prot_C-tenellus_contig9086.2.1 (polypeptide) Choristocarpus tenellus KU2346

You are viewing a polypeptide, more information available on the corresponding mRNA page

Overview
NamemRNA_C-tenellus_contig9086.2.1
Unique Nameprot_C-tenellus_contig9086.2.1
Typepolypeptide
OrganismChoristocarpus tenellus KU2346 (Choristocarpus tenellus KU2346)
Sequence length249
Homology
BLAST of mRNA_C-tenellus_contig9086.2.1 vs. uniprot
Match: A0A6H5KG47_9PHAE (Uncharacterized protein n=2 Tax=Ectocarpus TaxID=2879 RepID=A0A6H5KG47_9PHAE)

HSP 1 Score: 297 bits (761), Expect = 5.870e-94
Identity = 149/227 (65.64%), Postives = 174/227 (76.65%), Query Frame = 0
Query:    1 MDKLSKSDPFVVVKIKTDVDPEWLELGRTEIVSNTQDPFFTTQLSAMFLFEEVQHLRFEVYDADCVYKSNASSAVLILAKQDFQGSAETTVASVLGSVDQTLGLKLDRPRGKGSTAEVFVRMEEVAHQHDLVTLKLRAAKVDKKDLTSSDPFLRISRALERGEWVSIFKTEVKNRTLNPVWRPIQGSVQRLVNGDLYRPLRFDCWDYDLGGGHDFIGSCEASIIDLQ 227
            MDKLSKSDPFVV+K KTD D  W E+GRTEI+SN Q+P FT Q S  +LFEEVQ +R EVYD D  +K+N ++ V  L +QDFQG AETT+A VLGS  QT  L L +  G+   A V +RM+EV HQHDLVTLKLRA  VDKKDLTSSDP+L+I+R LE GE   IFKTEV++RTLNPVWR IQG+VQ+L NGDL RPLR +CWDYD  GGHDFIG C ASI D+Q
Sbjct:   57 MDKLSKSDPFVVIKWKTDSDETWREIGRTEIISNDQNPNFTAQFSLTYLFEEVQGVRLEVYDVDTAFKTNDATNV-DLGRQDFQGFAETTMAEVLGSSGQTSTLPLMKNTGRAGQAVVSIRMDEVEHQHDLVTLKLRALNVDKKDLTSSDPYLKIARVLETGEQTYIFKTEVQSRTLNPVWREIQGTVQQLANGDLLRPLRVECWDYDRAGGHDFIGGCSASIADMQ 282          
BLAST of mRNA_C-tenellus_contig9086.2.1 vs. uniprot
Match: D7FXN1_ECTSI (Copine n=1 Tax=Ectocarpus siliculosus TaxID=2880 RepID=D7FXN1_ECTSI)

HSP 1 Score: 181 bits (458), Expect = 1.210e-49
Identity = 108/230 (46.96%), Postives = 140/230 (60.87%), Query Frame = 0
Query:    1 MDKLSKSDPFVVVKIKTDVDP-EWLELGRTEIVSNTQDPFFTTQLSAMFLFEEVQHLRFEVYDADCVYKSNASSAVLI-LAKQDFQGSAETTVASVLGSVDQTL-GLKLDRPRGKGSTAEVFVRMEEVAHQHDLVTLKLRAAKVDKKDLTSSDPFLRISRALERGEWVSIFKTEVKNRTLNPVWRPIQGSVQRLVNGDLYRPLRFDCWDYDLGGGHDFIGSCEASIIDLQ 227
            MD  SKSDPFV+VK+ +  D  E  E+GRTEI+SN+ DP F T +   F FEEVQ LRFEVYD D  Y S  S A LI  +KQDFQG+AE  +A V+G  DQT  GL      GKG + +V VR EEVA+ + L  + L  + + K       PFLR+SR  E+G  +  FKTEV   +    W PI+ S++ L NGD YRPL  + + +   G H  +GSC+AS+ DL+
Sbjct:   26 MDTFSKSDPFVLVKLHSPSDSNESKEIGRTEIISNSLDPNFVTIVPVTFKFEEVQTLRFEVYDVDTAYSS--SDATLIDPSKQDFQGAAECVLAQVIGGRDQTWEGLLSGAKTGKGGSPKVVVRAEEVANSNGLAEITLAGSNIGK------GPFLRVSRVSEKGPPIRCFKTEVAKGSPPRPWAPIEISLKVLANGDPYRPLIIEAFTWKKSGNHALLGSCKASVNDLK 247          
BLAST of mRNA_C-tenellus_contig9086.2.1 vs. uniprot
Match: A0A6H5L3T5_9PHAE (C2 domain-containing protein n=1 Tax=Ectocarpus sp. CCAP 1310/34 TaxID=867726 RepID=A0A6H5L3T5_9PHAE)

HSP 1 Score: 174 bits (442), Expect = 6.110e-47
Identity = 106/232 (45.69%), Postives = 140/232 (60.34%), Query Frame = 0
Query:    1 MDKLSKSDPFVVVKIKTDVDP-EWLELGRTEIVSNTQDPFFTTQLSAMFLFEEVQHLRFEVYDADCVYKSNASSAVLILAKQDFQGSAETTVASVLGSVDQTL-GLKLDRPRGKGSTAEVFVRMEEVAHQHDLVTLKLRAAKVDKKDLTSSDPFLRISRALERGEWVSIFKTEVKNRTLNPVWRPIQGSVQRLVNGDLYRPLRFDCWDYD---LGGGHDFIGSCEASIIDLQ 227
            MD  S SDPFV+VKI +  D  E  E+GRTEI+SN+ DP F T +   F FEEVQ LRFEVYD D  Y S+ ++ +   +KQDFQG+AE  +A V+G  DQT  GL     RGKG + +V VR EEVA+   L  + L  + + K       PFLR+SR  E+G  +  FKTEV   +    W PI+ S+Q L NGD YRPL  + + +    L G H  +GSC+AS+ D++
Sbjct:   60 MDAFSNSDPFVLVKIHSPSDSNESKEIGRTEIISNSLDPKFVTIVPVTFKFEEVQTLRFEVYDVDTAYSSSDATHI-DPSKQDFQGAAECALAQVVGGRDQTWEGLLSGAKRGKGGSPKVVVRAEEVANCDGLAQITLAGSNIGKW------PFLRVSRVSEKGPPIRCFKTEVAKGSPPRPWAPIKISLQVLANGDPYRPLLIEAFTWKKRVLSGNHVLLGSCKASVNDIK 284          
BLAST of mRNA_C-tenellus_contig9086.2.1 vs. uniprot
Match: A0A6H5LMQ8_9PHAE (C2 domain-containing protein n=2 Tax=Ectocarpus TaxID=2879 RepID=A0A6H5LMQ8_9PHAE)

HSP 1 Score: 172 bits (436), Expect = 3.980e-46
Identity = 104/232 (44.83%), Postives = 142/232 (61.21%), Query Frame = 0
Query:    1 MDKLSKSDPFVVVKIKTDVDP-EWLELGRTEIVSNTQDPFFTTQLSAMFLFEEVQHLRFEVYDADCVYKSNASSAVLILAKQDFQGSAETTVASVLGSVDQTL-GLKLDRPRGKGSTAEVFVRMEEVAHQHDLVTLKLRAAKVDKKDLTSSDPFLRISRALERGEWVSIFKTEVKNRTLNPVWRPIQGSVQRLVNGDLYRPLRFDCWDYD---LGGGHDFIGSCEASIIDLQ 227
            +D+LSKSDPFV+VK+ +  D  E  E+GRTEI++N+ DP F T +   F FEEVQ LRFEVYD D  Y S+ ++ +   +KQDFQG+AE  +A V+G  DQT  GL     RGKG + +V VR EEVA+ + L  + L  + +          FLRISR  E+G  +  FKTEV   +    W PI+ S+Q L NGD YRPL  + + +    L G H  +GSC+AS+ D++
Sbjct:   56 LDQLSKSDPFVLVKLHSPSDGNESKEIGRTEIITNSLDPKFVTIVPVTFKFEEVQTLRFEVYDVDTAYSSSDATHI-DPSKQDFQGAAECALAQVVGGRDQTWEGLLSGARRGKGDSPKVVVRAEEVANSNALAEITLAGSNI------GHGSFLRISRLSEQGPPIPCFKTEVAKGSPPRPWAPIKISLQVLANGDPYRPLLIEAFTWKKRVLSGNHVLLGSCKASVNDIK 280          
BLAST of mRNA_C-tenellus_contig9086.2.1 vs. uniprot
Match: F2U8H3_SALR5 (Uncharacterized protein n=1 Tax=Salpingoeca rosetta (strain ATCC 50818 / BSB-021) TaxID=946362 RepID=F2U8H3_SALR5)

HSP 1 Score: 162 bits (410), Expect = 6.470e-43
Identity = 94/227 (41.41%), Postives = 127/227 (55.95%), Query Frame = 0
Query:    2 DKLSKSDPFVVVKIKTDVDPEWLELGRTEIVSNTQDPFFTTQLSAMFLFEEVQHLRFEVYDADCVYKSNASSAVLILAKQDFQGSAETTVASVLGSVDQTLGLKLDRPRGKGSTAEVFVRMEEVAHQHDLVTLKLRAAKVDKKDLTS-SDPFLRISRALERGEWVSIFKTEVKNRTLNPVWRPIQGSVQRLVNGDLYRPLRFDCWDYDLGGGHDFIGSCEASIIDLQ 227
            D LSKSDPFVV+    + +  ++E GRTE +SN  +P F T     + FE  Q LRF+VYD D    S        L  QDF G  +TT+ S++G     L   L    GK +   + V  EE A    +V  ++RA KVDKKDL   SDP++ ISR L  G W ++ KTEV   TLNP+W P +  + RL NG+    L+F+ +D+D  G HDFIGS E ++  +Q
Sbjct:   23 DTLSKSDPFVVIYTFDERNNAFVEYGRTETLSNNHNPDFATGFDLSYFFETTQKLRFDVYDEDTKGGS--------LQAQDFIGRIDTTLGSIMGEYHGRLTAPLLSKSGKKTKGVITVLAEEAAKSAGVVKFRMRATKVDKKDLFGKSDPYVVISRNLS-GSWATVHKTEVVRNTLNPLWAPFEVDLTRLCNGNPETALKFEVFDWDRVGSHDFIGSFETTLAAIQ 240          
BLAST of mRNA_C-tenellus_contig9086.2.1 vs. uniprot
Match: A0A6S7I5X7_PARCT (Copine-3-like isoform X1 n=3 Tax=Paramuricea clavata TaxID=317549 RepID=A0A6S7I5X7_PARCT)

HSP 1 Score: 156 bits (395), Expect = 1.080e-42
Identity = 90/227 (39.65%), Postives = 127/227 (55.95%), Query Frame = 0
Query:    2 DKLSKSDPFVVVKIKTDVDPEWLELGRTEIVSNTQDPFFTTQLSAMFLFEEVQHLRFEVYDADCVYKSNASSAVLILAKQDFQGSAETTVASVLGSVDQTLGLKLDRPRGKGSTAEVFVRMEEVAHQHDLVTLKLRAAKVDKKDLTS-SDPFLRISRALERGEWVSIFKTEVKNRTLNPVWRPIQGSVQRLVNGDLYRPLRFDCWDYDLGGGHDFIGSCEASIIDLQ 227
            D LSKSDP  VV I +    +W+E+GRTE + +  +P F   ++  + FEE+Q L+F VYD D             L K DF G  E T+  ++ S   +  L+L    G G+   + +  EE+A  HDLV    RA+K+DKKD    SDP+L  SRA E G +V   +TEV   TLNP W+P + SV  L N DL R ++ DC+D+D  G HDFIG    ++ +++
Sbjct:   37 DVLSKSDPMAVVCIFS--GNQWVEVGRTEQIKDNLNPNFAQSVTVDYHFEELQKLKFSVYDID--------DPKADLRKADFLGELECTLGQLVSSQKYSKPLQLP---GTGNAGTISITAEELATNHDLVDFTFRASKLDKKDFFGKSDPYLEFSRAKEDGSFVVFHRTEVIKNTLNPSWKPFRLSVVDLCNADLNRTIKVDCYDWDSDGSHDFIGQFTTNLNEME 250          
BLAST of mRNA_C-tenellus_contig9086.2.1 vs. uniprot
Match: UPI00106B72FF (copine-8-like n=1 Tax=Dendronephthya gigantea TaxID=151771 RepID=UPI00106B72FF)

HSP 1 Score: 159 bits (403), Expect = 6.670e-42
Identity = 90/228 (39.47%), Postives = 126/228 (55.26%), Query Frame = 0
Query:    1 MDKLSKSDPFVVVKIKTDVDPEWLELGRTEIVSNTQDPFFTTQLSAMFLFEEVQHLRFEVYDADCVYKSNASSAVLILAKQDFQGSAETTVASVLGSVDQTLGLKLDRPRGKGSTAEVFVRMEEVAHQHDLVTLKLRAAKVDKKDLTS-SDPFLRISRALERGEWVSIFKTEVKNRTLNPVWRPIQGSVQRLVNGDLYRPLRFDCWDYDLGGGHDFIGSCEASIIDLQ 227
            MD  SKSDP VV+ IK     EW E GRTE + NT +P F  +    + FEE+QHLRF+VYD D    S+AS     L+  DF G  +TT+ S++G        KL+  +       + + +EEV+   D+VTL  +A K+DKKD    SDPFL   R  E   + ++ +TEV   TLNP W+      + L NGD  R +  +C+D+D  GGHDFIG    ++ ++ 
Sbjct:   46 MDVFSKSDPIVVLFIKATDGSEWREFGRTEKIMNTLNPIFVKKFVMDYFFEEIQHLRFQVYDVD---SSSAS-----LSDHDFIGRLDTTLGSIIGEHGGHFESKLEN-KEMPKCGSIILTVEEVSDCRDVVTLHFKANKLDKKDFFGKSDPFLVFYRCNEDSSFTAVHRTEVIKNTLNPTWKAFSVLSRALCNGDYDRSILVECYDWDRNGGHDFIGQFSTTLREMN 264          
BLAST of mRNA_C-tenellus_contig9086.2.1 vs. uniprot
Match: A0A3M6V0C5_POCDA (Uncharacterized protein n=2 Tax=Pocillopora damicornis TaxID=46731 RepID=A0A3M6V0C5_POCDA)

HSP 1 Score: 158 bits (400), Expect = 1.360e-41
Identity = 92/228 (40.35%), Postives = 127/228 (55.70%), Query Frame = 0
Query:    1 MDKLSKSDPFVVVKIKTDVDPEWLELGRTEIVSNTQDPFFTTQLSAMFLFEEVQHLRFEVYDADCVYKSNASSAVLILAKQDFQGSAETTVASVLGSVDQTLGLKLDRPRGKGSTAEVFVRMEEVAHQHDLVTLKLRAAKVDKKDLTS-SDPFLRISRALERGEWVSIFKTEVKNRTLNPVWRPIQGSVQRLVNGDLYRPLRFDCWDYDLGGGHDFIGSCEASIIDLQ 227
            MD  SKSDP VV+  +     EW E GRTE + NT +P F    +  + FEE+Q LRFEVYD D   K++A      L+  DF G+AE T+ S++G     L  +L  P+ K     + V  EE++   D+VTL+ +  K+DKKD    SDPFL   R  E   + ++ +TEV   TLNP W+P     + L NGD  R +R +C+D+D  GGHD IG    +I +L 
Sbjct:   42 MDVFSKSDPMVVMYTQGMGSKEWREFGRTEHIMNTLNPDFVKTFTIHYFFEEMQKLRFEVYDLD---KNSAK-----LSDHDFIGAAECTLGSIVGEFGGRLQKQLVNPKLK-KPGTIIVSAEELSDCKDVVTLQFKGHKLDKKDFFGKSDPFLVFYRCNEDNSYTAVHRTEVIKNTLNPTWKPFTIHARALCNGDYDRSIRVECYDWDRDGGHDLIGIFSTTINELN 260          
BLAST of mRNA_C-tenellus_contig9086.2.1 vs. uniprot
Match: A0A7S4NWM4_9EUKA (Hypothetical protein (Fragment) n=1 Tax=Paramoeba aestuarina TaxID=180227 RepID=A0A7S4NWM4_9EUKA)

HSP 1 Score: 160 bits (405), Expect = 1.660e-41
Identity = 89/228 (39.04%), Postives = 131/228 (57.46%), Query Frame = 0
Query:    1 MDKLSKSDPFVVVKIKTDVDPEWLELGRTEIVSNTQDPFFTTQLSAMFLFEEVQHLRFEVYDADCVYKSNASSAVLILAKQDFQGSAETTVASVLGSVDQTLGLKLDRPRGKGSTAEVFVRMEEVAHQHDLVTLKLRAAKVDKKDLTS-SDPFLRISRALERGEWVSIFKTEVKNRTLNPVWRPIQGSVQRLVNGDLYRPLRFDCWDYDLGGGHDFIGSCEASIIDLQ 227
            +D  SKSDP V V +K+     W  +G+TE+V +  +P F T ++  F FE VQH++F VYD D  +   A+      A+QD  G A TT+  ++ +  QT+   L  PR + +   + V  EEV        L+     +DKKD    SDPF RISRA E G W +++K++   +TLNPVW P +  VQ+L NGD+ RPL+FD +D++  G  DFIGS   S+ +++
Sbjct:   42 LDTFSKSDPQVWVYMKSQTSDSWGIVGKTEMVKDNLNPNFVTSVTVDFYFEHVQHIKFVVYDID--HPKGAA------AEQDLIGEAFTTIGDIVSAKGQTITKPLQAPRRRRN-GHITVSAEEVKQMKLAAKLRFSGKNLDKKDFFGKSDPFFRISRAKEGGSWDAVYKSDYIRKTLNPVWLPFELPVQKLNNGDMDRPLKFDVYDWNSNGKEDFIGSFTMSLKEME 260          
BLAST of mRNA_C-tenellus_contig9086.2.1 vs. uniprot
Match: UPI001F03D920 (copine-9-like n=1 Tax=Xenia sp. Carnegie-2017 TaxID=2897299 RepID=UPI001F03D920)

HSP 1 Score: 158 bits (400), Expect = 1.680e-41
Identity = 88/228 (38.60%), Postives = 127/228 (55.70%), Query Frame = 0
Query:    1 MDKLSKSDPFVVVKIKTDVDPEWLELGRTEIVSNTQDPFFTTQLSAMFLFEEVQHLRFEVYDADCVYKSNASSAVLILAKQDFQGSAETTVASVLGSVDQTLGLKLDRPRGKGSTAEVFVRMEEVAHQHDLVTLKLRAAKVDKKD-LTSSDPFLRISRALERGEWVSIFKTEVKNRTLNPVWRPIQGSVQRLVNGDLYRPLRFDCWDYDLGGGHDFIGSCEASIIDLQ 227
            MD  SKSDP VV+ +K+    EW E GRTE++ NT +P F  +    + FEE+Q LRF VYD D    SN+      L+  DF G  + T+ S++G     L  KL+  +       + + +EEV+   D+ TL  +A K+DKKD L  SDPFL   R  E   + ++ +TEV   TLNP+W+P     + L NGD  R +  +C+D+D  GGHDFIG    ++ ++ 
Sbjct:   46 MDLFSKSDPVVVLFVKSVDGREWREFGRTEVIMNTLNPVFVKKFIMNYFFEEIQELRFHVYDVD----SNSPR----LSDHDFIGRLDITLGSIIGEHGGRLEAKLEN-KETSKCGSIILTVEEVSECKDVATLHFKANKLDKKDFLGKSDPFLVFYRCNEDSSFTAVHRTEVIKNTLNPMWKPFSVPGRALCNGDYDRSILVECYDWDRDGGHDFIGHFSTTLREMN 264          
The following BLAST results are available for this feature:
BLAST of mRNA_C-tenellus_contig9086.2.1 vs. uniprot
Analysis Date: 2022-09-16 (Diamond blastp: OGS1.0 vs UniRef90)
Total hits: 25
Match NameE-valueIdentityDescription
A0A6H5KG47_9PHAE5.870e-9465.64Uncharacterized protein n=2 Tax=Ectocarpus TaxID=2... [more]
D7FXN1_ECTSI1.210e-4946.96Copine n=1 Tax=Ectocarpus siliculosus TaxID=2880 R... [more]
A0A6H5L3T5_9PHAE6.110e-4745.69C2 domain-containing protein n=1 Tax=Ectocarpus sp... [more]
A0A6H5LMQ8_9PHAE3.980e-4644.83C2 domain-containing protein n=2 Tax=Ectocarpus Ta... [more]
F2U8H3_SALR56.470e-4341.41Uncharacterized protein n=1 Tax=Salpingoeca rosett... [more]
A0A6S7I5X7_PARCT1.080e-4239.65Copine-3-like isoform X1 n=3 Tax=Paramuricea clava... [more]
UPI00106B72FF6.670e-4239.47copine-8-like n=1 Tax=Dendronephthya gigantea TaxI... [more]
A0A3M6V0C5_POCDA1.360e-4140.35Uncharacterized protein n=2 Tax=Pocillopora damico... [more]
A0A7S4NWM4_9EUKA1.660e-4139.04Hypothetical protein (Fragment) n=1 Tax=Paramoeba ... [more]
UPI001F03D9201.680e-4138.60copine-9-like n=1 Tax=Xenia sp. Carnegie-2017 TaxI... [more]

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InterPro
Analysis Name: InterProScan on OGS1.0
Date Performed: 2022-09-29
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000008C2 domainSMARTSM00239C2_3ccoord: 131..235
e-value: 1.4E-6
score: 37.9
coord: 2..103
e-value: 15.0
score: 6.3
IPR000008C2 domainPFAMPF00168C2coord: 1..86
e-value: 9.2E-7
score: 29.1
coord: 136..223
e-value: 8.5E-9
score: 35.6
IPR000008C2 domainPROSITEPS50004C2coord: 1..88
score: 9.879
IPR000008C2 domainPROSITEPS50004C2coord: 136..220
score: 10.323
IPR035892C2 domain superfamilyGENE3D2.60.40.150C2 domaincoord: 1..123
e-value: 2.9E-11
score: 45.4
IPR035892C2 domain superfamilyGENE3D2.60.40.150C2 domaincoord: 126..230
e-value: 1.6E-13
score: 52.9
IPR035892C2 domain superfamilySUPERFAMILY49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 1..116
IPR035892C2 domain superfamilySUPERFAMILY49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 109..226
NoneNo IPR availablePANTHERPTHR10857COPINEcoord: 2..227
NoneNo IPR availableCDDcd04048C2A_Copinecoord: 1..114
e-value: 8.06305E-35
score: 119.211
IPR037768Copine, C2B domainCDDcd04047C2B_Copinecoord: 130..223
e-value: 1.16274E-37
score: 126.141

Alignments
The following features are aligned
Aligned FeatureFeature TypeAlignment Location
C-tenellus_contig9086contigC-tenellus_contig9086:1552..4447 -
Analyses
This polypeptide is derived from or has results from the following analyses
Analysis NameDate Performed
InterProScan on OGS1.02022-09-29
Diamond blastp: OGS1.0 vs UniRef902022-09-16
Choristocarpus tenellus KU2346 OGS1.02022-07-08
Relationships

This polypeptide derives from the following mRNA feature(s):

Feature NameUnique NameSpeciesTypePosition
mRNA_C-tenellus_contig9086.2.1mRNA_C-tenellus_contig9086.2.1Choristocarpus tenellus KU2346mRNAC-tenellus_contig9086 611..5142 -


Sequences
The following sequences are available for this feature:

polypeptide sequence

>prot_C-tenellus_contig9086.2.1 ID=prot_C-tenellus_contig9086.2.1|Name=mRNA_C-tenellus_contig9086.2.1|organism=Choristocarpus tenellus KU2346|type=polypeptide|length=249bp
MDKLSKSDPFVVVKIKTDVDPEWLELGRTEIVSNTQDPFFTTQLSAMFLF
EEVQHLRFEVYDADCVYKSNASSAVLILAKQDFQGSAETTVASVLGSVDQ
TLGLKLDRPRGKGSTAEVFVRMEEVAHQHDLVTLKLRAAKVDKKDLTSSD
PFLRISRALERGEWVSIFKTEVKNRTLNPVWRPIQGSVQRLVNGDLYRPL
RFDCWDYDLGGGHDFIGSCEASIIDLQVLLLLMILFVGEWGGIFGNCS*
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Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000008C2_dom
IPR035892C2_domain_sf
IPR037768C2B_Copine