAAEGTGGGDGGTRADTPIHSAASPSTASPPPLPPARPSPSQHTXXALQQXXXXXXXXXXXXXXXXXXXXXXNSSLASPVPSPPKLPSFKVGDLVSVPSRSSPGVNKEGGVAKVTLARPDGTFDVKYMVRQGREKGVAAAILSPYKVDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----TSAVRRTPRSNKGWCSPDIAAGQANAACLNYMLGDTQHPELDLDPDLGELLDPNEGKSSXXXXXXXXXXXXXXXXXXXXXXXXXVKSTTGAPTGKARRQRDXXXXXXXXXXXXXXXXXLGGDSDDGKAVSGWEIRDSSDGRRRKNSGSGTKRKHPARGSVEESDDRKRLARGNGAEKRLSGDSHSRGGSSQGXXXXXXXXXXXXXXXXXXXXXXXXSKKDVFDITTLTADPDSEDDAAARRLVAAAVDYDGASGSSGLEVFD-----------------ITALSPGSDVAGSGAPATKKRSRPSGGKEPARAAXXXXXXXXXXXXXXXXXXVGKKRRSGKDKGKSKAIGGKAGGSRSRGGGASSG--NEQEKVGL----VSGRRGRA--AAANPEAEKPVVLTLSGSTAEILTLANALVKSLGWRVEPKYTEAVTHVVCGTVQKNAKAKVRSAKFLRGVASGKWVVTEAWLQECKRRSGRVKEEAFEVSGDRKSAVPSAPTRSRLAHADPGRPGLFHGISFQFRGQFGTTGSPPLSELEAMLLDNGGRVVSTIESLFTSPVGAGGXXXXXXXXXXXXXXXXXXXXXXXXXXXRPRRVVIFQPSSESPEEDARVLEEDLASVVEAELSKQTSKACTLAAEGARARGGGSGRRGAGPDNTAIEVVKPIWLVDSVGCFRVLSPSVRHRLPSSG 5056
MLPCNHPLCRGCA QC +++QRCPQC+ IPNLRMLQGRN WIV MV LKN +N+VGVSLTQH+PVP KYRD P+PK+GAAG A XXXXXXXXXXXXXXXXX XXXXXXXXXXX R+ + S G A A T A +SSP +D++ A+ PP +PP +PFVVGDLV VE RTWPGMNKHGGV LV AVLDPPGSRYDVKYTVG K DRG+EAR+V ++AFP+ETVGSRSRRGG G TRA R+ GG G + S+ PRGRS P D G AEE+GP+++R ++PVA AA XXXXXXX A H N A EG +D A SSE+GGG G ++ HD D E D D P E D +E GEGKQ +G REE+ TD DR LS + + GG+ + PLSPT+R NLPWR S G G R R D P SS +G T L AAEGL+ALA+ P A E+AEE+ R++ GV+D +T P R+ L Q SS+ E AP A A+ P L A ++ SP + G + G DP TP ST S+ G G T XX XXXXXXXXXXXXXXXXXXXXXX PP PSFK GDLVSVPSRSSPGVNKEGGVAKVTL RP+GT DVKY+V GREKGV A I+S Y VDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX +S VRRT R KGWCSPD+AAGQA AACL+YMLG+TQHPELDLDPDLGELLDPNEG S XXXXXXXXXXXXXXXXXX G A+ D SD G SG E G + G KRK ARG + DD R RG + G GG SQG XXXXXXXXXXXXXXXXXXX VFDI+ +A +S D+ A A +DY+G G + A + S++ G G + RSR P A V SGK KGK+ G SG + GL +GRRG A AAA E + VVLT+SGST+E LA++L K LGW+VEPKYTEAVTHVVCGTV K AKA+VRS KFLR VA GKWVVTEAWLQEC+RR R +EEAFEV+GD+KS VPSAPTRSRLAHAD RPGLF GI+F FRGQFGTTGSPPLS+LE+MLL N G+VVST+ SL + A G XXXXXXXXXXXXXXXXXXXXXXXXX E ELS+Q S++ RGGG R G ++VV+PIWLVDSVGCFRVL P+V HR+P G
Sbjct: 1 MLPCNHPLCRGCASQCFKESQRCPQCMTPIPNLRMLQGRNKWIVHMVDKLKNSINDVGVSLTQHSPVPSKYRDNPSPKSGAAGKAAREXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--PTRRANAGASRGGAAAGGAFTEVAPTSSPWPNDDDGNGAIVPSAQLPPPPLPPQQPFVVGDLVLVESRTWPGMNKHGGVGLVVAVLDPPGSRYDVKYTVGNKTDRGIEARFVHAHAFPEETVGSRSRRGGAAGAGDTRARRRSGGRGGKS-GSVSPRGRSPVIGPAAAAAGGAKPTGSSRSGVVALDSTTAAALLPQRA---PSRTPICDGGG---AAEEDGPERDRAP------------------------------GVAAPVALAATXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHRDGADDEHGHNDA------REGSCHSDKA--SSENGGGEGLGEEDSENSHDIDDEIXXXXXXXXXXXYEDLDNTAPHPREKGGGDCEEDGRSQEEGEGKQVEGGDGSEANPVELLLSPPEREESEXXXXXRRKTDVGSSSDRAVPLSPP---ASITGGSTEETVPPLSPTSRQNLPWR----SRGGAAGPDGAGHRGRRDPPLXXXXXXXLSSDCGAGDPTT----LTSAAEGLVALASTGNRGGGSCTPPAGDVQEDAEEDSRMDDVGVDDHREGDTPTTTPVSHQAPRNPPSLGQTSSSGGHEFAPVRKGPPVSLAAAAATAPAALETAEALLSMSPSVRHGGGSLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRGACDDPVGTPNSTASLSRRLGPGSPSSATGLLRTTRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRPPATPSFKAGDLVSVPSRSSPGVNKEGGVAKVTLVRPNGTCDVKYIVHHGREKGVPAGIISFYAVDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSTPASKGAPSSSSRVRRTSR--KGWCSPDLAAGQAYAACLSYMLGETQHPELDLDPDLGELLDPNEGSSRAGSAGDGXXXXXXXXXXXXXXXXXXXXXXXXXXXG-AKEGDDGVTVVV---------------SDRGVGSSGGE------GGQGSVKGVVGKRKRIARGGGVDDDDTTRGDRGRNERQASDG---VEGGPSQGQGRRHXXXXXXXXXXXXXXXXXXX----VFDISASSAGSNSGDNGMALLTTAPPLDYEGRGGGDXXXXXXXXXXXXXXXXXXXXXAPLPAAAVDSNIHGGGXX-SGSRSRGRAAAPPTAAVRKRCRPSGSESAEVDGRPV----TSGKGKGKTVKAGRSXXXXXXXXXXXRSGVDGRGDXXGLQGACANGRRGLATSAAAVAEEDGAVVLTMSGSTSETSKLADSLAKRLGWQVEPKYTEAVTHVVCGTVPKTAKARVRSVKFLRAVAGGKWVVTEAWLQECRRRGCRAEEEAFEVTGDKKSHVPSAPTRSRLAHADVDRPGLFQGITFHFRGQFGTTGSPPLSDLESMLLANAGKVVSTLGSLCGARSTAVGSSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------XXXLAAETELSRQGSESAP--------RGGGGCGRDDGGVGVVVDVVRPIWLVDSVGCFRVLKPAVHHRVPGFG 1627
BLAST of mRNA_C-linearis_contig99.17181.1 vs. uniprot Match: D8LPM9_ECTSI (BRCT domain-containing protein n=1 Tax=Ectocarpus siliculosus TaxID=2880 RepID=D8LPM9_ECTSI)
Query: 2726 PKLPSFKVGDLVSVPSRSSPGVNKEGGVAKVTLARPDGTFDVKYMVRQGREKGVAAAILSPYKVDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---TSAVRRTPRSNKGWCSPDIAAGQANAACLNYMLGDTQHPELDLDPDLGELLDPNEGKSSXXXXXXXXXXXXXXXXXXXXXXXXXVKSTTGAPTGKARRQRDXXXXXXXXXXXXXXXXXLGGDSDDGKAVSGWEIRDSSDGRRRKNSGSGTKRKHPARGSVEESDDRKRLARGNGAEKRLSGDSHSRGGSSQGXXXXXXXXXXXXXXXXXXXXXXXXSKKDVFDITTLTADPDSEDDAAARRLVAAAVDYDGASGSSG--------------------LEVFDITALSPGSDVAGSGAPATKKRSRPSGGKEPARAAXXXXXXXXXXXXXXXXXXVGKKRRSGKDKGKSKAIGGKAGGS-------------RSRGGGASSGNEQEKVGLVSGRRGRAAAANPEAEKPVV-----LTLSGSTAEILTLANALVKSLGWRVEPKYTEAVTHVVCGTVQKNAKAKVRSAKFLRGVASGKWVVTEAWLQECKRRSGRVKEEAFEVSGDRKSAVPSAPTRSRLAHADPGRPGLFHGISFQFRGQFGTTGSPPLSELEAMLLDNGGRVVSTIESLFTS---PVGAGGXXXXXXXXXXXXXXXXXXXXXXXXXXXRPRRVVIFQPSSESPEEDARVLEED---LASVVEAELSKQTSKACTLAAEGARARGGGSGRRGAGPDNTAI--EVVKPIWLVDSVGCFRVLSPSVRHRLPSSG 5056
P PSFK GDLVSVPSRSSPGVNKEGGVAKVTL RPDGT DVKY+V GREKGV A I+S Y VDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX +S VRRT R KGWCSPD+AAGQA AACL+YMLG+TQHPELDLDPDLGELLDPNEG S XXXXXXXXXXXXX XXXXXXXXXXXXXXXXX E+++S D GG SQG XXXXXXXX +VFDI+ L+A +S D+ A +D +G G G V TA + G + RSR P A V SGK GKSK KAGGS R GGG +GRRG+A + LT+SGS++E+ LA++L KS GWRVEPKYTEAVTHVVCGTV K AKA+VRS KFLR VA GKWVVTEAWLQEC+RR R +EEAFEV+GD+KS VPSAPTRSRLAHAD RPGLF GI F FRGQFGTTGSPPLS+LE+MLL N G+VVST+ SL + P+G+G XXXXXXXXX RPR+VVIFQPSS P+ED R +EE A EAEL +Q S++ RGG R D + +VV+PIWLVDSVGCFRVL P+V HR+P G
Sbjct: 227 PATPSFKAGDLVSVPSRSSPGVNKEGGVAKVTLVRPDGTCDVKYIVHHGREKGVPAGIISFYAVDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLGSSSRSSTPASKEAPSSSRVRRTSR--KGWCSPDLAAGQAYAACLSYMLGETQHPELDLDPDLGELLDPNEGSSGAGSAGDGGGKVDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------------------XXXXXXXXXXXXXXXXXXXXRDERQVSDDVE--GGPSQGQGRXXXXXXXXISSSANEASEGM----EVFDISALSAGSNSGDNGMTLLTTAPPLDSEGRGGGGGDNHDXXXXXXXXXXXXXXXXXAVPLPTATVDFNSHGGXXXXXSGSRSRGRAAAPPTAAVRKRCRPPGSESAEVGGRPV----TSGK--GKSKTA--KAGGSXXXXXXXXXGVDGRGDGGGLQGA-------CANGRRGQATSXXXXXXXXXXXXXXXLTMSGSSSEMSKLADSLAKSRGWRVEPKYTEAVTHVVCGTVPKTAKARVRSVKFLRAVAGGKWVVTEAWLQECRRRGCRAEEEAFEVAGDKKSHVPSAPTRSRLAHADVDRPGLFQGIMFHFRGQFGTTGSPPLSDLESMLLANAGKVVSTLGSLCGARSIPLGSGSGXXXXXXXXXGW---------------RPRKVVIFQPSS--PDEDQRAMEEKKLAAALAAEAELLRQGSESAP--------RGGXXWGRDEDEDGVGVVVDVVRPIWLVDSVGCFRVLKPAVHHRVPGFG 986
BLAST of mRNA_C-linearis_contig99.17181.1 vs. uniprot Match: UPI001C71361F (BRCA1-associated RING domain protein 1-like n=1 Tax=Penaeus japonicus TaxID=27405 RepID=UPI001C71361F)
Query: 4175 EKPVVLTLSGSTAEILTLANALVKSLGWRVEPKYTEAVTHVVCGTVQKNAKAKVRSAKFLRGVASGKWVVTEAWLQECKRRSGRVKEEAFEVSGDRKSAVPSAPTRSRLAHADPGRPGLFHGISFQFRGQFGTTGSPPLSELEAMLLDNGGRVVS 4639
++ VVL G ++ + L K L R+ ++ VTHV+ Q A + R+ K++ VASGKW+++ W+++C + + E +EVSG +A AP ++R +A RPGLF+G G F +P E+E ++ GG +++
Sbjct: 380 QEKVVLLGYGLSSTLAKKVERLSKLLRARIVTDFSSDVTHVIAECAQDKAVCQ-RTLKYMMAVASGKWILSHRWMEDCVSQELALNPEEYEVSGSTHNANTKAPKQART-NAAKMRPGLFNGCHVFLWGNFREP-NPSKKEMEGLIKAGGGVILA 531
BLAST of mRNA_C-linearis_contig99.17181.1 vs. uniprot Match: UPI001FB7F409 (BRCA1-associated RING domain protein 1-like n=2 Tax=Penaeus TaxID=133894 RepID=UPI001FB7F409)
BLAST of mRNA_C-linearis_contig99.17181.1 vs. uniprot Match: UPI000F670FD8 (BRCA1-associated RING domain protein 1-like n=1 Tax=Penaeus vannamei TaxID=6689 RepID=UPI000F670FD8)
Query: 4187 VLTLSGSTAEILTLANALVKSLGWRVEPKYTEAVTHVVCGTVQKNAKAKVRSAKFLRGVASGKWVVTEAWLQECKRRSGRVKEEAFEVSGDRKSAVPSAP-------TRSRLAHADPGRPGLFHGISFQFRGQF 4567
VL L+G ++ A A+ ++G V K+ E+VTHV+ + +N + K + G+ASGKW+V+ AWL C + R EEAFE+ G S SAP RS + P L G + F GQF
Sbjct: 617 VLLLTGVPRDVEQRARAIADAMGATVLSKFDESVTHVLAA-LDENHLLISNTLKVMMGIASGKWIVSPAWLYACDTENRRANEEAFEMQGLASSPSESAPPVPPSSGARSSRLSSSP----LLTGFTIAFAGQF 745
BLAST of mRNA_C-linearis_contig99.17181.1 vs. uniprot Match: A0A1Z5JJV1_FISSO (Uncharacterized protein n=1 Tax=Fistulifera solaris TaxID=1519565 RepID=A0A1Z5JJV1_FISSO)
Query: 749 PFVVGDLVFVEHRTWPGMNKHGGVALVTAVLDPPGSRYDVKYTVGQKHDRGVEARYVRSYAFPDETV 949
PFV GD V VE RTWPG+N+ GG+ VT V + R V+Y VG++H++ + +YV+ Y+ P E +
Sbjct: 14 PFVEGDYVDVESRTWPGINQPGGIGQVTGVAE---DRVSVRYLVGRRHEKEIPIKYVKPYSIPSERL 77
Query: 4184 VVLTLSGSTAEILTLANALVKSLGWRVEPKYTEAVTHVVCG-------------TVQKNAKAKVRSAKFLRGVASGKWVVTEAWLQECKRRSGRVKEEAFEVSGDRK-SAVPSAPTRSRL--------AHADPGRPG--LFHGISFQFRGQFGTTGSPPLSELEAMLLDNGGRVVSTIESL 4654
+V SG + TL + + +G ++TE+VTHV+ + + N K+RS K+L+ V SG+W+V++AW+Q C + G V EE +EV G K VP ++RL A P G LF + G F + PP E+ +++ G +VS+++ L
Sbjct: 267 LVFLCSGLNHDEKTLVESCAQLVGATTVHEWTESVTHVIVKCQHAAPMRQKLQLSDKVNRWVKIRSIKYLKAVVSGRWIVSDAWIQACVKAKGLVSEETYEVQGLLKVQHVPEIAKKARLLRQANLATATGVPSAVGTRLFASLVCVVYGNFASP-LPPKHEIGSLVRLGDGTIVSSLDDL 446
BLAST of mRNA_C-linearis_contig99.17181.1 vs. uniprot Match: A0A1Z5K183_FISSO (Uncharacterized protein n=1 Tax=Fistulifera solaris TaxID=1519565 RepID=A0A1Z5K183_FISSO)
Query: 749 PFVVGDLVFVEHRTWPGMNKHGGVALVTAVLDPPGSRYDVKYTVGQKHDRGVEARYVRSYAFPDETV 949
PFV GD V VE RTWPG+N+ GG+ VT V + R V+Y VG++H++ + +YV+ Y+ P E +
Sbjct: 14 PFVEGDYVDVESRTWPGINQPGGIGQVTGVSE---DRVSVRYLVGRRHEKEILIKYVKPYSIPSERL 77
BLAST of mRNA_C-linearis_contig99.17181.1 vs. uniprot Match: A0A8J9YMT2_BRALA (BARD1 protein n=2 Tax=Branchiostoma lanceolatum TaxID=7740 RepID=A0A8J9YMT2_BRALA)
Query: 4184 VVLTLSGSTAEILTLANALVKS-----------LGWRVEPKYTEAVTHVVCGTVQKNAKAKVRSAKFLRGVASGKWVVTEAWLQECKRRSGRVKEEAFEVSGDRKSAVPSAPTRSRLAHADPGRPGLFHGISFQFRGQFGTTGSPPLSELEAMLLDNGGRVVS 4639
VV+T + ++++ LA L L +V + + VTH+V N R+ K+LRGV +GKW+V+ W+ C V E ++EV G + +R RL + + PGLF G F G+F +PP EL ++ GG +++
Sbjct: 823 VVMTTNNQVSQVVALATGLDSKQREALEQCMLVLDGKVVKTFDDQVTHLVAACDDTNRCP--RTIKYLRGVLTGKWIVSFKWVSACLEEQQHVPEGSYEVLGTLAKPSSTGASRGRL-NKEQQLPGLFDGCQFFLHGKFQPP-TPPRKELVELIRAGGGAILA 981
The following BLAST results are available for this feature:
E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Regulates centrosomal microtubule nucleation. Required for normal cell cycle progression from G2 to mitosis. Required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. Involved in transcriptional regulation of P21 in response to DNA damage. Required for FANCD2 targeting to sites of DNA damage. May function as a transcriptional regulator