EsuBft411_12 (polypeptide) Ectocarpus subulatus male Bft15b

Query:    1 MEYLAGRKVEVVVVGSVAMLAWVALSYYXXXRSSEAARVKNFVRSHASSDRSLPSPMPALPRWCGFIGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKPAEILQWKYLPVVTWVRETKQHSRRLEKVIQGAVNAVRADAKLADASLGDSAAEGDVGIGGTLLRKIIGATNGTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAPGQADPPEEFTSFTCGPKEFDMILTRAAKEE 561
            MEYLAGRKVEVVVVGSVAMLAWVALSYYXXXRSSEAARVKNFVRSH+SSD SLPSPMPALPRWCGFIGGHTLV + GE++ QLEGWAKEFGGDYELY+AGNKVTVV+GLSDIRRILTLRPS+FKRGIV NQTKWA+EQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADA EVVTSRDSFARFTHDIVALA FGVDVGAITATE+EPCPSFDAIERITSALI L+GKPAEIL+WKYLP+V WVRETKQHSRRLE VIQGAVNAVRADAKLADA+LGDSAAEGDVGIGGT+LRKIIGATNG+A+SSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTC EDFTMKSGRVLKKGTAVLTLNRA GISEDFFTR DEFVPERWI SERE ALSEK STWIGKGGI+HEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAPGQADPPEE++SFTCGPKEF+MILTR AK+E
Sbjct:    2 MEYLAGRKVEVVVVGSVAMLAWVALSYYXXXRSSEAARVKNFVRSHSSSDGSLPSPMPALPRWCGFIGGHTLVMQPGETVWQLEGWAKEFGGDYELYLAGNKVTVVSGLSDIRRILTLRPSKFKRGIVTNQTKWASEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAREVVTSRDSFARFTHDIVALAAFGVDVGAITATEEEPCPSFDAIERITSALISLMGKPAEILKWKYLPMVPWVRETKQHSRRLENVIQGAVNAVRADAKLADANLGDSAAEGDVGIGGTMLRKIIGATNGSANSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCTEDFTMKSGRVLKKGTAVLTLNRAVGISEDFFTRGDEFVPERWISSEREKALSEKQSTWIGKGGISHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAPGQADPPEEYSSFTCGPKEFNMILTRTAKDE 562          

Query:   15 GSVAMLAWVALSYYXXXRSSEAARVKNFVR--SHASSDRSLPSPMPALPRWCGFIGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGH-NVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKPAEILQWKYLP-VVTWVRETKQHSRRLEKVIQGAVNAVRADAKLADASLGDSAAEGDVGIGGTLLRKII----GATNGTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAPGQADPPEEFTSFTCGPKEFDMILTR 556
            G+++++   AL+YY   R SE +R +   +    A+   SLPSP+  LPRW  F+GGHTL     + M Q+EGWA + GGDYE+ + G +V  VT   DIRRIL LRPS+FKRG       W    VGV  SLFFEEGK WGRSRRLI+P L+GH NVA M+P IAK+ ER C KLGD    GE V     F R+THD +AL+ FG D  ++ AT+  P  SF+A+  I  A + L   P  +L W  L  ++ WVRE K+ S RL++V++GA++  R++ K A AS      EG       LLRK++    G+ N     S+RM  +++E++ Q+ GLF+A +ETTA TL W +Y+L K+P+  LRCR EAL+ AP     +  A        C A  + +               E  TMKSG  L+ GTA   L R   +SE  FTRA +FVPERWI +ERE AL  +P+       + H EE   + G GPR CPG DMA  E AII+AAI ARFDL+LAPGQADPPEE   FT G +   ++LT+
Sbjct:   18 GTLSLVVVSALTYYVCWRWSETSRARRVAKLGRSAAGSSSLPSPVAVLPRWIPFVGGHTLQMESEKMMQQVEGWADDLGGDYEITLIGKRVIFVTDPEDIRRILLLRPSKFKRG-------W--RPVGVYPSLFFEEGKEWGRSRRLIAPFLSGHKNVAGMVPSIAKIAERVCAKLGD--GQGEPVDFVQEFGRYTHDAIALSGFGFDADSVRATKDRPSVSFEAMGAIVEAALALSVDPLAMLAWSTLSSLLPWVREIKEKSSRLQRVVEGAIDKTRSEMKEAGASHPAGGEEG------ALLRKLLSVEGGSDNAIKDVSNRMTLSDKEIVTQSKGLFLAGSETTAKTLSWAVYFLAKHPEMHLRCREEALRAAPLRTANIERA--------CIATTRRS--------------QETTTMKSGLKLEAGTAFTLLLRYPCLSEHSFTRAKDFVPERWIDAEREEALLGQPADRKSSD-VVHREEVAQAFGGGPRKCPGMDMAHLEAAIILAAISARFDLALAPGQADPPEEVFKFTAGVESLKLVLTK 527          

Query:   54 PSPMPALPRWCGF-IGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKPAEILQWKYLPVVTWVRETKQHSRRLEKVIQGA---VNAVRADAKL---ADASLGDSAAEGDVGIGGTLLRKIIGATNGTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAPGQADPPEEFTSFTCGPKEFDMILTRAAKE 560
            P P+ ALP   G+ + G+     R +    LE WA+++G  Y+L     ++ V++ +   RR+L  RP  F+R     +       +G+ +SLF  EG+TW R RR+    LN H++A  LP +  +  R        ADAG+ VT  D   R+T D+     FG D  A+   E       D I++  S ++ ++ + A I      PV  W     +  R+L+  ++G    +  + ADA+    AD SL +            L+  ++          D  +F++ ++   A G  VA  +TTA+TL W MY+L  +P+A  R  AE   VA  SD             F  AV  E  RL+  AP        +  +  G  +  GT ++   R     +  F    EF PERW+  +  N ++  P                L  GHGPR+CPG+++A+ E   + A +   F +S A  +  P EE  +FT  PKE  +   R A E
Sbjct:    8 PKPLSALPGPRGWPLLGNLPQLSRTQMHLVLERWAQQYGPLYQLRFLNKRLMVISDIELCRRVLRERPENFRRFPAFERI---IGDMGL-TSLFSSEGETWRRQRRVFMRALNIHHMAPFLPKLEVITGRLRSLWQRAADAGQPVTVLDDVMRYTLDVTTRFAFGYDANALETHE-------DPIQKHLSRILPMVSRRARI------PVPYWRWIKFKADRQLDADLEGVRGYIEGLIADARARIAADPSLKEKPTN--------LIEALL-----VTGDEDGSVFSDHDIFSNALGTLVAGEDTTAMTLAWMMYFLAGHPEAQERLHAEV--VAGGSD-----------YPFLEAVMNETFRLKPVAPVFFLHATANVEL-GGYAVPAGTDLVLATRPGAYDDAEFPDGREFRPERWLVPQA-NYVTRAP----------------LPFGHGPRLCPGRNLAQLEIRTVAAMLARDFRISRADDK--PVEESFAFTMAPKELQVRFERRAGE 458          

Query:   54 PSPMPALPRWCGF-IGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKPAEILQWKYLPVVTWVRETKQHSRRLEKV---IQGAVNAVRADAKL---ADASLGDSAAEGDVGIGGTLLRKIIGATNGTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAPGQADPPEEFTSFTCGPKEFDMILTR 556
            P P+ ALP   G+ + G+     +G     LE W  E G  Y L      V V+  +   RR+L  RP  F R    ++       +G+ +SLF  EG+TW R RR+    LN H +A  +P +  +  R  G     A AG+ V   D   R+T D+     FG D  A+   E       D I++  S ++  + + A I      PV  W     +  R+L+     ++G +  + A+A+    AD +L +           T L + + AT       D  +F++ ++   A G  VA  +TTA+TL W MY+L +NP A  R  AEA++   E               +  AV  E  RL+  AP        D  +  G  +  GT ++ + R A      F     F PERW        LS +PS         +   A L+ GHGPR+CPG+++A+ E   +   +   F +SL P Q  P EE+ +FT  PKE  +   R
Sbjct:    8 PKPLDALPGPRGWPLLGNLPQLGQGRMHQVLERWVHEHGPLYRLRFVNKPVMVIADIELCRRVLRERPENFGRFPAFHRI---ISDMGL-TSLFSSEGETWRRQRRVFMRALNIHQMAPFMPRLDAITARLQGLWVRAAGAGQPVAVLDDIMRYTLDVTTRFAFGYDANALETHE-------DPIQKHLSRILPQVSRRARI------PVPYWRWFKLKADRQLDADLAGVRGYIEGLIAEARARIAADPALAERP---------TNLIEALLATR----DEDGSVFSDHDIFSNALGTLVAGEDTTAMTLAWMMYFLAQNPGAQERLHAEAMQGGAERP-------------YLDAVMSETFRLKPVAPVFFLHANVDVEL-GGYAVPAGTDLVLVTRPAANDTAEFPGEPGFHPERW--------LSPQPS---------YITRAPLAFGHGPRLCPGRNLAQLEIRAVATMLAREFRISL-PDQR-PVEEYFAFTMAPKELRLRFDR 454          

Query:   48 SSDRSLPSPMPALPRWCGFIGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIR-RILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSF-DAIERITSALIGLIGKPAEILQWKYLPVVTWVRETK--QHS-RRLEKVIQGAVNAVRADAKLADASLGDSAAEGDVGIGGTLLRKIIGATNGTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEE--EAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAPGQADPPEEFTSFTCGP 547
            +S + LPSP   +      I G+   F+       LE WAKE G  Y++ +AG K+ VV+   D+   IL LRP  F+R   +++      ++G+ + +F  EG+ W R R++ S  LN  NV +  P I +  +    K    A+A E V  +     +T DI     FG  + +I    +    +F + +ERI   +   I  P  +  W+    +   +E+K   HS   ++K+I   ++  ++    +++   + +           L  I+         S+R  F++ E+      + +A  +TT+ ++ W +YYL ++P+   R R EA +V  ++D +        +L+F  AV +EA+R++   P+L     ED  +    V  K T V+  ++ A  S+D+FT A  F P+RW+R               GK  + H+   +   + G GPR CPG ++A  E  ++I+A+C RFD  LA    D  ++F +FT  P
Sbjct:    8 TSIKDLPSPKGKI------ILGNLPEFKTENKHLVLEEWAKECGDLYKISLAG-KIFVVSAKPDLNAEILKLRPKEFRRFGKIDEI---FTELGI-TGVFNAEGERWKRHRKITSEALNAQNVKSFYPTILEKTDILLSKFSTYAEAKEKVAVQSEMMAYTVDITTKIAFGYQMNSI----ENVADNFQEHLERIFPMINQRITAPLPL--WR----IVKSKESKALDHSLSEIKKLIYTFIDEAKSRLDNSESLKANPS---------NFLEAIL-------VESERETFSKEEIYGNVFTMLLAGEDTTSNSISWAIYYLAQHPEIVKRIRDEAKEVYGDTD-LPQEYSSFAKLKFSNAVAQEAIRIKPTTPQLYMQANEDVIVGQLSV-PKATIVVLQSKIAQNSDDYFTNALTFNPDRWMR---------------GKCPVDHKHSPKVVKAFGGGPRYCPGMNLAMHEMTVLISALCKRFDFELAVKAEDVKDKF-AFTMHP 459          

Query:   67 IGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGER---FCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKPAEILQW-KYLPVVTWVRETKQHSRRLEKVIQGAVNAVRADAKLADASLGDSAAEGDVGIGGTLLRKIIGATNGTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEE-EAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAPGQADPPEEFTSFTCGPKEFDM 552
            I GH     +     Q E WAKE+G  Y L      VTV T       I   RP++F+R     +      +VGV   +F  EG++W + R++    L+  NV A  P I  V +R   +      K D  +   S+D F R T D+     FG D+  +   E +   + + +E+I   L   +  P  + ++ K   V  +    K     L K I  A   ++ D  L +                  L  ++      AS      F   E+      + +A  +TT+ +L W  Y+L+K P+   + R E  +V  E+ G + + EQ+++ ++ +AVFKE  RL+   P L   C+ED T+ +  +  KG  ++T   +A  SE++F +A EF+PERW++        EK    +G     H++ +A    G GPR+CPG+ +A+ E  + +  +   F++       +  EE  +FT   K   +
Sbjct:   21 IVGHIFDLEKDRLHLQYEDWAKEYGELYNLKFLNINVTVSTNPDTNAYIFKNRPNKFRR---FKKLADVINEVGVDG-VFTAEGESWKKQRKVTQKALDNKNVKAFFPSILTVADRLKNYWDTQVSKGDQLDYPLSKD-FIRATVDVTTNLAFGYDMNTV---ENQTNDTQEHVEKIFPQLNKRVNSPIPLYKYFKTAEVKDFEESLKYIREHLGKFITQAEERLKNDPSLYENP-------------SNFLEAML------ASQDKDDPFTWDEIFGNLYTMLLAGEDTTSNSLTWTSYFLSKYPEVQEKIREEIRQVLGEN-GKIKSFEQIQQFQYTSAVFKEVTRLKPVTPNLYMQCLED-TVVNDVLFPKGHFIITQLSSAARSEEYFEKAKEFIPERWLK--------EKDEPVVGCPFHGHKKADAMKPFGGGPRLCPGKFLAEVESVVFLVTLMKDFEIEFYDKDLEV-EELFAFTMQAKNLKL 473          

Query:   51 RSLPSPMPALPRWCGFIGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKPAEILQWKYLPVVTWVRETKQHSRRLE---KVIQGAVNAVRADAKLADASLGDSAAEGDVGIGGTLLRKIIGATN--GTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDL 527
            R LP P    P+W   + G+TL  +  +    +E W +++G    + + G  + VV+    I  +L  RP  F+R   + Q      ++G+Q  +F  EG+ W + RR++  +     V A LP + KV  R  G+    A  G  +  +    RFT D ++   FG+DV  I + +       D I+R    +   I + A  +    +P   W +  +   RRL+   KV+  A+    ADA+L        AA  +      LL  +I A +  G+  S D +  N   ++       +A  +TTA +L W +Y +++ P+   R R E        D    TA+ L RL +  A   E++RL+   P      ++D T+     ++ GT+VL L R   + E+ F +A+ F+PERW+    + A    P          H +   +  G GPRICPG+ +A  E  ++ A +   FD+
Sbjct:    2 RDLPGP----PQWP--LVGNTLQVQLDKVHQDVEKWVQQYGPMLHVRLGGFPLLVVSDHELIATLLRDRPDTFRRPSRMQQIM---SEMGIQDGVFVAEGEHWAKQRRMVMASFAPGQVRAYLPALLKVAARLRGRFERAAARGTPIELQADLMRFTVDAISGLAFGMDVNTIESND-------DVIQRHLDQIFPTIWRRAHAI----VPYWKWFKLPRD--RRLDRSVKVVNTAIRGYIADARLRLQDQARRAAPHN------LLEAMIVAADEPGSGMSDDDVAGNVFTML-------LAGEDTTATSLSWMLYLMSREPQTLQRARQEVEHCL--GDLQAWTADDLGRLDYLEACIHESMRLKPVGPFNVVEALKD-TVVGDVQIRAGTSVLLLMRHDTVREEAFPQAERFMPERWL----DEATHLAPQ---------HAKRVSMPFGAGPRICPGRYLALLEIKLVAAMLLQHFDI 432          

Query:   51 RSLPSPMPALPRWCGFIGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKPAEIL--QWKYLPVVTWVRETKQHSRRLEKVIQGAVNAVRADAKLADASLGDSAAEGDVGIGGTLLRKIIGATN--GTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDL-SLAPGQADPPEEFTSFTCGPKEFDMILTR 556
            R LP P    P+W   + G+ L  +  +    +E W K +G    + + G  + VV+    I  +L  RP  F+R    ++ +    ++G+Q  +F  EG+ W + RR++  +     V A LP + KV  R   +    A  G+ +  +    RFT D ++   FG+DV  I + +       D I+R    +   I + +  +   WK+  +           RRL++ ++    A+R     A   L D A          LL  +I A +  G+  S D ++ N   ++       +A  +TTA +L W +Y +++NP    R R E      + +    TA+ L RL +  A   E++R++   P      ++D T+     ++ GT+V+ + R   +S+D F +A  F+PERW+    + A    P          H +   +  G GPRICPG+ +A  E  ++ A +   FD+ S+        +E  + T  P    M + R
Sbjct:   27 RDLPGP----PQWP--VVGNALQVQLSKVHQNVEAWVKRYGPMIHVRLGGFPLLVVSDHEVIASLLRDRPEGFRRP---SRMQEIMAEMGIQDGVFVAEGEHWAKQRRMVMASFAPGQVRAYLPALLKVAGRLRDRFELAAQQGQAIDLQADLMRFTVDAISGLAFGMDVNTIESDD-------DVIQRHLDQIFPTIWRRSHAIVRYWKWFKL--------PRDRRLDRSVKAVNVAIRGFMAQARVRLQDPARRAAPH---NLLEAMIVAADEPGSGMSDDDVVGNVFTML-------LAGEDTTATSLSWMIYLMSRNPHTLQRARQEVDSCLGDLNNW--TADDLGRLDYLEACIHESMRIKPVGPFNVVQALKD-TVVGDVQIRAGTSVVMVMRHDTLSDDTFPQAQRFMPERWL----DEATQLAPH---------HAKRVSMPFGAGPRICPGRYLALLEIKLVAAMLLQHFDIVSVDTPDGRDADEHMALTMVPVGLKMRIRR 487          

Query:   67 IGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKP--AEILQWKYLPVVTWVRETKQHSRRLEKVIQGAVNAVRADAKLA-DASLGDSAAEGDVGIGGTLLRKIIGATNGTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDL---SLAPGQADPPEEFTSFTCGPKEFDMIL 554
            + G+ L         Q+E W +++G  ++L +   ++ VV     I  +L  RP  F+R     + +    + G+ + LF   G+TW R RR++    +  +V    P + +V  R  G+    A AG  +  +    RFT D VA   FG DV  + + E       D I+R  + +   + K   A +  W++ P     R   +    +   +QG +   +A ++LA D +L +          G LL  ++ A +  AS  D     + ++     GL +A  +TTA TL W ++ L+++P+   R RAE   V    D ++   EQL RL F  A   E +RLR   P L+F      T      +  G  V+ + R   +SE     A  F PERW    ++   +++ S               +  G GPRICPG+ +A  E  +  A +   F+L       GQA  P E    + GP    M L
Sbjct:   26 VFGNLLQIDSTRVHQQVEAWCEDYGPLFKLRLGKRRIVVVGDHELIAAVLRDRPEGFRR---TQKLEDIGREAGLGAGLFAVNGETWKRQRRMVMAGFDPVHVRRYYPALLRVAGRLVGRWQAAARAGRSIELQADLMRFTVDAVAGLAFGEDVNTLQSDE-------DVIQRHLNRIFPTLFKRIFAPLPTWRWWPSAE-DRALTRSVAEINVAVQGFI--AKARSRLAADPALREKP--------GNLLEAMLVAADTPASGID-----DEQVAGNVLGLLLAGEDTTANTLAWMIWLLSRHPQMLARARAEVDGVL--GDAVLPDLEQLGRLDFVEACAHETMRLRPVGP-LNFAQAVHDTRVGDVAVPAGMVVMAVMRRDAVSERHLHDAAAFDPERWAHDAKQAGAAKRLS---------------MPFGAGPRICPGRYLALMEIKLACAVLLRNFELVAVDTPDGQA--PREHLQLSMGPVGLSMRL 473          

Query:   67 IGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKPAEILQWKYLPVVTWVRETKQHSRRLEKVIQGAVNAVRADAKLADASLGDSAAEGDVGIGGTLLRKIIGATNGTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAP---GQADPPEEFTSFTCGPKEFDMIL 554
            + G+ L         Q+E W + FG  ++L +   +V VV     I  +L  RP  F+R     + +    ++G+   LF   G+ W R RR++    +  +V    P + +V ER  G+    A     +  +    RFT D VA   FG DV  + + E       D I++  + +  ++ K        + P+ TW    +   R L   +     AV+     A A L  SA  G     G LL  ++ A +   S  D     + ++      + +A  +TTA TL W ++ L+++P+A  + RAE  +V    D  +    QL +L F  A   E +RLR  AP  +   + D T      +  GT V+ + R   +SE     A  F P+RW+   ++  ++++ S               +  G GPRICPG+ +A  E  + +AA+   FD++      GQA  P E      GP    M L
Sbjct:   26 VFGNLLQIDSTRVHQQVEAWCEAFGPVFKLRLGKRRVVVVGDHELITAVLRDRPDGFRR---TQRLEEVGREMGLVGGLFSVNGEVWKRQRRMVMAGFDPVHVKRYYPALLRVAERLVGRWQRAARQDRRIELQADLMRFTVDAVAGLAFGEDVNTLQSDE-------DVIQQHLNRIFPMLFKRM------FSPLPTWRWWPRGEDRALAHSVAAIDVAVQGFIAQARARL--SADPGLRSAPGNLLEAMLVAADEPGSGID-----DAQVAGNVLTMLLAGEDTTANTLAWMIWLLSRHPEALAQARAEVDRVL--GDAALPDLAQLGQLDFVEACAHETMRLRPVAPINTMQAVHD-TRVGDVAVPAGTLVMGVMRHDAVSERHLPGAAAFDPQRWLGDAKQAGVAKRLS---------------MPFGAGPRICPGRYLALMEIKLAMAALLRHFDIAAVDTPDGQA--PREHLQLAMGPVGLSMRL 473          

Query:  543 MEYLAGRKVEVVVVGSVAMLAWVALSYYXXXRSSEAARVKNFVRSHASSDRSLPSPMPALPRWCGFIGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKPAEILQWKYLPVVTWVRETKQHSRRLEKVIQGAVNAVRADAKLADASLGDSAAEGDVGIGGTLLRKIIGATNGTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAPGQADPPEEFTSFTCGPKEFDMILTRAAKEE 2225
            MEYLAGRKVEVVVVGSVAMLAWVALSYYXXXRSSEAARVKNFVRSH+SSD SLPSPMPALPRWCGFIGGHTLV + GE++ QLEGWAKEFGGDYELY+AGNKVTVV+GLSDIRRILTLRPS+FKRGIV NQTKWA+EQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADA EVVTSRDSFARFTHDIVALA FGVDVGAITATE+EPCPSFDAIERITSALI L+GKPAEIL+WKYLP+V WVRETKQHSRRLE VIQGAVNAVRADAKLADA+LGDSAAEGDVGIGGT+LRKIIGATNG+A+SSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTC EDFTMKSGRVLKKGTAVLTLNRA GISEDFFTR DEFVPERWI SERE ALSEK STWIGKGGI+HEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAPGQADPPEE++SFTCGPKEF+MILTR AK+E
Sbjct:    2 MEYLAGRKVEVVVVGSVAMLAWVALSYYXXXRSSEAARVKNFVRSHSSSDGSLPSPMPALPRWCGFIGGHTLVMQPGETVWQLEGWAKEFGGDYELYLAGNKVTVVSGLSDIRRILTLRPSKFKRGIVTNQTKWASEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAREVVTSRDSFARFTHDIVALAAFGVDVGAITATEEEPCPSFDAIERITSALISLMGKPAEILKWKYLPMVPWVRETKQHSRRLENVIQGAVNAVRADAKLADANLGDSAAEGDVGIGGTMLRKIIGATNGSANSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCTEDFTMKSGRVLKKGTAVLTLNRAVGISEDFFTRGDEFVPERWISSEREKALSEKQSTWIGKGGISHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAPGQADPPEEYSSFTCGPKEFNMILTRTAKDE 562          

Query:  585 GSVAMLAWVALSYYXXXRSSEAARVKNFVR--SHASSDRSLPSPMPALPRWCGFIGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGH-NVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKPAEILQWKYLP-VVTWVRETKQHSRRLEKVIQGAVNAVRADAKLADASLGDSAAEGDVGIGGTLLRKII----GATNGTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAPGQADPPEEFTSFTCGPKEFDMILTR 2210
            G+++++   AL+YY   R SE +R +   +    A+   SLPSP+  LPRW  F+GGHTL     + M Q+EGWA + GGDYE+ + G +V  VT   DIRRIL LRPS+FKRG       W    VGV  SLFFEEGK WGRSRRLI+P L+GH NVA M+P IAK+ ER C KLGD    GE V     F R+THD +AL+ FG D  ++ AT+  P  SF+A+  I  A + L   P  +L W  L  ++ WVRE K+ S RL++V++GA++  R++ K A AS      EG       LLRK++    G+ N     S+RM  +++E++ Q+ GLF+A +ETTA TL W +Y+L K+P+  LRCR EAL+ AP     +  A        C A  + +               E  TMKSG  L+ GTA   L R   +SE  FTRA +FVPERWI +ERE AL  +P+       + H EE   + G GPR CPG DMA  E AII+AAI ARFDL+LAPGQADPPEE   FT G +   ++LT+
Sbjct:   18 GTLSLVVVSALTYYVCWRWSETSRARRVAKLGRSAAGSSSLPSPVAVLPRWIPFVGGHTLQMESEKMMQQVEGWADDLGGDYEITLIGKRVIFVTDPEDIRRILLLRPSKFKRG-------W--RPVGVYPSLFFEEGKEWGRSRRLIAPFLSGHKNVAGMVPSIAKIAERVCAKLGD--GQGEPVDFVQEFGRYTHDAIALSGFGFDADSVRATKDRPSVSFEAMGAIVEAALALSVDPLAMLAWSTLSSLLPWVREIKEKSSRLQRVVEGAIDKTRSEMKEAGASHPAGGEEG------ALLRKLLSVEGGSDNAIKDVSNRMTLSDKEIVTQSKGLFLAGSETTAKTLSWAVYFLAKHPEMHLRCREEALRAAPLRTANIERA--------CIATTRRS--------------QETTTMKSGLKLEAGTAFTLLLRYPCLSEHSFTRAKDFVPERWIDAEREEALLGQPADRKSSD-VVHREEVAQAFGGGPRKCPGMDMAHLEAAIILAAISARFDLALAPGQADPPEEVFKFTAGVESLKLVLTK 527          

Query:  702 PSPMPALPRWCGF-IGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKPAEILQWKYLPVVTWVRETKQHSRRLEKVIQGA---VNAVRADAKL---ADASLGDSAAEGDVGIGGTLLRKIIGATNGTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAPGQADPPEEFTSFTCGPKEFDMILTRAAKE 2222
            P P+ ALP   G+ + G+     R +    LE WA+++G  Y+L     ++ V++ +   RR+L  RP  F+R     +       +G+ +SLF  EG+TW R RR+    LN H++A  LP +  +  R        ADAG+ VT  D   R+T D+     FG D  A+   E       D I++  S ++ ++ + A I      PV  W     +  R+L+  ++G    +  + ADA+    AD SL +            L+  ++          D  +F++ ++   A G  VA  +TTA+TL W MY+L  +P+A  R  AE   VA  SD             F  AV  E  RL+  AP        +  +  G  +  GT ++   R     +  F    EF PERW+  +  N ++  P                L  GHGPR+CPG+++A+ E   + A +   F +S A  +  P EE  +FT  PKE  +   R A E
Sbjct:    8 PKPLSALPGPRGWPLLGNLPQLSRTQMHLVLERWAQQYGPLYQLRFLNKRLMVISDIELCRRVLRERPENFRRFPAFERI---IGDMGL-TSLFSSEGETWRRQRRVFMRALNIHHMAPFLPKLEVITGRLRSLWQRAADAGQPVTVLDDVMRYTLDVTTRFAFGYDANALETHE-------DPIQKHLSRILPMVSRRARI------PVPYWRWIKFKADRQLDADLEGVRGYIEGLIADARARIAADPSLKEKPTN--------LIEALL-----VTGDEDGSVFSDHDIFSNALGTLVAGEDTTAMTLAWMMYFLAGHPEAQERLHAEV--VAGGSD-----------YPFLEAVMNETFRLKPVAPVFFLHATANVEL-GGYAVPAGTDLVLATRPGAYDDAEFPDGREFRPERWLVPQA-NYVTRAP----------------LPFGHGPRLCPGRNLAQLEIRTVAAMLARDFRISRADDK--PVEESFAFTMAPKELQVRFERRAGE 458          

Query:  702 PSPMPALPRWCGF-IGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKPAEILQWKYLPVVTWVRETKQHSRRLEKV---IQGAVNAVRADAKL---ADASLGDSAAEGDVGIGGTLLRKIIGATNGTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAPGQADPPEEFTSFTCGPKEFDMILTR 2210
            P P+ ALP   G+ + G+     +G     LE W  E G  Y L      V V+  +   RR+L  RP  F R    ++       +G+ +SLF  EG+TW R RR+    LN H +A  +P +  +  R  G     A AG+ V   D   R+T D+     FG D  A+   E       D I++  S ++  + + A I      PV  W     +  R+L+     ++G +  + A+A+    AD +L +           T L + + AT       D  +F++ ++   A G  VA  +TTA+TL W MY+L +NP A  R  AEA++   E               +  AV  E  RL+  AP        D  +  G  +  GT ++ + R A      F     F PERW        LS +PS         +   A L+ GHGPR+CPG+++A+ E   +   +   F +SL P Q  P EE+ +FT  PKE  +   R
Sbjct:    8 PKPLDALPGPRGWPLLGNLPQLGQGRMHQVLERWVHEHGPLYRLRFVNKPVMVIADIELCRRVLRERPENFGRFPAFHRI---ISDMGL-TSLFSSEGETWRRQRRVFMRALNIHQMAPFMPRLDAITARLQGLWVRAAGAGQPVAVLDDIMRYTLDVTTRFAFGYDANALETHE-------DPIQKHLSRILPQVSRRARI------PVPYWRWFKLKADRQLDADLAGVRGYIEGLIAEARARIAADPALAERP---------TNLIEALLATR----DEDGSVFSDHDIFSNALGTLVAGEDTTAMTLAWMMYFLAQNPGAQERLHAEAMQGGAERP-------------YLDAVMSETFRLKPVAPVFFLHANVDVEL-GGYAVPAGTDLVLVTRPAANDTAEFPGEPGFHPERW--------LSPQPS---------YITRAPLAFGHGPRLCPGRNLAQLEIRAVATMLAREFRISL-PDQR-PVEEYFAFTMAPKELRLRFDR 454          

Query:  684 SSDRSLPSPMPALPRWCGFIGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIR-RILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSF-DAIERITSALIGLIGKPAEILQWKYLPVVTWVRETK--QHS-RRLEKVIQGAVNAVRADAKLADASLGDSAAEGDVGIGGTLLRKIIGATNGTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEE--EAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAPGQADPPEEFTSFTCGP 2183
            +S + LPSP   +      I G+   F+       LE WAKE G  Y++ +AG K+ VV+   D+   IL LRP  F+R   +++      ++G+ + +F  EG+ W R R++ S  LN  NV +  P I +  +    K    A+A E V  +     +T DI     FG  + +I    +    +F + +ERI   +   I  P  +  W+    +   +E+K   HS   ++K+I   ++  ++    +++   + +           L  I+         S+R  F++ E+      + +A  +TT+ ++ W +YYL ++P+   R R EA +V  ++D +        +L+F  AV +EA+R++   P+L     ED  +    V  K T V+  ++ A  S+D+FT A  F P+RW+R               GK  + H+   +   + G GPR CPG ++A  E  ++I+A+C RFD  LA    D  ++F +FT  P
Sbjct:    8 TSIKDLPSPKGKI------ILGNLPEFKTENKHLVLEEWAKECGDLYKISLAG-KIFVVSAKPDLNAEILKLRPKEFRRFGKIDEI---FTELGI-TGVFNAEGERWKRHRKITSEALNAQNVKSFYPTILEKTDILLSKFSTYAEAKEKVAVQSEMMAYTVDITTKIAFGYQMNSI----ENVADNFQEHLERIFPMINQRITAPLPL--WR----IVKSKESKALDHSLSEIKKLIYTFIDEAKSRLDNSESLKANPS---------NFLEAIL-------VESERETFSKEEIYGNVFTMLLAGEDTTSNSISWAIYYLAQHPEIVKRIRDEAKEVYGDTD-LPQEYSSFAKLKFSNAVAQEAIRIKPTTPQLYMQANEDVIVGQLSV-PKATIVVLQSKIAQNSDDYFTNALTFNPDRWMR---------------GKCPVDHKHSPKVVKAFGGGPRYCPGMNLAMHEMTVLISALCKRFDFELAVKAEDVKDKF-AFTMHP 459          

Query:  741 IGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGER---FCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKPAEILQW-KYLPVVTWVRETKQHSRRLEKVIQGAVNAVRADAKLADASLGDSAAEGDVGIGGTLLRKIIGATNGTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEE-EAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAPGQADPPEEFTSFTCGPKEFDM 2198
            I GH     +     Q E WAKE+G  Y L      VTV T       I   RP++F+R     +      +VGV   +F  EG++W + R++    L+  NV A  P I  V +R   +      K D  +   S+D F R T D+     FG D+  +   E +   + + +E+I   L   +  P  + ++ K   V  +    K     L K I  A   ++ D  L +                  L  ++      AS      F   E+      + +A  +TT+ +L W  Y+L+K P+   + R E  +V  E+ G + + EQ+++ ++ +AVFKE  RL+   P L   C+ED T+ +  +  KG  ++T   +A  SE++F +A EF+PERW++        EK    +G     H++ +A    G GPR+CPG+ +A+ E  + +  +   F++       +  EE  +FT   K   +
Sbjct:   21 IVGHIFDLEKDRLHLQYEDWAKEYGELYNLKFLNINVTVSTNPDTNAYIFKNRPNKFRR---FKKLADVINEVGVDG-VFTAEGESWKKQRKVTQKALDNKNVKAFFPSILTVADRLKNYWDTQVSKGDQLDYPLSKD-FIRATVDVTTNLAFGYDMNTV---ENQTNDTQEHVEKIFPQLNKRVNSPIPLYKYFKTAEVKDFEESLKYIREHLGKFITQAEERLKNDPSLYENP-------------SNFLEAML------ASQDKDDPFTWDEIFGNLYTMLLAGEDTTSNSLTWTSYFLSKYPEVQEKIREEIRQVLGEN-GKIKSFEQIQQFQYTSAVFKEVTRLKPVTPNLYMQCLED-TVVNDVLFPKGHFIITQLSSAARSEEYFEKAKEFIPERWLK--------EKDEPVVGCPFHGHKKADAMKPFGGGPRLCPGKFLAEVESVVFLVTLMKDFEIEFYDKDLEV-EELFAFTMQAKNLKL 473          

Query:  693 RSLPSPMPALPRWCGFIGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKPAEILQWKYLPVVTWVRETKQHSRRLE---KVIQGAVNAVRADAKLADASLGDSAAEGDVGIGGTLLRKIIGATN--GTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDL 2123
            R LP P    P+W   + G+TL  +  +    +E W +++G    + + G  + VV+    I  +L  RP  F+R   + Q      ++G+Q  +F  EG+ W + RR++  +     V A LP + KV  R  G+    A  G  +  +    RFT D ++   FG+DV  I + +       D I+R    +   I + A  +    +P   W +  +   RRL+   KV+  A+    ADA+L        AA  +      LL  +I A +  G+  S D +  N   ++       +A  +TTA +L W +Y +++ P+   R R E        D    TA+ L RL +  A   E++RL+   P      ++D T+     ++ GT+VL L R   + E+ F +A+ F+PERW+    + A    P          H +   +  G GPRICPG+ +A  E  ++ A +   FD+
Sbjct:    2 RDLPGP----PQWP--LVGNTLQVQLDKVHQDVEKWVQQYGPMLHVRLGGFPLLVVSDHELIATLLRDRPDTFRRPSRMQQIM---SEMGIQDGVFVAEGEHWAKQRRMVMASFAPGQVRAYLPALLKVAARLRGRFERAAARGTPIELQADLMRFTVDAISGLAFGMDVNTIESND-------DVIQRHLDQIFPTIWRRAHAI----VPYWKWFKLPRD--RRLDRSVKVVNTAIRGYIADARLRLQDQARRAAPHN------LLEAMIVAADEPGSGMSDDDVAGNVFTML-------LAGEDTTATSLSWMLYLMSREPQTLQRARQEVEHCL--GDLQAWTADDLGRLDYLEACIHESMRLKPVGPFNVVEALKD-TVVGDVQIRAGTSVLLLMRHDTVREEAFPQAERFMPERWL----DEATHLAPQ---------HAKRVSMPFGAGPRICPGRYLALLEIKLVAAMLLQHFDI 432          

Query:  693 RSLPSPMPALPRWCGFIGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKPAEIL--QWKYLPVVTWVRETKQHSRRLEKVIQGAVNAVRADAKLADASLGDSAAEGDVGIGGTLLRKIIGATN--GTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDL-SLAPGQADPPEEFTSFTCGPKEFDMILTR 2210
            R LP P    P+W   + G+ L  +  +    +E W K +G    + + G  + VV+    I  +L  RP  F+R    ++ +    ++G+Q  +F  EG+ W + RR++  +     V A LP + KV  R   +    A  G+ +  +    RFT D ++   FG+DV  I + +       D I+R    +   I + +  +   WK+  +           RRL++ ++    A+R     A   L D A          LL  +I A +  G+  S D ++ N   ++       +A  +TTA +L W +Y +++NP    R R E      + +    TA+ L RL +  A   E++R++   P      ++D T+     ++ GT+V+ + R   +S+D F +A  F+PERW+    + A    P          H +   +  G GPRICPG+ +A  E  ++ A +   FD+ S+        +E  + T  P    M + R
Sbjct:   27 RDLPGP----PQWP--VVGNALQVQLSKVHQNVEAWVKRYGPMIHVRLGGFPLLVVSDHEVIASLLRDRPEGFRRP---SRMQEIMAEMGIQDGVFVAEGEHWAKQRRMVMASFAPGQVRAYLPALLKVAGRLRDRFELAAQQGQAIDLQADLMRFTVDAISGLAFGMDVNTIESDD-------DVIQRHLDQIFPTIWRRSHAIVRYWKWFKL--------PRDRRLDRSVKAVNVAIRGFMAQARVRLQDPARRAAPH---NLLEAMIVAADEPGSGMSDDDVVGNVFTML-------LAGEDTTATSLSWMIYLMSRNPHTLQRARQEVDSCLGDLNNW--TADDLGRLDYLEACIHESMRIKPVGPFNVVQALKD-TVVGDVQIRAGTSVVMVMRHDTLSDDTFPQAQRFMPERWL----DEATQLAPH---------HAKRVSMPFGAGPRICPGRYLALLEIKLVAAMLLQHFDIVSVDTPDGRDADEHMALTMVPVGLKMRIRR 487          

Query:  741 IGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKP--AEILQWKYLPVVTWVRETKQHSRRLEKVIQGAVNAVRADAKLA-DASLGDSAAEGDVGIGGTLLRKIIGATNGTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDL---SLAPGQADPPEEFTSFTCGPKEFDMIL 2204
            + G+ L         Q+E W +++G  ++L +   ++ VV     I  +L  RP  F+R     + +    + G+ + LF   G+TW R RR++    +  +V    P + +V  R  G+    A AG  +  +    RFT D VA   FG DV  + + E       D I+R  + +   + K   A +  W++ P     R   +    +   +QG +   +A ++LA D +L +          G LL  ++ A +  AS  D     + ++     GL +A  +TTA TL W ++ L+++P+   R RAE   V    D ++   EQL RL F  A   E +RLR   P L+F      T      +  G  V+ + R   +SE     A  F PERW    ++   +++ S               +  G GPRICPG+ +A  E  +  A +   F+L       GQA  P E    + GP    M L
Sbjct:   26 VFGNLLQIDSTRVHQQVEAWCEDYGPLFKLRLGKRRIVVVGDHELIAAVLRDRPEGFRR---TQKLEDIGREAGLGAGLFAVNGETWKRQRRMVMAGFDPVHVRRYYPALLRVAGRLVGRWQAAARAGRSIELQADLMRFTVDAVAGLAFGEDVNTLQSDE-------DVIQRHLNRIFPTLFKRIFAPLPTWRWWPSAE-DRALTRSVAEINVAVQGFI--AKARSRLAADPALREKP--------GNLLEAMLVAADTPASGID-----DEQVAGNVLGLLLAGEDTTANTLAWMIWLLSRHPQMLARARAEVDGVL--GDAVLPDLEQLGRLDFVEACAHETMRLRPVGP-LNFAQAVHDTRVGDVAVPAGMVVMAVMRRDAVSERHLHDAAAFDPERWAHDAKQAGAAKRLS---------------MPFGAGPRICPGRYLALMEIKLACAVLLRNFELVAVDTPDGQA--PREHLQLSMGPVGLSMRL 473          

Query:  741 IGGHTLVFRRGESMSQLEGWAKEFGGDYELYVAGNKVTVVTGLSDIRRILTLRPSRFKRGIVVNQTKWAAEQVGVQSSLFFEEGKTWGRSRRLISPNLNGHNVAAMLPIIAKVGERFCGKLGDKADAGEVVTSRDSFARFTHDIVALAVFGVDVGAITATEQEPCPSFDAIERITSALIGLIGKPAEILQWKYLPVVTWVRETKQHSRRLEKVIQGAVNAVRADAKLADASLGDSAAEGDVGIGGTLLRKIIGATNGTASSSDRMLFNERELMHQANGLFVAATETTALTLCWCMYYLTKNPKAALRCRAEALKVAPESDGMVSTAEQLKRLRFCAAVFKEALRLRTPAPRLSFTCMEDFTMKSGRVLKKGTAVLTLNRAAGISEDFFTRADEFVPERWIRSERENALSEKPSTWIGKGGIAHEEEAFLSMGHGPRICPGQDMAKAEGAIIIAAICARFDLSLAP---GQADPPEEFTSFTCGPKEFDMIL 2204
            + G+ L         Q+E W + FG  ++L +   +V VV     I  +L  RP  F+R     + +    ++G+   LF   G+ W R RR++    +  +V    P + +V ER  G+    A     +  +    RFT D VA   FG DV  + + E       D I++  + +  ++ K        + P+ TW    +   R L   +     AV+     A A L  SA  G     G LL  ++ A +   S  D     + ++      + +A  +TTA TL W ++ L+++P+A  + RAE  +V    D  +    QL +L F  A   E +RLR  AP  +   + D T      +  GT V+ + R   +SE     A  F P+RW+   ++  ++++ S               +  G GPRICPG+ +A  E  + +AA+   FD++      GQA  P E      GP    M L
Sbjct:   26 VFGNLLQIDSTRVHQQVEAWCEAFGPVFKLRLGKRRVVVVGDHELITAVLRDRPDGFRR---TQRLEEVGREMGLVGGLFSVNGEVWKRQRRMVMAGFDPVHVKRYYPALLRVAERLVGRWQRAARQDRRIELQADLMRFTVDAVAGLAFGEDVNTLQSDE-------DVIQQHLNRIFPMLFKRM------FSPLPTWRWWPRGEDRALAHSVAAIDVAVQGFIAQARARL--SADPGLRSAPGNLLEAMLVAADEPGSGID-----DAQVAGNVLTMLLAGEDTTANTLAWMIWLLSRHPEALAQARAEVDRVL--GDAALPDLAQLGQLDFVEACAHETMRLRPVAPINTMQAVHD-TRVGDVAVPAGTLVMGVMRHDAVSERHLPGAAAFDPQRWLGDAKQAGVAKRLS---------------MPFGAGPRICPGRYLALMEIKLAMAALLRHFDIAAVDTPDGQA--PREHLQLAMGPVGLSMRL 473